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Anti-topoisomerase I antibodies in systemic lupus erythematosus as a marker of severe nephritis

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Abstract

The authors report nine patients with systemic lupus erythematosus associated with anti-topoisomerase I antibodies (ELISA test) without features of systemic sclerosis. These antibodies were correlated with the disease activity and might be a marker of the severity of the closely related to difusse proliferative glomerulonephritis.

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Authors and Affiliations

  1. Department of Internal Medicine, University Hospital Hôtel-Dieu, Place Alexis Ricordeau, 44 035, Nantes, France

    Mohamed A. Hamidou, Agathe Masseau & Christian Agard

  2. Laboratory of Immunology, University Hospital Hôtel-Dieu, Nantes, France

    Marie A. Audrain

  3. Laboratory of Pathology, University Hospital Hôtel-Dieu, Nantes, France

    Anne Moreau

Authors
  1. Mohamed A. Hamidou
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  2. Marie A. Audrain
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  3. Agathe Masseau
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  4. Christian Agard
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  5. Anne Moreau
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Corresponding author

Correspondence to Mohamed A. Hamidou.

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Hamidou, M.A., Audrain, M.A., Masseau, A. et al. Anti-topoisomerase I antibodies in systemic lupus erythematosus as a marker of severe nephritis. Clin Rheumatol 25, 542–543 (2006). https://doi.org/10.1007/s10067-005-0061-9

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  • DOI: https://doi.org/10.1007/s10067-005-0061-9

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