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The relationship between severity and extent of spinal involvement and spinal mobility and physical functioning in patients with ankylosing spondylitis

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Abstract

The present study was undertaken to determine the relationship between spinal radiological changes of ankylosing spondylitis (AS), spinal mobility, and physical functioning. Thirty-one patients diagnosed as AS according to the modified New York criteria for AS were included in this study. Three radiographic scoring methods were used to assess spinal damage. Severity of spinal involvement was assessed by using Stoke Ankylosing Spondylitis Spine Score (SASSS) and Bath Ankylosing Spondylitis Radiographic Index–Spine (BASRI–S). To assess the extent of spinal involvement, the total number of vertebrae showing radiological findings attributable to AS [number of vertebrae involved (NoVI)] was calculated according to the AS grading system defined by Braun et al. Statistical analysis, consisting of bivariate correlation, Spearman correlation, and multiple linear regression analysis, was performed using Windows Statistical Package for the Social Sciences 13.0. NoVI was negatively correlated with modified Schober and lateral spinal flexion and was positively correlated with occiput-to-wall distance and BASMI. SASSS was negatively correlated with the modified Schober. BASRI–S was negatively correlated with the modified Schober and positively correlated with BASMI. When BASMI and Bath Ankylosing Spondylitis Functional Index were taken as dependent variables, only the NoVI was found to be associated with BASMI. In our data, the extent of spinal involvement (NoVI) showed a more significant correlation with spinal measurements such as modified Schober and BASMI as compared with the other radiologic scores (SASSS and BASRI–S). Furthermore, because only the NoVI was found to be associated with BASMI, we can conclude that the extent of spinal involvement, which also includes thoracic vertebrae, affects spinal measurements.

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References

  1. Brophy S, Mackay K, Al-Saidi A, Taylor G, Calin A (2002) The natural history of ankylosing spondylitis as defined by radiological progression. J Rheumatol 29(6):1236–1243

    PubMed  Google Scholar 

  2. Van der Heijde D, Spoorenberg A (1999) Plain radiographs as an outcome measure in ankylosing spondylitis. J Rheumatol 26(4):985–987

    PubMed  Google Scholar 

  3. Braun J, Golder W, Bollow M, Sieper J, van der Heijde D (2002) Imaging and scoring in ankylosing spondylitis. Clin Exp Rheumatol 20[Suppl 28]:178–184

    Google Scholar 

  4. de Vlam K, Mielants H, Veys ME (1999) Involvement of the zygapophyseal joint in ankylosing spondylitis: relation to the bridging syndesmophyte. J Rheumatol 26:1738–1745

    PubMed  Google Scholar 

  5. Dawes PT (1999) Stoke ankylosing spondylitis spine score. J Rheumatol 26(4):993–996

    PubMed  CAS  Google Scholar 

  6. Mackay K, Mack C, Brophy S, Calin A (1998) The Bath Ankylosing Spondylitis Radiology Index (BASRI). Arthritis Rheum 41(12):2263–2270

    Article  PubMed  CAS  Google Scholar 

  7. Averns HL, Oxtoby J, Taylor HG, Jones PW, Dziedzic K, Dawes P (1996) Radiological outcome in ankylosing spondylitis: use of the Stoke Ankylosing Spondylitis Spine Score (SASSS). Br J Rheumatol 35:373–376

    PubMed  CAS  Google Scholar 

  8. Braun J, van der Heijde D, Dougados M, Emery P, Khan MA, Sieper J, van der Linden S (2002) Staging of patients with ankylosing spondylitis: a preliminary proposal. Ann Rheum Dis 61[Suppl III]:iii19–iii23

    Google Scholar 

  9. Davis JC Jr (2005) Ankylosing spondylitis. In: Koopman WJ, Moreland LW (eds) Arthritis and allied conditions. A textbook of rheumatology. Lippincott Williams and Wilkins, Philadelphia, pp 1319–1334

    Google Scholar 

  10. Calin A, Garret S, Whitelock H, Kennedy LG, O’hea J, Mallorie P, Jenkinson T (1994) A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index. J Rheumatol 21:2281–2285

    PubMed  CAS  Google Scholar 

  11. Garret S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A (1994) A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 21:2286–2291

    PubMed  Google Scholar 

  12. Karatepe AG, Akkoc Y, Akar S, Kirazlı Y, Akkoc N (2005) The Turkish versions of the Bath Ankylosing Spondylitis and Dougados Functional Indices: reliability and validity. Rheumatol Int 25(8):612–618 (Oct, Epub: Jul 10, 2004)

    Article  PubMed  Google Scholar 

  13. Akkoc Y, Karatepe AG, Akar S, Kirazlı Y, Akkoc N (2005) A Turkish version of the Bath Ankylosing Spondylitis Disease Activity Index: reliability and validity. Rheumatol Int 25(4):280–284 (May, Epub: Jan 17, 2004)

    Article  PubMed  Google Scholar 

  14. Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garret SL, Calin A (1994) Defining spinal mobility in ankylosing spondylitis (AS). The Bath AS Metrology Index. J Rheumatol 21:1694–1698

    PubMed  CAS  Google Scholar 

  15. Jones SD, Steiner A, Garret SL, Calin A (1996) The Bath Ankylosing Spondylitis Patient Global Score (BAS-G). Br J Rheumatol 35(1):66–71

    Article  PubMed  CAS  Google Scholar 

  16. Calin A (1989). Ankylosing spondylitis. In: Kelley WN, Harris ED, Ruddy S, Sledge CB (eds). Textbook of rheumatology. Saunders, Philadelphia, pp 1021–1037

    Google Scholar 

  17. Van der Heijde D, Spoorenberg A (1999) Plain radiographs as an outcome measure in ankylosing spondylitis. J Rheumatol 26:985–987

    PubMed  Google Scholar 

  18. Resnick D, Niwayama G (1989) Ankylosing sponylitis. In: Resnick D (ed) Bone and joint imaging. Saunders, Philadelphia, pp 299–319

    Google Scholar 

  19. Spoorenberg A, de Vlam K, van der Linden S, Dougados M, Mielants H, van de Tempel H, van der Heijde D (2004) Radiologic scoring methods in ankylosing spondylitis. Reliability and change over 1 and 2 years. J Rheumatol 31(1):125–132

    PubMed  Google Scholar 

  20. Creemers MCW, Franssen MJAM, van’t Hof MA, Gribnau FWJ, van de Putte LBA, van Riel PLCM (2005) Assessment of outcome in ankylosing spondylitis: an extended radiographic scoring system. Ann Rheum Dis 64:127–129

    Article  PubMed  CAS  Google Scholar 

  21. Wanders A, Landewé R, Dougados M, Mielants H, van der Linden S, van der Heijde D (2005) Association between radiographic damage of the spine and spinal mobility for individual patients with ankylosing spondylitis: can assessment of spinal mobility be a proxy for radiographic evaluation? Ann Rheum Dis 64(7):988–994

    Article  PubMed  CAS  Google Scholar 

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Author notes

  1. Taciser Kaya

    Present address: Camtepe mah. Canlar Sok. No. 13/28, Narlidere, 35320, Izmir, Turkey

Authors and Affiliations

  1. Physical Medicine and Rehabilitation Department, Izmir Training and Research Hospital, Izmir, Turkey

    Taciser Kaya & Rezzan Gunaydin

  2. Radiology Department, Ataturk Training and Research Hospital, Izmir, Turkey

    Fazil Gelal

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  1. Taciser Kaya
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  2. Fazil Gelal
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  3. Rezzan Gunaydin
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Correspondence to Taciser Kaya.

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Kaya, T., Gelal, F. & Gunaydin, R. The relationship between severity and extent of spinal involvement and spinal mobility and physical functioning in patients with ankylosing spondylitis. Clin Rheumatol 25, 835–839 (2006). https://doi.org/10.1007/s10067-005-0180-3

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  • DOI: https://doi.org/10.1007/s10067-005-0180-3

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