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Hypogonadism and neurological diseases

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Abstract

Affected patients with hypogonadism have unnaturally low amounts of sex hormones that produce male and female sex characteristics. Males who suffer from this condition lack testosterone, while females fail to produce enough estrogen. Hypogonadism may be present at birth, or it may take effect years later following injury or illness to the sex glands. Hypogonadism has remarkable associations with variable medical disorders; however, it is characterized by a distinctive association with variable neurological disorders: such as epilepsy, ataxia, dysmyelination, nerve muscle disease, movement disorders, mental retardation and deafness. The remarkable neurological diseases with hypogonadism should not basically be regarded as coincidental findings, but possibly related to an intrinsic pathophysiological association.

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  1. Neurology Section, Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, MBC. 76, P.O. Box 3354, Riyadh, 11211, Kingdom of Saudi Arabia

    Abdulaziz Alsemari

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Alsemari, A. Hypogonadism and neurological diseases. Neurol Sci 34, 629–638 (2013). https://doi.org/10.1007/s10072-012-1278-4

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