Abstract
The intracerebral hemorrhage (ICH) score and the ICH-grading scale (ICH-GS) are mortality predictor tools developed predominantly in conservatively treated ICH cohorts. We aimed to compare and evaluate the external validity of both models in predicting mortality in patients with ICH undergoing surgical intervention. A retrospective review of all patients presenting with spontaneous ICH admitted to a Peruvian national hospital between January 2018 and March 2020 was conducted. We compared the area under the receiver operating characteristic curve (AUC) for the ICH score and ICH-GS for in-hospital, 30-day, and 6-month mortality prediction. The research protocol was approved by the Institutional Review Board. A total of 73 patients (median age 62 years, 56.2% males) were included in the study. The mean ICH and ICH-GS scores were 2.5 and 8.7, respectively. In-hospital, 30-day, and 6-month mortality were 37%, 27.4%, and 37%, respectively. The AUC for in-hospital, 30-day, and 6-month mortality was 0.69, 0.71, and 0.69, respectively, for the ICH score and 0.64, 0.65, and 0.68, respectively, for the ICH-GS score. In this study, the ICH score and ICH-GS had moderate discrimination capacities to predict in-hospital, 30-day, and 6-month mortality in surgically treated patients. Additional studies should assess whether surgical intervention affects the discrimination of these prognostic models in order to develop predictive scores based on specific populations.
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The data that support the findings of this study are available from the corresponding author on reasonable request.
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We thank Dr. John F. Vargas Urbina and Gianfranco Reyes Narro for their contribution in data recollection.
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All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by Aaron Rodriguez Calienes, Marco Malaga, and Giancarlo Saal Zapata. The first draft of the manuscript was written by Aaron Rodriguez Calienes and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Ethical approval was waived by the local Ethics Committee of Hospital Nacional Guillermo Almenara Irigoyen in view of the retrospective nature of the study and all the procedures being performed were part of the routine care.
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Rodriguez-Calienes, A., Malaga, M., Alva-Diaz, C. et al. Validation of the ICH score and ICH-GS in a Peruvian surgical cohort: a retrospective study. Neurosurg Rev 45, 763–770 (2022). https://doi.org/10.1007/s10143-021-01605-2
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DOI: https://doi.org/10.1007/s10143-021-01605-2