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Cotyledonoid dissecting leiomyoma of the uterus with intravascular growth in postmenopausal woman: a case presentation

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Abstract

Cotyledonoid dissecting leiomyoma (“Sternberg tumor”) is an unusual type of a benign uterine smooth-muscle tumor with a distinctive gross appearance. A 57-year-old woman (gravida 7, para 6), in menopause for 3 years, presented with a 3–4-year history of increased pelvic pain. The transvaginal ultrasound scan showed a 2.5 cm sized heterogenic mass in the uterus cavity and 4 × 5 cm sized irregular contoured mass in the right lateral aspect of the uterus. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed with removal of the pelvic tumor extension. Definite pathologic examination result was cotyledonoid dissecting leiomyoma of the uterus with intravascular growth. The patient is receiving follow-up care every 6 months, and she has no evidence of disease after 22 months of follow-up. The worrying appearance of the gross specimen is often mistaken for malignant or non-uterine lesions that may result in overtreatment. It is important to be aware of this entity to prevent overly aggressive treatment for this benign smooth-muscle neoplasm.

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References

  1. Clement PB (1993) Pure mesenchymal tumors. In: Tumor and tumor-like lesions of the uterine corpus and cervix, Churchill Livingstone, New York, pp 265–274

  2. Roth LM, Reed RJ, Sternberg WH (1996) Cotyledonoid dissecting leiomyoma of the uterus. The Sternberg tumor. Am J Surg Pathol 20:1455–1461

    Article  PubMed  CAS  Google Scholar 

  3. David MP, Homonnai TZ, Deligdish L et al (1975) Grape-like leiomyomas of the uterus. Int Surg 60:238–239

    PubMed  CAS  Google Scholar 

  4. Driss M, Zhioua F, Doghri R et al (2009) Cotyledonoid dissecting leiomyoma of the uterus associated with endosalpingiosis. Arch Gynecol Obstet 280(6):1063–1065

    Article  PubMed  Google Scholar 

  5. Menolascino-Brrata F, Garcia de Barriola V, Navajo de Gomez M et al (1999) Cotyledonoid dissecting leiomyoma (Sternberg tumor): an unusual form of leiomyoma. Pathol Res Pract 195:435–438

    Article  Google Scholar 

  6. Saeed AS, Hanaa B, Faisal AS et al (2006) Cotyledonoid dissecting leiomyoma of the uterus: a case report of a benign uterine tumor with sarcoma-like gross appearance and review of literature. Int J Gynecol Pathol 25:262–267

    Article  PubMed  Google Scholar 

  7. Misir A, Daya D, Monalisa S (2009) Cotyledonoid dissecting leiomyoma of the uterus (Sternberg tumour). A clinicopathological study of six cases. Official Publication of the Canadian Association of Pathologists 1(3):9–15

    Google Scholar 

  8. Adedipe TO, Vine SJ (2010) Dissecting cotyledonoid leiomyoma: a rare cause of chronic intractable menorrhagia (not amenable to medical treatment). Case report. Eur J Gynaecol Oncol 31(2):230–232

    Google Scholar 

  9. Fukunaga M, Suzuki K, Hiruta N (2010) Cotyledonoid dissecting leiomyoma of the uterus: a report of four cases. APMIS 118(4):331–333

    Article  PubMed  Google Scholar 

  10. Jordan LB, Al-Nafussi A, Beattie G (2002) Cotyledonoid hydropic intravenous leiomyomatosis: a new variant leiomyoma. Histopathology 40:245–252

    Article  PubMed  CAS  Google Scholar 

  11. Brand AH, Scurry JP, Planner RS et al (1995) Grapelike leiomyoma of the uterus. Am J Obstet Gynecol 173:959–961

    Article  PubMed  CAS  Google Scholar 

  12. Cheuk W, Chan JK, Liu JY (2002) Cotyledonoid leiomyoma: a benign uterine tumor with alarming gross appearance. Arch Pathol Lab Med 126:210–213

    PubMed  CAS  Google Scholar 

  13. Fukunaga M, Ushigome S (1998) Dissecting leiomyoma of the uterus with extrauterine extension. Histopathology 32:160–164

    Article  PubMed  CAS  Google Scholar 

  14. Shelekhova KV, Kazakov DV, Michal M (2007) Cotyledonoid dissecting leiomyoma of the uterus with intravascular growth: report of two cases. Virchows Arch 450:119–121

    Article  PubMed  Google Scholar 

  15. Mathew M, Gowri V, Al Hamdani A et al (2007) Cotyledonoid leiomyoma in pregnancy. Obstet Gynecol 109:509–511

    Article  PubMed  CAS  Google Scholar 

  16. Kim MJ, Park YK, Cho JH (2002) Cotyledonoid dissecting leiomyoma of the uterus: a case report and review of the literature. J Korean Med Sci 17:840–844

    PubMed  Google Scholar 

  17. Weissferdt A, Maheshwari MB, Downey GP et al (2007) Cotyledonoid dissecting leiomyoma of the uterus: a case report. Diagn Pathol 2:18

    Article  PubMed  Google Scholar 

  18. Roth LM, Reed RJ (2000) Cotyledonoid leiomyoma of the uterus: report of a case. Int J Gynecol Pathol 19:272–275

    Article  PubMed  CAS  Google Scholar 

  19. Gurbuz A, Karateke A, Kabaca C et al (2005) A case of cotyledonoid leiomyoma and review of the literature. Int J Gynecol Cancer 15:121–122

    Google Scholar 

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Correspondence to Kazim Gezginç.

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Gezginç, K., Yazici, F., Selimoğlu, R. et al. Cotyledonoid dissecting leiomyoma of the uterus with intravascular growth in postmenopausal woman: a case presentation. Int J Clin Oncol 16, 701–704 (2011). https://doi.org/10.1007/s10147-011-0184-8

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  • DOI: https://doi.org/10.1007/s10147-011-0184-8

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