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La chimiothérapie dans les cancers colorectaux chez les sujets âgés

Chemotherapy for colorectal cancer in elderly patients

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  • Published:
Oncologie

Résumé

Le cancer colorectal survient après 75 ans dans près de la moitiédes cas. Les patients âgés restent globalement soustraités et sont loin de bénéficier d’une prise en charge optimale. Les données disponibles suggèrent que chez les patients âgés en bon état général et sans comorbidités importantes, l’efficacité des chimiothérapies est proche de ce qui est observé chez les patients plus jeunes avec cependant une possible majoration de la toxicité, en particulier hématologique.

Abstract

Colorectal cancer occurs after the age of 75 in 50% of cases, but elderly patients are generally under-treated and receive far from optimal management of their disease. Available data suggests, however, that among elderly patients in general good health and with no severe comorbidities, the efficacy of chemotherapy is similar to that observed in younger patients, though with a trend towards increased hematological toxicity.

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  1. Service d’hépatogastro-entérologie et oncologie digestive, UFR médecine Paris-Île-de-France-Ouest, université Versailles-Saint-Quentin, CHU Ambroise-Paré, APHP, 9, avenue Charles-de-Gaulle, F-92100, Boulogne, France

    E. Mitry

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Mitry, E. La chimiothérapie dans les cancers colorectaux chez les sujets âgés. Oncologie 10, 182–186 (2008). https://doi.org/10.1007/s10269-008-0844-0

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  • DOI: https://doi.org/10.1007/s10269-008-0844-0

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