Résumé
Les tumeurs urothéliales sont classées en fonction de leur grade, degré d’agressivité cytologique et leur stade, niveau d’infiltration de la paroi vésicale. La parution, en avril 2004, du livre de l’OMS a enfin permis la large diffusion de la nouvelle classification du grade des tumeurs vésicales dite « de consensus » entre l’OMS et l’ISUP qui avait été proposée dès 1998. Cette nouvelle classification insiste par ailleurs sur la description de « variantes morphologiques » des tumeurs urothéliales essentiellement infiltrantes qui se caractérisent par une morphologie différente et une évolution le plus souvent mais non constamment plus péjorative. Ces différents caractères que sont le grade et le stade permettent de décider de la prise en charge thérapeutique et de la surveillance ultérieure de ces tumeurs. Les modes d’évaluation de ces critères ont évolué au cours du temps.
Abstract
Urothelial tumors are classified according to their grade, degree of cytological aggression, stage, and level of infiltration of the vesical wall. A new classification system was proposed by WHO/ISUP in 1998 and updated by WHO in April 2004. This new classification also insists on the description of “morphological variants” of essentially infiltrating urothelial tumors that are characterized by different morphology and evolution most often but not consistently more pejorative. The therapeutic treatment and subsequent monitoring of these tumors depend upon the tumor’s stage and grade.
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Mazerolles, C., Delas, A. Différentes classifications des tumeurs urothéliales. Oncologie 17, 143–149 (2015). https://doi.org/10.1007/s10269-015-2501-8
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DOI: https://doi.org/10.1007/s10269-015-2501-8