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A case of mitochondrial disease with severe left ventricular hypertrophy

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Abstract

A 35-year-old woman was admitted for progressive dyspnea with lower limb edema. Transthoracic echocardiography showed severe left ventricular hypertrophy (LVH) and heart failure with preserved ejection fraction (HFPEF). Electron microscopy of an endomyocardial biopsy sample revealed a high density of mitochondria of abnormal size and shape. We report a case of mitochondrial disease with severe LVH and HFPEF.

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Authors and Affiliations

  1. Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan

    Kosuke Uchida, Shigeki Kobayashi, Hiroshi Nakamura, Shinichi Okuda, Chikage Oshita, Takehisa Susa, Wakako Murakami & Masunori Matsuzaki

  2. Division of Laboratory, Yamaguchi University Hospital, Minamikogushi, Ube, Yamaguchi, 755-8505, Japan

    Kazuya Murata

  3. Advanced Medical Emergency and Critical Care Center, Yamaguchi University Hospital, Ube, Japan

    Yasuaki Wada

Authors
  1. Kosuke Uchida
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  2. Kazuya Murata
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  3. Shigeki Kobayashi
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  4. Hiroshi Nakamura
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  5. Yasuaki Wada
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  6. Shinichi Okuda
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  7. Chikage Oshita
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  8. Takehisa Susa
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  9. Wakako Murakami
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  10. Masunori Matsuzaki
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Corresponding author

Correspondence to Kazuya Murata.

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Uchida, K., Murata, K., Kobayashi, S. et al. A case of mitochondrial disease with severe left ventricular hypertrophy. J Med Ultrasonics 38, 157–159 (2011). https://doi.org/10.1007/s10396-011-0306-y

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  • DOI: https://doi.org/10.1007/s10396-011-0306-y

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