We studied the influence of vascular prostheses made of polytetrafluoroethylene and polyethylene terephthalate on the proliferation, migration, and NO production by bone marrow mesenchymal stem cells, human endothelial progenitor cells, and EA.hy926 endothelial cells, colonization of the prosthesis surface by endothelial and mesenchymal cells was also analyzed. Synthetic prostheses have a negative effect on cell proliferation and migration, while surface treatment with proteins (fibronectin or gelatin) promotes colonization of the prostheses with cells.
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Translated from Kletochnye Tekhnologii v Biologii i Meditsine, No. 4, pp. 269-274, December, 2018
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Lykov, A.P., Poveshchenko, O.V., Surovtseva, M.A. et al. Effect of Polyethylene Terephthalate on Functional Properties of Endothelial and Mesenchymal Cells. Bull Exp Biol Med 166, 580–585 (2019). https://doi.org/10.1007/s10517-019-04395-2
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DOI: https://doi.org/10.1007/s10517-019-04395-2