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Synthesis of new betulonic and oleanonic acid amides

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Chemistry of Natural Compounds Aims and scope

Amides of betulonic and oleanonic acids with diethylenetriamine, triethylenetetramine, and spermidine were synthesized. Antitumor activity in vitro was not found for the conjugate of betulonic acid with diethylenetriamine.

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Acknowledgment

The work was supported financially by the RFBR (Project No. 08-03-00868). We thank the National Cancer Institute (NCI) for determining the antitumor activity of 3 in vitro.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Scientific Center, Russian Academy of Sciences, 450054, Ufa, pr. Oktyabrya, 71, Russia

    G. V. Giniyatullina, O. B. Kazakova, E. V. Salimova & G. A. Tolstikov

Authors
  1. G. V. Giniyatullina
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  2. O. B. Kazakova
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  3. E. V. Salimova
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  4. G. A. Tolstikov
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Corresponding author

Correspondence to O. B. Kazakova.

Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 62–65, January–February, 2011.

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Giniyatullina, G.V., Kazakova, O.B., Salimova, E.V. et al. Synthesis of new betulonic and oleanonic acid amides. Chem Nat Compd 47, 68–72 (2011). https://doi.org/10.1007/s10600-011-9832-5

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  • DOI: https://doi.org/10.1007/s10600-011-9832-5

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