A new furanocoumarin oncosepalin A (1), together with two known compounds, ferulic acid and β-sitosterol, was isolated from the roots of Angelica oncosepala. The structure of the new compound was elucidated by spectroscopic methods, including extensive 1D and 2D NMR experiments, as well as high-resolution EI mass analysis. Compound 1 showed cytotoxic inhibition against HL-60 human tumor cell lines with an IC50 value of 2.04 μM.
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Acknowledgment
This work was financially supported by the Natural Science Foundation of Yunnan Province (No. 2008ZC110M) and the International Cooperation Foundation of Yunnan Province of China (No. 30811120009).
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2012, pp. 672–673.
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Zheng, B., Qing, C., Wang, JL. et al. A new furanocoumarin from the roots of Angelica oncosepala . Chem Nat Compd 48, 748–750 (2012). https://doi.org/10.1007/s10600-012-0373-3
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DOI: https://doi.org/10.1007/s10600-012-0373-3