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Immunologic Function of Dendritic Cells in Esophageal Cancer

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Abstract

Esophageal cancer is one of the frequently occurring malignant cancers. The current therapy, including surgery, chemotherapy, radiotherapy, or a combination, is only to palliate the symptoms; overall the prognosis is poor. The immunotherapy of dendritic cells for esophageal cancer is a valuable method. Dendritic cells existing in the esophageal tissues play an important role in the host’s immunosurveillance against cancer as the professional antigen-presenting cells. This review concerns the immunology of dendritic cells in esophageal cancer; it describes the expression of DCs in the normal esophageal tissues and benign disease of esophagus, relations between the DCs and cancer development in esophageal cancer, and the DC-based approach to establish treatment for esophageal cancer.

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Authors and Affiliations

  1. Department of Thoracic Surgery, Shandong Cancer Hospital and Institute, Jiyan Road 440, Jinan, 250117, Shandong Province, P.R. China

    Wenfeng Yang

  2. Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Jiyan Road 440, Jinan, 250117, Shandong Province, P.R. China

    Jinming Yu

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  1. Wenfeng Yang
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  2. Jinming Yu
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Correspondence to Jinming Yu.

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Yang, W., Yu, J. Immunologic Function of Dendritic Cells in Esophageal Cancer. Dig Dis Sci 53, 1739–1746 (2008). https://doi.org/10.1007/s10620-007-0095-8

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  • DOI: https://doi.org/10.1007/s10620-007-0095-8

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