Skip to main content

Advertisement

Log in

Retrospective review on the outcome and safety of transscleral diode laser cyclophotocoagulation in refractory glaucoma in Chinese patients

  • Original Paper
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

Transscleral cyclodiode laser cyclophotocoagulation (TSCP) is often reserved for treatment of refractory glaucoma. This retrospective study investigates the safety and efficacy of TSCP among the Chinese population.

Methods

A retrospective review was performed on electronic patient records of all patients receiving TSCP between years 2009 to year 2016. Patient demographics, indication for laser, success and response rate, change in intraocular pressure (IOP), number of treatment sessions, laser energy, glaucoma medication, visual acuity, pain symptoms and complication rate were documented.

Results

The study included 126 patients: 81 patients were male and 45 were female, and the mean age was 66.6 ± 14.3 years old and the mean follow-up was 22.7 ± 14.1 months. The mean number of treatment sessions was 1.5 ± 0.8. The success rate was 67.3%. The mean IOP before TSCP was 67 ± 38.6 mmHg and 22.8 ± 14.2 mmHg after TSCP, the mean IOP reduction was 38.4%, which was statistically significant (P value < 0.001, Wilcoxon signed rank test). The mean laser energy used per eye was 72.7 ± 56.6 and 49.2 ± 22.9 J per individual treatment session. The mean number of laser shots was 15.0 ± 6.1. 71% of patients were able to reduce their glaucoma medication after TSCP, (P value < 0.01, Wilcoxon signed rank test). 86.1% of patients had improvement in pain symptoms after TSCP. The overall complication rate was 7.1%.

Conclusion

TSCP was found to be safe and effective among the Chinese population, with comparably low laser energy setting and complication rate. It was found to be most effective in treatment of glaucoma due to trauma, acute angle closure, uveitis and chronic angle closure.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Kaushik S, Pandav SS, Jain R, Bansal S, Gupta A (2008) Lower energy levels adequate for effective transscleral diode laser cyclophotocoagulation in Asian eyes with refractory glaucoma. Eye (Lond) 22(3):398–405

    Article  CAS  Google Scholar 

  2. Frezzotti P, Mittica V, Martone G, Motolese I, Lomurno L, Peruzzi S, Motolese E (2010) Longterm follow-up of diode laser transscleral cyclophotocoagulation in the treatment of refractory glaucoma. Acta Ophthalmol 88(1):150–155

    Article  PubMed  Google Scholar 

  3. Ansari E, Gandhewar J (2006) Long-term efficacy and visual acuity following transscleral diode laser photocoagulation in cases of refractory and non-refractory glaucoma. Eye 21(7):936–940

    Article  PubMed  Google Scholar 

  4. Murphy CC, Burnett CA, Spry PG, Broadway DC, Diamond JP (2003) A two centre study of the dose-response relation for transscleral diode laser cyclophotocoagulation in refractory glaucoma. Br J Ophthalmol 87(10):1252–1257

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Pucci V, Tappainer F, Borin S, Bellucci R (2003) Long-term follow-up after transscleral diode laser photocoagulation in refractory glaucoma. Ophthalmologica 217(4):279–283

    Article  PubMed  Google Scholar 

  6. Iliev ME, Gerber S (2007) Long-term outcome of trans-scleral diode laser cyclophotocoagulation in refractory glaucoma. Br J Ophthalmol 91(12):1631–1635

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  7. Kirwan JF, Shah P, Khaw PT (2002) Diode laser cyclophotocoagulation: role in the management of refractory pediatric glaucomas. Ophthalmology 109(2):316–323

    Article  PubMed  Google Scholar 

  8. Rotchford AP, Jayasawal R, Madhusudhan S, Ho S, King AJ, Vernon SA (2010) Transscleral diode laser cycloablation in patients with good vision. Br J Ophthalmol 94(9):1180–1183

    Article  PubMed  CAS  Google Scholar 

  9. Cantor LB, Nichols DA, Katz LJ, Moster MR, Poryzees E, Shields JA, Spaeth GL (1989) Neodymium-YAG transscleral cyclophotocoagulation. The role of pigmentation. Invest Ophthalmol Vis Sci 30(8):1834–1837

    PubMed  CAS  Google Scholar 

  10. Fankhauser F, van der Zypen E, Kwasniewska S, Rol P, England C (1986) Transscleral cyclophotocoagulation using a neodymium YAG laser. Ophthalmic Surg 17(2):94–100

    PubMed  CAS  Google Scholar 

  11. Hawkins TA, Stewart WC (1993) One-year results of semiconductor transscleral cyclophotocoagulation in patients with glaucoma. Arch Ophthalmol 111(4):488–491

    Article  PubMed  CAS  Google Scholar 

  12. Wong EY, Chew PT, Chee CK, Wong JS (1997) Diode laser contact transscleral cyclophotocoagulation for refractory glaucoma in Asian patients. Am J Ophthalmol 124(6):797–804

    Article  PubMed  CAS  Google Scholar 

  13. Schlote T, Derse M, Rassmann K, Nicaeus T, Dietz K, Thiel HJ (2001) Efficacy and safety of contact transscleral diode laser cyclophotocoagulation for advanced glaucoma. J Glaucoma 10(4):294–301

    Article  PubMed  CAS  Google Scholar 

  14. Sivagnanavel V, Ortiz-Hurtado A, Williamson TH (2004) Diode laser trans-scleral cyclophotocoagulation in the management of glaucoma in patients with long-term intravitreal silicone oil. Eye 19(3):253–257

    Article  Google Scholar 

  15. Kumar A, Dada T, Singh RP, Kedar S (2001) Diode laser trans-scleral cyclophotocoagulation for glaucoma following silicone oil removal. Clin Exp Ophthalmol 29(4):220–224

    Article  PubMed  CAS  Google Scholar 

  16. Riedel KG, Gabel V-P, Neubauer L, Kampik A, Lund O-E (1990) Intravitreal silicone oil injection: complications and treatment of 415 consecutive patients. Graefes Arch Clin Exp Ophthalmol 228(1):19–23

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Janice J. C. Cheung.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cheung, J.J.C., Li, K.K.W. & Tang, S.W.K. Retrospective review on the outcome and safety of transscleral diode laser cyclophotocoagulation in refractory glaucoma in Chinese patients. Int Ophthalmol 39, 41–46 (2019). https://doi.org/10.1007/s10792-017-0782-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-017-0782-1

Keywords

Navigation