Skip to main content
SpringerLink
Log in

Detection of Non-Hodgkin’s Lymphoma in ovarian cortex pieces during the process of cryopreservation

  • Fertility Preservation
  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Wallace WHB, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: who is at risk and what can be offered? Lancet Oncol. 2005;6(4):209–18.

    Article  PubMed  Google Scholar 

  2. Morgan S, Anderson RA, Gourley C, Wallace WH, Spears N. How do chemotherapeutic agents damage the ovary? Hum Reprod Update. 2012;18(5):525–35.

    Article  CAS  PubMed  Google Scholar 

  3. Meirow D, Nugent D. The effects of radiotherapy and chemotherapy on female reproduction. Hum Reprod Update. 2001;7(6):535–43.

    Article  CAS  PubMed  Google Scholar 

  4. Meirow D, Dor J, Kaufman B, Shrim A, Rabinovici J, Schiff E, et al. Cortical fibrosis and blood-vessels damage in human ovaries exposed to chemotherapy. Potential mechanisms of ovarian injury. Hum Reprod. 2007;22(6):1626–33.

    Article  CAS  PubMed  Google Scholar 

  5. Jadoul P, Anckaert E, Dewandeleer A, Steffens M, Dolmans M-M, Vermylen C. Clinical and biologic evaluation of ovarian function in women treated by bone marrow transplantation for various indications during childhood or adolescence. Fertil Steril. 2011;96(1):126–33. e3.

    Article  CAS  PubMed  Google Scholar 

  6. Jadoul P, Kim SS. ISFP Practice Committee. Fertility considerations in young women with hematological malignancies. J Assist Reprod Genet. 2012;29(6):479–87.

    Article  PubMed Central  PubMed  Google Scholar 

  7. Donnez J, Dolmans M-M. Preservation of fertility in females with haematological malignancy. Br J Haematol. 2011;154(2):175–84.

    Article  PubMed  Google Scholar 

  8. Salooja N, Szydlo RM, Socie G, Rio B, Chatterjee R, Ljungman P, et al. Pregnancy outcomes after peripheral blood or bone marrow transplantation: a retrospective survey. Lancet. 2001;358(9278):271–6.

    Article  CAS  PubMed  Google Scholar 

  9. Loren AW, Mangu PB, Beck LN, Brennan L, Magdalinski AJ, Partridge AH, et al. Fertility preservation for patients with cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol Off J Am Soc Clin Oncol. 2013;31(19):2500–10.

    Article  Google Scholar 

  10. Schmidt KT, Andersen CY. ISFP Practice Committee. Recommendations for fertility preservation in patients with lymphomas. J Assist Reprod Genet. 2012;29(6):473–7.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Anderson RA, Wallace WHB, Baird DT. Ovarian cryopreservation for fertility preservation: indications and outcomes. Reproduction. 2008;136(6):681–9.

    Article  CAS  PubMed  Google Scholar 

  12. Chung K, Donnez J, Ginsburg E, Meirow D. Emergency IVF versus ovarian tissue cryopreservation: decision making in fertility preservation for female cancer patients. Fertil Steril. 2013;99(6):1534–42.

    Article  PubMed  Google Scholar 

  13. Donnez J, Dolmans M-M, Pellicer A, Diaz-Garcia C, Sanchez Serrano M, Schmidt KT, et al. Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation. Fertil Steril. 2013;99(6):1503–13.

    Article  PubMed  Google Scholar 

  14. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y. Orthotopic and heterotopic ovarian tissue transplantation. Hum Reprod Update. 2009;15(6):649–65.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  15. Bittinger SE, Nazaretian SP, Gook DA, Parmar C, Harrup RA, Stern CJ. Detection of Hodgkin lymphoma within ovarian tissue. Fertil Steril. 2011;95(2):803. e3–6.

    Article  PubMed  Google Scholar 

  16. Decanter C, Morschhauser F, Pigny P, Lefebvre C, Gallo C, Dewailly D. Anti-Müllerian hormone follow-up in young women treated by chemotherapy for lymphoma: preliminary results. Reprod Biomed Online. 2010;20(2):280–5.

    Article  CAS  PubMed  Google Scholar 

  17. Practice Committee of American Society for Reproductive Medicine. Fertility preservation in patients undergoing gonadotoxic therapy or gonadectomy: a committee opinion. Fertil Steril. 2013;100(5):1214–23.

    Article  Google Scholar 

  18. Meirow D, Hardan I, Dor J, Fridman E, Elizur S, Ra’anani H, et al. Searching for evidence of disease and malignant cell contamination in ovarian tissue stored from hematologic cancer patients. Hum Reprod. 2008;23(5):1007–13.

    Article  PubMed  Google Scholar 

  19. Dolmans M-M, Luyckx V, Donnez J, Andersen CY, Greve T. Risk of transferring malignant cells with transplanted frozen-thawed ovarian tissue. Fertil Steril. 2013;99(6):1514–22.

    Article  PubMed  Google Scholar 

  20. Meirow D, Ben Yehuda D, Prus D, Poliack A, Schenker JG, Rachmilewitz EA, et al. Ovarian tissue banking in patients with Hodgkin’s disease: is it safe? Fertil Steril. 1998;69(6):996–8.

    Article  CAS  PubMed  Google Scholar 

  21. Sonmezer M, Oktay K. Fertility preservation in female patients. Hum Reprod Update. 2004;10(3):251–66.

    Article  PubMed  Google Scholar 

  22. Shaw JM, Bowles J, Koopman P, Wood EC, Trounson AO. Fresh and cryopreserved ovarian tissue samples from donors with lymphoma transmit the cancer to graft recipients. Hum Reprod. 1996;11(8):1668–73.

    Article  CAS  PubMed  Google Scholar 

  23. Kyono K, Doshida M, Toya M, Sato Y, Akahira J, Sasano H. Potential indications for ovarian autotransplantation based on the analysis of 5,571 autopsy findings of females under the age of 40 in Japan. Fertil Steril. 2010;93(7):2429–30.

    Article  PubMed  Google Scholar 

  24. Seshadri T, Gook D, Lade S, Spencer A, Grigg A, Tiedemann K, et al. Lack of evidence of disease contamination in ovarian tissue harvested for cryopreservation from patients with Hodgkin lymphoma and analysis of factors predictive of oocyte yield. Br J Cancer. 2006;94(7):1007–10.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  25. Kim SS, Radford J, Harris M, Varley J, Rutherford AJ, Lieberman B, et al. Ovarian tissue harvested from lymphoma patients to preserve fertility may be safe for autotransplantation. Hum Reprod. 2001;16(10):2056–60.

    Article  CAS  PubMed  Google Scholar 

  26. Radford JA, Lieberman BA, Brison DR, Smith AR, Critchlow JD, Russell SA, et al. Orthotopic reimplantation of cryopreserved ovarian cortical strips after high-dose chemotherapy for Hodgkin’s lymphoma. Lancet. 2001;357(9263):1172–5.

    Article  CAS  PubMed  Google Scholar 

  27. Donnez J, Dolmans MM, Demylle D, Jadoul P, Pirard C, Squifflet J, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet. 2004;364(9443):1405–10.

    Article  CAS  PubMed  Google Scholar 

  28. Schmidt KLT, Andersen CY, Loft A, Byskov AG, Ernst E, Andersen AN. Follow-up of ovarian function post-chemotherapy following ovarian cryopreservation and transplantation. Hum Reprod. 2005;20(12):3539–46.

    Article  CAS  PubMed  Google Scholar 

  29. Demeestere I, Simon P, Buxant F, Robin V, Fernandez SA, Centner J, et al. Ovarian function and spontaneous pregnancy after combined heterotopic and orthotopic cryopreserved ovarian tissue transplantation in a patient previously treated with bone marrow transplantation: case report. Hum Reprod. 2006;21(8):2010–4.

    Article  PubMed  Google Scholar 

  30. Demeestere I, Simon P, Emiliani S, Delbaere A, Englert Y. Fertility preservation: successful transplantation of cryopreserved ovarian tissue in a young patient previously treated for Hodgkin’s disease. The oncologist. 2007;12(12):1437–42.

    Article  PubMed  Google Scholar 

  31. Dolmans M-M, Donnez J, Camboni A, Demylle D, Amorim C, Van Langendonckt A, et al. IVF outcome in patients with orthotopically transplanted ovarian tissue. Hum Reprod. 2009;24(11):2778–87.

    Article  PubMed  Google Scholar 

  32. Schmidt KT, Rosendahl M, Ernst E, Loft A, Andersen AN, Dueholm M, et al. Autotransplantation of cryopreserved ovarian tissue in 12 women with chemotherapy-induced premature ovarian failure: the Danish experience. Fertil Steril. 2011;95(2):695–701.

    Article  PubMed  Google Scholar 

  33. Andersen CY, Rosendahl M, Byskov AG, Loft A, Ottosen C, Dueholm M, et al. Two successful pregnancies following autotransplantation of frozen/thawed ovarian tissue. Hum Reprod. 2008;23(10):2266–72.

    Article  PubMed  Google Scholar 

  34. Dittrich R, Lotz L, Keck G, Hoffmann I, Mueller A, Beckmann MW, et al. Live birth after ovarian tissue autotransplantation following overnight transportation before cryopreservation. Fertil Steril. 2012;97(2):387–90.

    Article  PubMed  Google Scholar 

  35. Faris JE, LaCasce AS. Primary mediastinal large B-cell lymphoma. Clin Adv Hematol Oncol HO. 2009;7(2):125–33.

    Google Scholar 

  36. Johnson PWM, Davies AJ. Primary mediastinal B-cell lymphoma. Hematol Educ Program Am Soc Hematol Am Soc Hematol Educ Program. 2008;349–58.

  37. Meirow D, Levron J, Eldar-Geva T, Hardan I, Fridman E, Zalel Y, et al. Pregnancy after transplantation of cryopreserved ovarian tissue in a patient with ovarian failure after chemotherapy. N Engl J Med. 2005;353(3):318–21.

    Article  CAS  PubMed  Google Scholar 

  38. Meirow D, Biederman H, Anderson RA, Wallace WHB. Toxicity of chemotherapy and radiation on female reproduction. Clin Obstet Gynecol. 2010;53(4):727–39.

    Article  PubMed  Google Scholar 

  39. Smitz J, Dolmans MM, Donnez J, Fortune JE, Hovatta O, Jewgenow K, et al. Current achievements and future research directions in ovarian tissue culture, in vitro follicle development and transplantation: implications for fertility preservation. Hum Reprod Update. 2010;16(4):395–414.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  40. Vanacker J, Luyckx V, Amorim C, Dolmans M-M, Van Langendonckt A, Donnez J. Should we isolate human preantral follicles before or after cryopreservation of ovarian tissue? Fertil Steril. 2013;99(5):1363–8. e2.

    Article  PubMed  Google Scholar 

  41. Amorim CA, Van Langendonckt A, David A, Dolmans M-M, Donnez J. Survival of human pre-antral follicles after cryopreservation of ovarian tissue, follicular isolation and in vitro culture in a calcium alginate matrix. Hum Reprod. 2009;24(1):92–9.

    Article  CAS  PubMed  Google Scholar 

  42. Hovatta O. Cryopreservation and culture of human ovarian cortical tissue containing early follicles. Eur J Obstet Gynecol Reprod Biol. 2004;113 Suppl 1:S50–54.

    Article  PubMed  Google Scholar 

  43. Telfer EE, McLaughlin M. In vitro development of ovarian follicles. Semin Reprod Med. 2011;29(1):15–23.

    Article  CAS  PubMed  Google Scholar 

  44. Berwanger AL, Finet A, El Hachem H, le Parco S, Hesters L, Grynberg M. New trends in female fertility preservation: in vitro maturation of oocytes. Future Oncol. 2012;8(12):1567–73.

    Article  CAS  PubMed  Google Scholar 

  45. Grynberg M, El Hachem H, de Bantel A, Benard J, le Parco S, Fanchin R. In vitro maturation of oocytes: uncommon indications. Fertil Steril. 2013;99(5):1182–8.

    Article  CAS  PubMed  Google Scholar 

  46. Chian R-C, Uzelac PS, Nargund G. In vitro maturation of human immature oocytes for fertility preservation. Fertil Steril. 2013;99(5):1173–81.

    Article  CAS  PubMed  Google Scholar 

  47. De Ziegler D, Streuli I, Vasilopoulos I, Decanter C, This P, Chapron C. Cancer and fecundity issues mandate a multidisciplinary approach. Fertil Steril. 2010;93(3):691–6.

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

No conflict of interest.

Author information

Authors and Affiliations

  1. Service de Gynécologie Endocrinienne et de Médecine de la Reproduction, Hôpital Jeanne de Flandre, CHRU de Lille, 3 avenue Eugène Avinée, 59037, Lille Cedex, France

    Héloïse Gronier, Geoffroy Robin, Catherine Lefebvre & Christine Decanter

  2. Service d’Hématologie Clinique et des Maladies du Sang, Hôpital Claude Huriez, Rue Michel Polonovski, 59037, Lille Cedex, France

    Louis Terriou & Franck Morschhauser

  3. Service d’Anatomie et de Cytopathologie, Hôpital Claude Huriez, Rue Michel Polonovski, 59037, Lille Cedex, France

    Agnès Wacrenier

  4. Service de Biologie de la Reproduction, Hôpital Jeanne de Flandre, CHRU de Lille, 3 avenue Eugène Avinée, 59037, Lille Cedex, France

    Brigitte Leroy-Martin

  5. Service de Chirurgie Gynécologique et Obstétrique, Hôpital Jeanne de Flandre, CHRU de Lille, 3 avenue Eugène Avinée, 59037, Lille Cedex, France

    Denis Vinatier

Authors
  1. Héloïse Gronier
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Louis Terriou
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Geoffroy Robin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Agnès Wacrenier
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Brigitte Leroy-Martin
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Catherine Lefebvre
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Denis Vinatier
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Franck Morschhauser
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Christine Decanter
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Héloïse Gronier.

Additional information

Capsule Recent data regarding the potential ovarian involvement by lymphoma cells urge caution when a reimplantation of ovarian tissue is planed. Patients have to be rigorously informed about this risk before the decision of ovarian removal or auto-transplantation.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gronier, H., Terriou, L., Robin, G. et al. Detection of Non-Hodgkin’s Lymphoma in ovarian cortex pieces during the process of cryopreservation. J Assist Reprod Genet 31, 1251–1255 (2014). https://doi.org/10.1007/s10815-014-0292-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10815-014-0292-2

Keywords

Search

Navigation