Skip to main content
Log in

Quality of life in older people with atrial fibrillation

  • Published:
Journal of Interventional Cardiac Electrophysiology Aims and scope Submit manuscript

Abstract

This review summarises the literature on quality of life in patients with atrial fibrillation. Since atrial fibrillation is predominantly a disease of maturity, the majority of studies examining quality of life in this patient population have been conducted in older adults people (aged ≥65 years). Almost all studies have demonstrated poorer quality of life among patients with atrial fibrillation compared to age-matched general populations. Rate-control and rhythm-control strategies in highly symptomatic patients have revealed significant improvements in quality of life following the interventions, presumably as a result of the immediate relief of symptoms. Further, randomised controlled trials of rate- versus rhythm-control strategies have shown that some aspects of quality of life improve significantly following either intervention and that neither rate nor rhythm-control is superior in increasing quality of life. Control of the heart rate, rather than restoring sinus rhythm, appears to be associated with better quality of life in more domains.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Go, A. S., Hylek, E. M., Phillips, K. A., Chang, Y., Henault, L. E., Selby, J. V., et al. (2001). Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. Journal of the American Medical Association, 285, 2370–2375.

    Article  PubMed  CAS  Google Scholar 

  2. Miyasaka, Y., Barnes, M. E., Gersh, B. J., Cha, S. S., Bailey, K. R., Abhayaratna, W. P., et al. (2006). Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence. Circulation, 114, 119–125.

    Article  PubMed  Google Scholar 

  3. World Health Organisation (1947). The constitution of the World Health Organisation. WHO Chronicle, 1, 29.

    Google Scholar 

  4. Sanders, C., Egger, M., Donovan, J., Tallon, D., & Frankel, S. (1998). Reporting on quality of life in randomised controlled trials: bibliographic study. BMJ (Clinical Research Ed.), 317, 1191–1194.

    CAS  Google Scholar 

  5. Stewart, A. L., Hays, R. D., & Ware Jr., J. E. (1988). The MOS short-form general health survey. Reliability and validity in a patient population. Medical Care, 26, 724–735.

    Article  PubMed  CAS  Google Scholar 

  6. Badia, X., Arribas, F., Ormaetxe, J. M., Peinado, R., & de Los Terreros, M. S. (2007). Development of a questionnaire to measure health-related quality of life (HRQoL) in patients with atrial fibrillation (AF-QoL). Health and Quality of Life Outcomes, 5, 37.

    Article  PubMed  Google Scholar 

  7. National Collaborating Centre for Chronic Conditions. Atrial fibrillation: national clinical guideline for management in primary and secondary care. London: Royal College of Physicians 2006; http://www.nice.org.uk/guidance/CG36.

  8. Fuster, V., Ryden, L. E., Cannom, D. S., Crijns, H. J., Curtis, A. B., Ellenbogen, K. A., et al. (2006). Committee for Practice Guidelines, European Society of Cardiology; European Heart Rhythm Association; Heart Rhythm Society. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation-executive summary: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients with Atrial Fibrillation). European Heart Journal, 27, 1979–2030.

    Article  PubMed  Google Scholar 

  9. Thrall, G., Lane, D., Carroll, D., & Lip, G. Y. H. (2006). Quality of life in patients with atrial fibrillation: a systematic review. American Journal of Medicine, 119(448), e1–19.

    PubMed  Google Scholar 

  10. Luderitz, B., & Jung, W. (2000). Quality of life in patients with atrial fibrillation. Archives of Internal Medicine, 160, 1749–1757.

    Article  PubMed  CAS  Google Scholar 

  11. Jenkins, L. S., Brodsky, M., Schron, E., Chung, M., Rocco Jr, T., Lader, E., et al. (2005). for the AFFIRM investigators. Quality of life in atrial fibrillation: the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study. American Heart Journal, 149, 112–120.

    Article  PubMed  Google Scholar 

  12. Dantas, G. C., Thompson, B. V., Manson, J. A., Tracy, C. S., & Upshur, R. E. (2004). Patients’ perspectives on taking warfarin: qualitative study in family practice. BMC Family Practice, 5, 15.

    Article  PubMed  Google Scholar 

  13. Das, A. K., Willcoxson, P. D., Corrado, O. J., & West, R. M. (2007). The impact of long-term warfarin on the quality of life of elderly people with atrial fibrillation. Age and Ageing, 36, 95–97.

    Article  PubMed  Google Scholar 

  14. Howes, C. J., Reid, M. C., Brandt, C., Ruo, B., Yerkey, M. W., Prasad, B., et al. (2001). Exercise tolerance and quality of life in elderly patients with chronic atrial fibrillation. Journal of Cardiovascular Pharmacology and Therapeutics, 6, 23–29.

    Article  PubMed  CAS  Google Scholar 

  15. Paquette, M., Roy, D., Talajic, M., Newman, D., Couturier, A., Yang, C., et al. (2000). Role of gender and personality on quality-of-life impairment in intermittent atrial fibrillation. The American Journal of Cardiology, 86, 764–768.

    Article  PubMed  CAS  Google Scholar 

  16. Kang, Y., & Bahler, R. (2003). Health related quality of life in patients newly diagnosed with atrial fibrillation. European Journal of Cardiovascular Nursing, 3, 71–76.

    Article  Google Scholar 

  17. Gronefeld, G. C., Lilienthal, J., Kuck, K. H., & Hohnloser, S. H. (2003). Pharmacological Intervention in Atrial Fibrillation (PIAF) Study investigators. Impact of rate versus rhythm control on quality of life in patients with persistent atrial fibrillation. Results from a prospective randomized study. European Heart Journal, 24, 1430–1436.

    Article  PubMed  Google Scholar 

  18. Hagens, V. E., Ranchor, A. V., Van Sonderen, E., Bosker, H. A., Kamp, O., Tijssen, J. G., et al. (2004). Effect of rate or rhythm control on quality of life in persistent atrial fibrillation. Results from the Rate Control Versus Electrical Cardioversion (RACE) study. Journal of the American College of Cardiology, 43, 241–247.

    Article  PubMed  Google Scholar 

  19. Carlsson, J., Miketic, S., Windeler, J., Cuneo, A., Haun, S., Micus, S., et al. (2003). Randomized trial of rate-control versus rhythm-control in persistent atrial fibrillation. Journal of the American College of Cardiology, 41, 1690–1696.

    Article  PubMed  Google Scholar 

  20. Reynolds, M. R., Lavelle, T., Essebag, V., Cohen, D. J., & Zimetbaum, P. (2006). Influence of age, sex, and atrial fibrillation recurrence on quality of life outcomes in a population of patients with new-onset atrial fibrillation: the Fibrillation Registry Assessing Costs, Therapies, Adverse events and Lifestyle (FRACTAL) study. American Heart Journal, 152, 1097–1103.

    Article  PubMed  Google Scholar 

  21. Wood, M. A., Brown-Mahoney, C., Kay, G. N., & Ellenbogen, K. A. (2000). Clinical outcomes after ablation and pacing therapy for atrial fibrillation: a meta-analysis. Circulation, 101, 1138–1144.

    PubMed  CAS  Google Scholar 

  22. Wazni, O. M., Marrouche, N. F., Martin, D. O., Verma, A., Bhargava, M., Saliba, W., et al. (2005). Radiofrequency ablation vs. antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation: a randomized trial. Journal of the American Medical Association, 293, 2634–2640.

    Article  PubMed  CAS  Google Scholar 

  23. Pappone, C., Rosanio, S., Augello, G., Gallus, G., Vicedomini, G., Mazzone, P., et al. (2003). Mortality, morbidity, and quality of life after circumferential pulmonary vein ablation for atrial fibrillation: outcomes from a controlled nonrandomized long-term study. Journal of the American College of Cardiology, 42, 185–197.

    Article  PubMed  Google Scholar 

  24. Berkowitsch, A., Neumann, T., Kurzidim, K., Reiner, C., Kuniss, M., Siemon, G., et al. (2003). Comparison of generic health survey SF-36 and arrhythmia related symptom severity check list in relation to post-ablation recurrence. Europace, 5, 351–355.

    Article  PubMed  CAS  Google Scholar 

  25. Hindricks, G., Piorkowski, C., Tanner, H., Kobza, R., Gerd-Li, J. H., Carbucicchio, C., et al. (2005). Perception of atrial fibrillation before and after radiofrequency catheter ablation: Relevance of asymptomatic arrhythmia recurrence. Circulation, 112, 307–313.

    Article  PubMed  Google Scholar 

  26. Thrall, G., Lip, G. Y., Carroll, D., & Lane, D. (2007). Depression, anxiety and quality of life in patients with atrial fibrillation. Chest, 132, 1259–1264.

    Article  PubMed  Google Scholar 

  27. Lane, D., Carroll, D., Ring, C., Beevers, D. G., & Lip, G. Y. (2001). Mortality and quality of life 12 months after myocardial infarction: effects of depression and anxiety. Psychosomatic Medicine, 63, 221–230.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gregory Y. H. Lip.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lane, D.A., Lip, G.Y.H. Quality of life in older people with atrial fibrillation. J Interv Card Electrophysiol 25, 37–42 (2009). https://doi.org/10.1007/s10840-008-9318-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10840-008-9318-y

Keywords

Navigation