Abstract
A lifecourse perspective is key for understanding and interpreting racial and ethnic patterns in neuropsychological test performance. In this article, we discuss contextual factors that shape the environmental conditions encountered by racial and ethnic minorities in the United States, in particular African-Americans. These conditions include geographic segregation at the level of regions, metropolitan areas, and neighborhoods; intra- and inter-national migration patterns; socioeconomic position, including financial resources, and occupational and educational opportunities; discrimination; and group resources. Each of these exposures sets in course a cascade of individual mediators that ultimately manifest in neuropsychological outcomes. The physiological and behavioral consequences of these pathways likely accumulate across the lifecourse. We focus on cognitive aging, although the processes discussed here begin in infancy and likely influence cognitive outcomes throughout life from childhood into old age. A lifecourse framework can help inform clinical encounters, neuropsychological research, and surveillance regarding the population prevalence of cognitive impairments.
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Anonymous (2005). Regional and racial differences in prevalence of stroke–23 states and District of Columbia, 2003. MMWR Morb Mortal Wkly Rep, 54(19), 481–484.
Abbott, R., White, L., et al. (1998). Height as a marker of childhood development and late-life cognitive function: the Honolulu-Asia Aging Study. Pediatrics, 102(3 Pt 1), 602–609.
Acolet, D., Modi, N., et al. (1993). Changes in plasma cortisol and catecholamine concentrations in response to massage in preterm infants. Archives of Disease in Childhood, 68(1 Spec No), 29–31.
Albert, M. S., Jones, K., et al. (1995). Predictors of cognitive change in older persons: MacArthur studies of successful aging. Psychology and Aging, 10(4), 578–589.
Alt, J. E. (1994). The impact of the voting rights act on black and white voter registration in the South. In C. Davidson, and B. Grofman (eds.), Quiet Revolution in the South: The Impact of the Voting Rights Act, 1965–1990 (pp. 351–377). Princeton University Press.
Anstey, K., & Christensen, H. (2000). Education, activity, health, blood pressure and apolipoprotein E as predictors of cognitive change in old age: a review. Gerontology, 46(3), 163–177.
Ardila, A., & Rosselli, M. (1989). Neuropsychological characteristics of normal aging. Developmental Neuropsychology, 5, 307–320.
Ardila, A., Rosselli, M., et al. (1994). Neuropsychological Evaluation of the Spanish Speaker. New York: Plenum.
Ardila, A., Rosselli, M., et al. (2000). Syntactic comprehension, verbal memory, and calculation abilities in Spanish-English bilinguals. Applied Neuropsychology, 7, 3–16.
Ball, K., Berch, D. B., et al. (2002). Effects of cognitive training interventions with older adults—A randomized controlled trial. Jama—Journal of the American Medical Association, 288(18), 2271–2281.
Bao, W. H., Srinivasan, S. R., et al. (1995). The relation of parental cardiovascular-disease to risk-factors in children and young-adults—the Bogalusa Heart-Study. Circulation, 91(2), 365–371.
Barker, D. J. (1990). The fetal and infant origins of adult disease. BMJ, 301(6761), 1111.
Barker, D. J. (1999). Fetal origins of cardiovascular disease. Annals of Medicine, 31(Suppl 1), 3–6.
Barker, D. J., & Martyn, C. (1992). The maternal and fetal origins of cardiovascular disease.” Journal of Epidemiology and Community Health, 46, 8–11.
Barnes, L. L., de Leon, C. F. M., et al. (2004). Social resources and cognitive decline in a population of older African Americans and whites. Neurology, 63(12), 2322–2326.
Barona, A., Reynolds, C. R., et al. (1984). A demographically based index of premorbid intelligence for the Wais-R. Journal of Consulting and Clinical Psychology, 52(5), 885–887.
Bassuk, S. S., Glass, T. A., et al. (1999). Social disengagement and incident cognitive decline in community-dwelling elderly persons. Annals of Internal Medicine, 131(3), 165–173.
Bennett, D. A., Schneider, J. A., et al. (2006). The effect of social networks on the relation between Alzheimer’s disease pathology and level of cognitive function in old people: a longitudinal cohort study. Lancet Neurology, 5(5), 406–412.
Bennett, G. G., & Merritt, M. M., et al. (2004). Perceived racism and affective responses to ambiguous interpersonal interactions among African American Men. American Behavioral Scientist, 47, 963.
Benuskova, L., Diamond, M. E., et al. (1994). Dynamic synaptic modification threshold: computational model of experience-dependent plasticity in adult rat barrel cortex. Proceedings of the National Academy of Sciences of the United States of America, 91(11), 4791–4795.
Berenson, G., Srinivasan, S., et al. (2006). Racial (Black–White) contrasts of risk for hypertensive disease in youth have implications for preventive care: The Bogalusa Heart Study. Ethnicity & Disease, 16(3), S2–S9.
Berkman, L. F. (2000). Which influences cognitive function: living alone or being alone?, editorial. The Lancet, 355, 1291–1292.
Berkman, L. F., & Glass, T. (2000). Social integration, social networks, social support, and health. In L. F. Berkman, & I. Kawachi (Eds.), Social Epidemiology (pp. 137–173). New York: Oxford University Press.
Berkman, L. F., & Macintyre, S. (1997). The measurement of social class in health studies: old measures and new formulations. IARC Scientific Publications (Lyon), 138, 51–64.
Bertrand, M., & Mullainathan, S. (2004). Are Emily and Greg more employable than Lakisha and Jamal? A field experiment on labor market discrimination. The American Economic Review, 94(4), 991–1013.
Bialystok, E., Craik, F. I. M., et al. (2004). Bilingualism, aging, and cognitive control: Evidence from the Simon task. Psychology and Aging, 19(2), 290–303.
Bialystok, E., Craik, F. I. M., et al. (2006). Executive control in a modified antisaccade task: Effects of aging and bilingualism. Journal of Experimental Psychology–Learning Memory and Cognition, 32(6), 1341–1354.
Bobo, L. (2000). Racial attitudes and relations at the close of the twentieth century. In N. Smelser, W. Wilson, & F. Mitchell (Eds.), America Becoming: Racial Trends and Their Consequences (vol. 1, pp. 264–301). Washington DC: National Research Council, National Academy Press.
Bolen, J. C., Rhodes, L., et al. (2000). State-specific prevalence of selected health behaviors, by race and ethnicity—Behavioral Risk Factor Surveillance System, 1997. MMWR CDC Surveillance Summaries, 49(2), 1–60.
Brand, C. (1987). Intelligence-testing—Bryter Still and Bryter. Nature, 328(6126), 110–110.
Braveman, P. A., Cubbin, C., et al. (2005). Socioeconomic status in health research - One size does not fit all. Jama-Journal of the American Medical Association, 294(22), 2879–2888.
Brayne, C., & Calloway, P. (1990). The association of education and socioeconomic status with the Mini Mental State Examination and the clinical diagnosis of dementia in elderly people. Age & Ageing, 19(2), 91–96.
Breslau, J., Aguilar-Gaxiola, S., et al. (2005). Specifying race–ethnic differences in risk for psychiatric disorder in a USA national sample. Psychological Medicine, 36(01), 57–68.
Breslau, J., & Kendler, K. S., et al. (2004). Lifetime risk and persistence of psychiatric disorders across ethnic groups in the United States, Cambridge University Press. 35: 317–327.
Brodkin, K. (2004). How Did Jews Become White Folks? And What That Says About Race in America. New Brunswick, NJ: Routledge.
Brown, L., & Pollittt, E. (1996). Malnutrition, poverty and intellectual development. Scientific American, 274, 38–43.
Butler, S. M., Ashford, J. W., et al. (1996). Age, education, and changes in the Mini-Mental State Exam scores of older women: findings from the Nun Study. Journal of the American Geriatrics Society, 44(6), 675–681.
Byrd, D. A., Sanchez, D., et al. (2005). Neuropsychological test performance among Caribbean-born and U.S.-born African American Elderly: The role of age, education and reading level. Journal of Clinical and Experimental Neuropsychology, 27(8), 1056–1069.
Cagney, K. A., Browning, C. R., et al. (2007). The Latino Paradox in neighborhood context: The case of asthma and other respiratory conditions. American Journal of Public Health, 97(5), 919.
Callahan, C. M., & Hall, K. S., et al. (1996). Relationship of age, education, and occupation with dementia among a community-based sample of African Americans. Archives of Neurology, 53(2), 134–140.
Card, D., & Krueger, A. (1996). School resources and student outcomes: An overview of the literature and new evidence from North and South Carolina. Journal of Economic Perspectives, 10(4), 31–50.
Cerhan, J. R., Folsom, A. R., et al. (1998). Correlates of cognitive function in middle-aged adults. Gerontology, 44(2), 95–105.
Charles, C. Z. (2003). The dynamics of racial residential segregation. Annual Review of Sociology, 29(1), 167–207.
Charles, C. Z., Dinwiddie, G., et al. (2004). The continuing consequences of segregation: Family stress and college academic performance. Social Science Quarterly, 85(5), 1353–1373.
Chatters, L. M. (2000). Religion and health: Public health research and practice. Annual Review of Public Health, 21(1), 335–367.
Cheung, Y. B., Low, L., et al. (2000). Fetal growth and early postnatal growth are related to blood pressure in adults. Hypertension, 36(5), 795–800.
Cho, Y., Frisbie, W. P., et al. (2004). Nativity, duration of residence, and the health of Hispanic adults in the United States. International Migration Review, 38(1), 184–211.
Christensen, H., Korten, A. E., et al. (1997). Education and decline in cognitive performance: compensatory but not protective. International Journal of Geriatric Psychiatry, 12(3), 323–330.
Clark, R., & Anderson, N. B., et al. (1999). Racism as a Stressor for African Americans: A Biopsychosocial Model. The American Psychologist, 54, 805–816.
Conley, D., & Yeung, W. J. (2005). Black–white differences in occupational prestige—Their impact on child development. American Behavioral Scientist, 48(9), 1229–1249.
Corrigan, P. W. (2002). The Paradox of Self-Stigma and Mental Illness. Blackwell Synergy. 9: 35–53.
Cotman, C. W., & Berchtold, N. C. (2002). Exercise: a behavioral intervention to enhance brain health and plasticity. Trends in Neurosciences, 25(6), 295–301.
Cramer, S. C. (1999). Stroke recovery. Lessons from functional MR imaging and other methods of human brain mapping. Physical Medicine & Rehabilitation Clinics of North America, 10(4), 875–886, ix.
Cramer, S. C. (2000). Stroke recovery: how the computer reprograms itself. Neuronal plasticity: the key to stroke recovery. Kananskis, Alberta, Canada, 19–22 March 2000. Molecular Medicine Today, 6(8), 301–303.
Cramer, S. C., Moore, C. I., et al. (2000). A pilot study of somatotopic mapping after cortical infarct. Stroke, 31(3), 668–671.
Crane, P. K., Belle, G., et al. (2004). Test bias in a cognitive test: Differential item functioning in the CASI. Statistics in Medicine, 23(2), 241–256.
Cutler, D. M., Miller, G., et al. (2007). Economics of health and mortality special feature: Evidence on early-life income and late-life health from America’s Dust Bowl era. Proceedings of the National Academy of Sciences, 104(33), 13244–13249.
David, R. J., & Collins, J. W. (1997). Differing birth weight among infants of US-Born Blacks, African-Born Blacks, and US-Born Whites. New England Journal of Medicine, 337(17), 1209.
de la Torre, J. C. (2000). Critically attained threshold of cerebral hypoperfusion: can it cause Alzheimer’s disease? Annals of the New York Academy of Sciences, 903, 424–436.
De Ronchi, D., & Fratiglioni, L., et al. (1998). The effect of education on dementia occurrence in an Italian population with middle to high socioeconomic status. Neurology, 50(5), 1231–1238.
De Stavola, B. L., Nitsch, D., et al. (2006). Statistical issues in life course epidemiology. American Journal of Epidemiology, 163(1), 84–96.
Deary, I. J., & Batty, G. D. (2007). Cognitive epidemiology. J Epidemiol Community Health, 61(5), 378–384.
Del Ser, T., Hachinski, V., et al. (1999). An autopsy-verified study of the effect of education on degenerative dementia. Brain, 122(Pt 12), 2309–2319.
Diamond, M. E., Armstrong-James, M., et al. (1993). Experience-dependent plasticity in adult rat barrel cortex. Proceedings of the National Academy of Sciences of the United States of America, 90(5), 2082–2086.
Dovidio, J. F., & Kawakami, K., et al. (2002). Implicit and explicit prejudice and interracial interaction. Journal of Personality and Social Psychology, 82, 62–68.
Draganski, B., Gaser, C., et al. (2004). Neuroplasticity: Changes in grey matter induced by training. Nature, 427, 311–312.
Duncan, G. J., Brooksgunn, J., et al. (1994). Economic deprivation and early-childhood development. Child Development, 65(2), 296–318.
Dunlop, D. D., Song, J., et al. (2003). Racial/ethnic differences in rates of depression among preretirement adults. American Public Health Association, 93, 1945–1952.
Edland, S. D., Xu, Y., et al. (2002). Total intracranial volume: Normative values and lack of association with Alzheimer’s disease. Neurology, 59(2), 272–274.
Eriksson, J. G., Forsen, T., et al. (2001). Early growth and coronary heart disease in later life: longitudinal study. BMJ, 322(7292), 949–953.
Ertel, K., Glymour, M., et al. (2008). Effects of social integration on preserving memory function in a nationally representative US elderly population. American Journal of Public Health, 98(7), 1215–1220.
Eschbach, K., & Ostir, G. V., et al. (2004). Neighborhood context and mortality among older Mexican Americans: Is there a Barrio advantage? American Journal of Public Health, 94, 1807–1812.
Espino, D. V., Lichtenstein, M. J., et al. (2001). Ethnic differences in Mini-Mental State Examination (MMSE) scores: Where you live makes a difference. Journal of the American Geriatrics Society, 49(5), 538–548.
Evans, D. A., Hebert, L. E., et al. (1997). Education and other measures of socioeconomic status and risk of incident Alzheimer disease in a defined population of older persons. Archives of Neurology, 54(11), 1399–1405.
Fang, J., Madhavan, S., et al. (1996). The association between birthplace and mortality from cardiovascular causes among black and white residents of New York City. New England Journal of Medicine, 335(21), 1545–1551.
Farmer, M. E., Kittner, S. J., et al. (1995). Education and change in cognitive function. The epidemiologic catchment area study. Annals of Epidemiology, 5(1), 1–7.
Ferguson, R. F. (2003). Teachers’ perceptions and expectations and the black-white test score gap. Urban Education, 38(4), 460.
Flynn, J. R. (1984). The mean IQ of Americans—massive gains 1932 to 1978. Psychological Bulletin, 95(1), 29–51.
Fontbonne, A., Berr, C., et al. (2001). Changes in cognitive abilities over a 4-year period are unfavorably affected in elderly diabetic subjects: Results of the Epidemiology of Vascular Aging Study. Diabetes Care, 24(2), 366–370.
Frantz, C. M., Cuddy, A. J. C., et al. (2004). A threat in the computer: The race implicit association test as a stereotype threat experience. Personality and Social Psychology Bulletin, 30(12), 1611.
Fratiglioni, L., Grut, M., et al. (1991). Prevalence of Alzheimer’s disease and other dementias in an elderly urban population: relationship with age, sex, and education. Neurology, 41(12), 1886–1892.
Fratiglioni, L., & Wang, H.-X., et al. (2000). Influence of social network on occurrence of dementia: a community-based longitudinal study. The Lancet, 355, 1315–1319.
Freedman, V. A., Aykan, H., et al. (2001). Aggregate changes in severe cognitive impairment among older Americans: 1993 and 1998. Journals of Gerontology Series B, Psychological Sciences & Social Sciences, 56(2), S100–S111.
Freedman, V. A., Martin, L. G., et al. (2002). Recent trends in disability and functioning among in the United States - A systematic review. Jama-Journal of the American Medical Association, 288(24), 3137–3146.
Fried, L. P., Carlson, M. C., et al. (2004). A social model for health promotion for an aging population: Initial evidence on the experience corps model. Journal of Urban Health-Bulletin of the New York Academy of Medicine, 81(1), 64–78.
Friedland, R. P. (1993). Epidemiology, education, and the ecology of Alzheimer’s disease. Neurology, 43(2), 246–249.
Friedland, R. P., Fritsch, T., et al. (2001). Patients with Alzheimer’s disease have reduced activities in midlife compared with healthy control-group members. Proceedings of the National Academy of Sciences of the United States of America, 98(6), 3440–3445.
Gale, C. R., Walton, S., et al. (2003). Foetal and postnatal head growth and risk of cognitive decline in old age. Brain, 126, 2273–2278.
Gallo, L. C., & Matthews, K. A. (2003). Understanding the association between socioeconomic status and physical health: Do negative emotions play a role? Psychological Bulletin, 129(1), 10–51.
Galobardes, B., Shaw, M., et al. (2006). Indicators of socioeconomic position (part 1). Journal of Epidemiology and Community Health, 60(1), 7–12.
Gatz, M., Svedberg, P., et al. (2001). Education and the risk of Alzheimer’s disease: findings from the study of dementia in Swedish twins. Journals of Gerontology Series B-Psychological Sciences & Social Sciences, 56(5), 292–300.
Geronimus, A. T. (1992). The weathering hypothesis and the health of African-American women and infants: evidence and speculations. Ethnicity and Disease, 2(3), 207–221.
Geronimus, A. T., Hicken, M., et al. (2006). Weathering and age patterns of allostatic load scores among blacks and whites in the United States. AJPH, 96(5), 826–833.
Gianaros, P. J., Jennings, J. R., et al. (2007). Prospective reports of chronic life stress predict decreased grey matter volume in the hippocampus. Neuroimage, 35(2), 795–803.
Giraud, A. L., Price, C. J., et al. (2001). Functional plasticity of language-related brain areas after cochlear implantation. Brain, 124(Pt 7), 1307–1316.
Glymour, M. M. (2007). Commentary: Selected samples and nebulous measures: some methodological difficulties in life-course epidemiology. International Journal of Epidemiology, 36(3), 566–568.
Glymour, M. M., Avendano, M. P., et al. (2007). Is the stroke belt worn from childhood? Risk of first stroke and state of residence in childhood and adulthood. Stroke, 38(9), 2415–2421.
Glymour, M. M., Kawachi, I., et al. (2008). Does childhood schooling affect old age memory or mental status? Using state schooling laws as natural experiments. Journal of Epidemiology and Community Health, 62(6), 532–537.
Godfrey, K. M., & Barker, D. J. (2000). Fetal nutrition and adult disease. American Journal of Clinical Nutrition, 71(5 Suppl), 1344S–1352S.
Goff, P. A. (2005). The space between us: Stereotype threat for Whites in interracial domains. Journal of Personality and Social Psychology, Stanford University.
González, H. M., Whitfield, K. E., et al. (2007). Modified-symbol digit modalities test for African Americans, Caribbean Black Americans, and non-Latino Whites: Nationally representative normative data from the National Survey of American Life. Archives of Clinical Neuropsychology, 22(5), 605–613.
Gortmaker, S. L., & Wise, P. H. (1997). The first injustice: Socioeconomic disparities, health services technology, and infant mortality. Annual Reviews in Sociology, 23(1), 147–170.
Gottfredson, L. S. (2005). What if the hereditarian hypothesis is true? Psychology Public Policy and Law, 11(2), 311–319.
Graves, A. B., Mortimer, J. A., et al. (1996). Head circumference as a measure of cognitive reserve. Association with severity of impairment in Alzheimer’s disease. British Journal of Psychiatry, 169(1), 86–92.
Graves, A. B., Mortimer, J. A., et al. (2001). Head circumference and incident Alzheimer’s disease - Modification by apolipoprotein E. Neurology, 57(8), 1453–1460.
Gray, S. L., Lai, K. V., et al. (1999). Drug-induced cognition disorders in the elderly: Incidence, prevention and management. Drug Safety, 21, 101–122.
Greenberg, M., & Schneider, D. (1992). Region of birth and mortality of blacks in the United-States. International Journal of Epidemiology, 21(2), 324–328.
Greenough, W., & Black, J. (1992). Induction of brain structure by experience: substrates for cognitive development. In M. Gunnar, & C. Nelson (Eds.), Minnesota Symposia on Child Psychology: Developmental Neuroscience (vol. 24, pp. 155–200). Hillsdale, NJ: Erlbaum.
Gregg, E. W., Yaffe, K., et al. (2000). Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Archives of Internal Medicine, 160(2), 174–180.
Gump, B. B., Matthews, K. A., et al. (1999). Modeling relationships among socioeconomic status, hostility, cardiovascular reactivity, and left ventricular mass in African American and White children. Health Psychology, 18(2), 140–150.
Guo, G., & Harris, K. M. (2000). The mechanisms mediating the effects of poverty on children’s intellectual development. Demography, 37(4), 431–447.
Haas, S. (2007a). The long-term effects of poor childhood health: an assessment and application of retrospective reports. Demography, 44(1), 113–135.
Haas, S. (2007b). Trajectories of functional health: The ‘long arm’ of childhood health and socioeconomic factors. Social Science and Medicine.
Habeck, C., Hilton, H. J., et al. (2003). Relation of cognitive reserve and task performance to expression of regional covariance networks in an event-related fMRI study of nonverbal memory. Neuroimage, 20(3), 1723–1733.
Hachinski, V. (2007). Stroke and vascular cognitive impairment: A transdisciplinary, translational and transactional approach. Stroke, 38(4), 1396–1403.
Hachinski, V., & Munoz, D. (2000). Vascular factors in cognitive impairment—where are we now? Annals of the New York Academy of Sciences, 903, 1–5.
Hajjar, I., & Kotchen, T. (2003). Regional variations of blood pressure in the united states are associated with regional variations in dietary intakes: The NHANES-III data. Journal of Nutrition, 133(1), 211–214.
Hall, K., Gureje, O., et al. (1998). Risk factors and Alzheimer’s disease: a comparative study of two communities. Australian and New Zealand Journal of Psychiatry, 32(5), 698–706.
Hall, K. S., Gao, S., et al. (2000). Low education and childhood rural residence Risk for Alzheimer’s disease in African Americans. Neurology, 54(1), 95–95.
Hamilton, R. H., & Pascual-Leone, A. (1998). Cortical plasticity associated with Braille learning. Trends in Cognitive Sciences, 2(5), 168–174.
Hanushek, E. A., & Kain, J. F., et al. (2002). New evidence about brown v. board of education: The complex effects of school racial composition on achievement. NBER Working Paper.
Harrell, J. P., Hall, S., et al. (2003). Physiological responses to racism and discrimination: An assessment of the evidence. American Journal of Public Health, 93(2), 243–248.
Harris, M. I., Cowie, C. C., et al. (2002). Higher fasting insulin but lower fasting C-peptide levels in African Americans in the US population. Diabetes Metab Res Rev, 18, 149–155.
Haskins, R., & Isaacs, J., et al. (2008). Getting Ahead or Losing Ground: Economic Mobility in America. Economic Mobility Project (pp. 1–120). Washington DC: Brookings Institution.
Hausdorff, J. M., Levy, B. R., et al. (1999). The power of ageism on physical function of older persons: reversibility of age-related gait changes. Journal of American Geriatric Society, 47(11), 1346–1349.
Hauser, R. M., & Warren, J. R. (1997). Socioeconomic indexes for occupations: A review, update, and critique. Sociological Methodology, 27, 177–298.
Hayward, M. D., & Gorman, B. (2004). The long arm of childhood: the influence of early-life social conditions on men’s mortality. Demography, 41(1), 87–107.
Heaton, R. K., & Grant, I., et al. (1986). Differences in neuropsychological test performance associated with age, education, and sex. Neuropsychological assessment of neuropsychiatric disorders (vol. 1, pp. 100–120). New York: Oxford University Press.
Heaton, R. K., & Miller, S. (2004). Revised comprehensive norms for an expanded Halstead–Reitan battery: Demographically adjusted neuropsychological norms for African American and Caucasian Adults. Lutz, FL.
Hébert, R., Lindsay, J., et al. (2000). Vascular dementia: incidence and risk factors in the Canadian study of health and aging. Stroke, 31(7), 1487–1493.
Hess, T. M., Auman, C., et al. (2003). The impact of stereotype threat on age differences in memory performance. Journals of Gerontology Series B-Psychological Sciences and Social Sciences, 58(1), P3–P11.
Himmelstein, D. U. (2005). Illness and Injury as Contributors to Bankruptcy. Cambridge, MA: Harvard Medical School.
Horner, P. J., Power, A. E., et al. (2000). Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. Journal of Neuroscience, 20(6), 2218–2228.
Hoyert, D. L., & S. National Center for Health (2001). Deaths: Final Data for 1999, Dept. of Health and Human Services, Centers for Disease Control and Prevention, National Center for Health Statistics.
Huang, T. L., Carlson, M., Fitzpatrick, A. L., Kuller, L.H., Fried, L. P., Zandi, P. P. (2008). Knee height and arm span: A reflection of early life environment and risk of dementia. Neurology, 70, 1818–1826.
Hummer, R. A., & Benjamins, M. R., et al. (2004). Racial and ethnic disparities in health and mortality among the U.S. elderly population. In N. B. Anderson, R. A. Bulatao, and B. Cohen (Eds.), Critical perspectives on racial and ethnic differences in health in late life (pp. 53–94). National Academies Press.
Ivanovic, D. M., Leiva, B. P., et al. (2000). Long-term effects of severe undernutrition during the first year of life on brain development and learning in Chilean high-school graduates. Nutrition, 16(11–12), 1056–1063.
Jenkins, R., Fox, N. C., et al. (2000). Intracranial volume and Alzheimer disease - Evidence against the cerebral reserve hypothesis. Archives of Neurology, 57(2), 220–224.
Jones, R. N., & Gallo, J. J. (2002). Education and sex differences in the mini-mental state examination effects of differential item functioning. Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 57(6), 548–558.
Kaplan, G. A., Turrell, G., et al. (2001). Childhood socioeconomic position and cognitive function in adulthood. International Journal of Epidemiology, 30(2), 256–263.
Karp, A., Kareholt, I., et al. (2004). Relation of education and occupation-based socioeconomic status to incident Alzheimer’s disease. American Journal of Epidemiology, 159(2), 175.
Katzman, R. (1993). Education and the prevalence of dementia and Alzheimer’s disease. Neurology, 43(1), 13–20.
Katzman, R., Terry, R., et al. (1988). Clinical, pathological, and neurochemical changes in dementia: a subgroup with preserved mental status and numerous neocortical plaques. Annals of Neurology, 23(2), 138–144.
Kaufman, J. S., Cooper, R. S., et al. (1997). Socioeconomic status and health in blacks and whites: the problem of residual confounding and the resilience of race. Epidemiology, 8, 621–628.
Kave, G., Eyal, N., et al. (2008). Multilingualism and cognitive state in the oldest old. Psychology and Aging, 23(1), 70–78.
Kawachi, I., & Berkman, L. F. (2003). Neighborhoods and Health. New York: Oxford University Press, USA.
Kawachi, I., & Subramanian, S. V. (2007). Neighbourhood influences on health. Journal of Epidemiology and Community Health, 61(1), 3–4.
Kempermann, G., & Gage, F. H. (1999a). Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal. Hippocampus, 9(3), 321–332.
Kempermann, G., & Gage, F. H. (1999b). New nerve cells for the adult brain. Scientific American, 280(5), 48–53.
Kempermann, G., Kuhn, H. G., et al. (1998). Experience-induced neurogenesis in the senescent dentate gyrus. Journal of Neuroscience, 18(9), 3206–3212.
Kernie, S. G., Erwin, T. M., et al. (2001). Brain remodeling due to neuronal and astrocytic proliferation after controlled cortical injury in mice. Journal of Neuroscience Research, 66(3), 317–326.
Key, T. J., Verkasalo, P. K., et al. (2001). Epidemiology of breast cancer. The Lancet Oncology, 2(3), 133–140.
Kilander, L., Nyman, H., et al. (1997). Cognitive function, vascular risk factors and education. A cross-sectional study based on a cohort of 70-year-old men. Journal of Internal Medicine, 242(4), 313–321.
Kilander, L., Nyman, H., et al. (1998). Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men. Hypertension, 31(3), 780–786.
King, A. C., Castro, C., et al. (2000). Personal and environmental factors associated with physical inactivity among different racial-ethnic groups of U.S. middle-aged and older-aged women. Health Psychology, 19(4), 354–364.
Kington, R., Carlisle, D., et al. (1998). Racial differences in functional status among elderly US migrants from the South. Social Science & Medicine, 47(6), 831–840.
Kirsch, I. S., Jungeblut, A., et al. (1993). Adult literacy in America: The National Adult Literacy Survey. National Center for Education Statistics, US Department of Education. Washington DC: US Government Printing Office.
Kitayama, N., Vaccarino, V., et al. (2005). Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: A meta-analysis. Journal of Affective Disorders, 88(1), 79–86.
Klineberg, O. (1935). Race differences. New York: Harper & Brothers.
Kramer, A. F., Colcombe, S. J., et al. (2003). Enhancing brain and cognitive function of older adults through fitness training. Journal of Molecular Neuroscience, 20(3), 213–221.
Krieger, N. (1996). Racial discrimination and blood pressure: the CARDIA Study of young black and white adults. American Journal of Public Health, 86(10), 1370–1378.
Krieger, N. (1999). Embodying inequality: A review of concepts, measures, and methods for studying health consequences of discrimination. International Journal of Health Services, 29(2), 295–352.
Krieger, N., Williams, D., et al. (1997). Measuring social class in US public health research: concepts methodologies, guidelines. Annual Review of Public Health, 18, 341–378.
Kroger, E., Andel, R., et al. (2008). Is complexity of work associated with risk of Dementia?: The Canadian Study of Health and Aging. American Journal of Epidemiology, 167(7), 820–830.
Kuh, D., & Ben-Shlomo, Y. (Eds.) (1997). A lifecourse approach to chronic disease epidemiology: tracing the origins of ill-health from early to adult life. Oxford: Oxford University Press.
Lang, I. A., Llewellyn, D. J., et al. (2007). Neighborhood deprivation, individual socioeconomic status, and cognitive function in older people: Analyses from the English Longitudinal Study of Ageing. Journal of the American Geriatrics Society, 56(2), 191–198.
Lara, M., Gamboa, C., et al. (2005). Acculturation and Latino health in the United States: A Review of the Literature and its Sociopolitical Context. Annual Review of Public Health, 26(1), 367–397.
Lauderdale, D. S., Knutson, K. L., et al. (2006). Objectively measured sleep characteristics among early-middle-aged adults—The CARDIA study. American Journal of Epidemiology, 164(1), 5–16.
Lauer, R. M., & Clarke, W. R. (1989). Childhood risk factors for high adult blood pressure: the Muscatine Study. Pediatrics, 84(4), 633–641.
Launer, L. J., Dinkgreve, M. A., et al. (1993). Are age and education independent correlates of the Mini-Mental State Exam performance of community-dwelling elderly? Journal of Gerontology, 48(6), 271–277.
Launer, L. J., Feskens, E. J., et al. (1996). Smoking, drinking, and thinking. The Zutphen Elderly Study. American Journal of Epidemiology, 143(3), 219–227.
Laurin, D., Verreault, R., et al. (2001). Physical activity and risk of cognitive impairment and dementia in elderly persons. Archives of Neurology, 58(3), 498–504.
Lebedev, M. A., Mirabella, G., et al. (2000). Experience-dependent plasticity of rat barrel cortex: redistribution of activity across barrel-columns. Cerebral Cortex, 10(1), 23–31.
Lecours, A. R., Mehler, J., et al. (1987). Illiteracy and brain damage. 1. Aphasia testing in culturally contrasted populations (control subjects). Neuropsychologia, 25, 231–245.
Lee, Y., & Shinkai, S. (2005). Correlates of cognitive impairment and depressive symptoms among older adults in Korea and Japan. International Journal of Geriatric Psychiatry, 20, 576–586.
Lemann, N. (1991). The Promised Land: The Great Black Migration and how it changed America pp. 1–221. New York: AA Knopf.
Leon, D. A. (2001). Commentary: Getting to grips with fetal programming-aspects of a rapidly evolving agenda. International Journal of Epidemiology, 30(1), 96–98.
Levy, B. R. (2003a). Mind matters: Cognitive and physical effects of aging self-stereotypes. Journals of Gerontology Series B-Psychological Sciences and Social Sciences, 58(4), P203–P211.
Levy, B. R. (2003b). Mind matters: Cognitive and physical effects of aging self-stereotypes. Journals of Gerontology Series B: Psychological Sciences and Social Sciences, 58(4), 203–211.
Liebman, J. B., Katz, L. F., et al. (2004). Beyond treatment effects: Estimating the relationship between neighborhood poverty and individual outcomes in the MTO experiment pp. 1–42. Princeton, NJ: Princeton Industrial Relations Section.
Lindesay, J., Briggs, K., et al. (1989). The Guy’s/Age Concern survey. Prevalence rates of cognitive impairment, depression and anxiety in an urban elderly community. British Journal of Psychiatry, 155, 317–329.
Link, B. G., & Phelan, J. (1995). Social conditions as fundamental causes of disease. Journal of Health & Social Behavior Spec, 35, 80–94.
Link, B. G., & Phelan, J. C. (1996) Understanding sociodemographic differences in health—the role of fundamental social causes. American Journal of Public Health, 86(4), 471–472.
Liu, D., Diorio, J., et al. (1997). Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science, 277(5332), 1659–1662.
Liu, D., Diorio, J., et al. (2000). Maternal care, hippocampal synaptogenesis and cognitive development in rats. Nature Neuroscience, 3(8), 799–806.
Liu, H. C., Fuh, J. L., et al. (1998). Prevalence and subtypes of dementia in a rural Chinese population. Alzheimer Disease & Associated Disorders, 12(3), 127–134.
Lleras-Muney, A. (2002). Were compulsory attendance and child labor laws effective? An analysis from 1915 to 1939. Journal of Law & Economics, 45(2), 401–435.
Lleras-Muney, A. (2005). The relationship between education and adult mortality in the US. Review of Economic Studies, 72(1), 189–221.
Loewenstein, D. A., Arguelles, T., et al. (1994). Potential cultural bias in the neuropsychological assessment of the older adult. Journal of Clinical and Experimental Neuropsychology, 16, 623–629.
Logan, J. R. (2001) Ethnic diversity grows, neighborhood integration lags. Albany, NY: Lewis Mumford Center. http://mumford.albany.edu/census/WholePop/WPreport/MumfordReport.pdf (accessed Feb. 11, 2008).
Logan, J. R., & Stowell, J., et al. (2002). Choosing segregation: Racial imbalance in American public schools, 1990–2000, Lewis Mumford Center for Comparative Urban and Regional Research, University at Albany, Business Administration B-10, Albany, NY 12222. Tel: 518-442-4656; Web site: http://www.albany. edu/mumford.
Luo, Y., & Waite, L. J. (2005). The impact of childhood and adult SES on physical, mental, and cognitive well-being in later life. Journals of Gerontology Series B-Psychological Sciences and Social Sciences, 60(2), S93–S101.
Lupien, S. J., de Leon, M., et al. (1998). Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nature Neuroscience, 1(1), 69–73.
Lyketsos, C. G., Chen, L. S., et al. (1999). Cognitive decline in adulthood: an 11.5-year follow-up of the Baltimore Epidemiologic Catchment Area study. American Journal of Psychiatry, 156(1), 58–65.
Lynch, J., & Kaplan, G. (2000). Socioeconomic position. In L. F. Berkman, & I. Kawachi (Eds.), Social Epidemiology (p. 391). New York: Oxford University Press.
Lynn, R. (1998). In support of the nutrition theory. In U. Neisser (Ed.), The rising curve: long-term gains in IQ and related measures (pp. 207–218). Washington DC: American Psychological Association.
Magri, F., Cravello, L., et al. (2006). Stress and dementia: the role of the hypothalamic–pituitary–adrenal axis. Aging Clinical and Experimental Research, 18(2), 167–170.
Maguire, E. A., Gadian, D. G., et al. (2000). Navigation-related structural change in the hippocampi of taxi drivers. Proceedings of the National Academy of Sciences of the United States of America, 97(8), 4398–4403.
Maguire, E. A., Woollett, K., et al. (2006). London taxi drivers and bus drivers: A structural MRI and neuropsychological analysis. Hippocampus, 16(12), 1091–1101.
Manly, J. J., Jacobs, D. M., et al. (1999). Effect of literacy on neuropsychological test performance in nondemented, education-matched elders. Journal of the International Neuropsychological Society, 5(3), 191–202.
Manly, J. J., Jacobs, D. M., et al. (2002). Reading level attenuates differences in neuropsychological test performance between African American and White elders. Journal of the International Neuropsychological Society, 8, 341–348.
Manly, J. J., Touradji, P., et al. (2003). Literacy and memory decline among ethnically diverse elders. Journal of Clinical and Experimental Neuropsychology, 25(5), 680–690.
Marcuse, P. (1997). The enclave, the citadel, and the ghetto: What has changed in the post-Fordist US city. Urban Affairs Review, 33(2), 228.
Margo, R. A. (1985). Disenfranchisement, school finance, and the economics of segregated schools in the United States south, 1980–1910. New York: Garland Publishing.
Margo, R. A. (1990). Race and schooling in the South, 1880–1950: An economic history. Chicago: University of Chicago Press.
Massey, D. S., Condran, G. A., et al. (1987). The effect of residential segregation on black social and economic well-being. Social Forces, 66(1), 29–56.
Massey, D. S., & Denton, N. A. (1988). The dimensions of residential segregation. Social Forces, 67(2), 281–315.
Massey, D. S., & Denton, N. A. (1989). Hypersegregation in US metropolitan areas: Black and Hispanic segregation along five dimensions. Demography, 26(3), 373–391.
Mays, V. M., Cochran, S. D., et al. (2007). Race, race-based discrimination, and health outcomes among African-Americans. Annual Review of Psychology, 58, 201–225.
Mazumder, B. (2005). Fortunate sons: New estimates of intergenerational mobility in the United States using social security earnings data. Review of Economics and Statistics, 87(2), 235–255.
McDowell, I. (2001). Alzheimer’s disease: Insights from epidemiology. Aging Clinical and Experimental Research, 13(3), 143–162.
McEwen, B. S. (2000). Effects of adverse experiences for brain structure and function. Biological Psychiatry, 48(8), 721–731.
McEwen, B. S. (2001). Plasticity of the hippocampus: Adaptation to chronic stress and allostatic load. In B. A. Sorg, & I. R. Bell (Eds.), The role of neural plasticity in chemical intolerance. Annals of the New York Academy of Sciences (vol. 933, pp. 265–277). New York, NY, US: New York Academy of Sciences, New York Academy of Sciences.
McEwen, B. S. (2002). Sex, stress and the hippocampus: allostasis, allostatic load and the aging process. Neurobiology of Aging, 23(5), 921–939.
McMillen, N. R. (1990). Dark Journey: Black Mississippians in the Age of Jim Crow p. 448. Urbana: University of Illinois Press.
McNeilly, M. D., Robinson, E. L., et al. (1995). Effects of racist provocation and social support on cardiovascular reactivity in African American Women. International Journal of Behavioral Medicine, 2(4), 321–338.
Meaney, M. J., Aitken, D. H., et al. (1988). Effect of neonatal handling on age-related impairments associated with the hippocampus. Science, 239(4841, Pt 1), 766–768.
Meaney, M. J., & Bhatnagar, S., et al. (1996). Early environment and the development of individual differences in the hypothalamic–pituitary–adrenal stress response. In C. R. Pfeffer (Ed.), Severe stress and mental disturbance in children (pp. 85–127). Washington, DC, USA, American Psychiatric Press, Inc.
Meaney, M. J., et al. (1985a). Early postnatal handling alters glucocorticoid receptor concentrations in selected brain regions. Behavioral Neuroscience, 99(4), 765–770.
Meaney, M. J., et al. (1985b). The effects of postnatal handling on the development of the glucocorticoid receptor systems and stress recovery in the rat. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 9(5–6), 731–734.
Meaney, M. J., Mitchell, J. B., et al. (1991). The effects of neonatal handling on the development of the adrenocortical response to stress: Implications for neuropathology and cognitive deficits in later life. Psychoneuroendocrinology, 16(1–3), 85–103.
Mechelli, A., Crinion, J. T., et al. (2004). Neurolinguistics: Structural plasticity in the bilingual brain. Nature, 431(7010), 757–757.
Meghir, C., & Palme, M. (2005). Educational reform, ability, and family background. American Economic Review, 95(1), 414–424.
Mensah, G. A., Mokdad, A. H., et al. (2005). State of disparities in cardiovascular health in the United States. Circulation, 111(10), 1233–1241.
Merritt, M. M., Bennett, G. G., et al. (2006). Perceived racism and cardiovascular reactivity and recovery to personally relevant stress. Health Psychology, 25(3), 364–369.
Mirescu, C., Peters, J. D., et al. (2004). Early life experience alters response of adult neurogenesis to stress. Nature Neuroscience, 7(8), 841–846.
Mirowsky, J., & Ross, C. E. (2005). Education, cumulative advantage, and health. Ageing International, 30(1), 27–62.
Moceri, V. M., Kukull, W. A., et al. (2001). Using census data and birth certificates to reconstruct the early-life socioeconomic environment and the relation to the development of Alzheimer’s disease. Epidemiology, 12(4), 383–389.
Morrison, J. A., Biro, F. M., et al. (1992). Obesity and cardiovascular disease—risk-factors in black-and-white girls—the NHLBI growth and health study. American Journal of Public Health, 82(12), 1613–1620.
Mortel, K. F., Meyer, J. S., et al. (1995). Education and occupation as risk factors for dementias of the Alzheimer and ischemic vascular types. Dementia, 6(1), 55–62.
Mossakowski, K. N. (2003). Coping with perceived discrimination: Does ethnic identity protect mental health? Journal of Health and Social Behavior, 44(3), 318–331.
Nakao, K., & Treas, J. (1994). Updating occupational presige and socioeconomic scores: how the new measures measure up. Sociological Methodology, 24, 1–72.
Nelles, G., Jentzen, W., et al. (2001). Arm training induced brain plasticity in stroke studied with serial positron emission tomography. Neuroimage, 13(6 Pt 1), 1146–1154.
Obisesan, T. O., Vargas, C. M., et al. (2000). Geographic variation in stroke risk in the United States - Region, urbanization, and hypertension in the Third National Health and Nutrition Examination Survey. Stroke, 31(1), 19–25.
Ohayon, M. M., & Vecchierini, M. F. (2002). Daytime sleepiness and cognitive impairment in the elderly population. Archives of Internal Medicine, 162(2), 201.
Oreopoulos, P. (2006). Estimating average and local average treatment effects of education when compulsory schooling laws really matter. American Economic Review, 96(1), 152–175.
Paradies, Y. (2006). A systematic review of empirical research on self-reported racism and health. International Journal of Epidemiology, 35(4), 888.
Parker Frisbie, W., Cho, Y., et al. (2001). Immigration and the health of Asian and Pacific islander adults in the United States. American Journal of Epidemiology, 153(4), 372–380.
Peek, M. K., & O’Neill, G. S. (2001). Networks in later life: An examination of race differences in social support networks. International Journal of Aging & Human Development, 52(3), 207–229.
Perlmann, J., & Waldinger, R. (1997). Second generation decline? Children of immigrants, past and present-a reconsideration. International Migration Review, 31, 893–922.
Petersson, K. M., Reis, A., et al. (2001). Cognitive processing in literate and illiterate subjects: a review of some recent behavioral and functional neuroimaging data. Scandinavian Journal of Psychology, 42(3), 251–267.
Plassman, B. L., Welsh, K. A., et al. (1995). Intelligence and education as predictors of cognitive state in late life: a 50-year follow-up. Neurology, 45(8), 1446–1450.
Portes, A. (1995). The Economic Sociology of Immigration: Essays on Networks, Ethnicity and Entrepreneurship. In A. Portes (Ed.), Children of immigrants: Segmented assimilation and its determinants (pp. 248–280). New York: Russell Sage Foundation.
Portes, A., & Zhou, M. I. N. (1993). The new second generation: Segmented assimilation and its variants. The ANNALS of the American Academy of Political and Social Science, 530(1), 74–96.
Power, C., & Hertzman, C. (1997). Social and biological pathways linking early life and adult disease. British Medical Bulletin, 53, 210–222.
Prencipe, M., Casini, A. R., et al. (1996). Prevalence of dementia in an elderly rural population: effects of age, sex, and education. Journal of Neurology, Neurosurgery & Psychiatry, 60(6), 628–633.
Prince, M., Cullen, M., et al. (1994). Risk-factors for Alzheimers-disease and dementia—a case-control study based on the Mrc Elderly Hypertension Trial. Neurology, 44(1), 97–104.
Qiu, C., Backman, L., et al. (2001). The influence of education on clinically diagnosed dementia incidence and mortality data from the Kungsholmen Project. Archives of Neurology, 58(12), 2034–2039.
Raiha, I., Kaprio, J., et al. (1998). Environmental differences in twin pairs discordant for Alzheimer’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 65(5), 785–787.
Ratcliff, G., Ganguli, M., et al. (1998). Effects of literacy and education on measures of word fluency. Brain & Language, 61, 115–122.
Ravelli, A. C., van der Meulen, J. H., et al. (2000). Infant feeding and adult glucose tolerance, lipid profile, blood pressure, and obesity. Archives of Disease in Childhood, 82(3), 248–252.
Read, J. G., & Emerson, M. O. (2005). Racial context, Black immigration and the U. S. Black/White health disparity. Social Forces, 84(1), 181–199.
Redline, S., Kirchner, H. L., et al. (2004). The effects of age, sex, ethnicity, and sleep-disordered breathing on sleep architecture. Archives of Internal Medicine, 164, 406–418.
Reed, D., & Yano, K. (1997). Racial and Ethnic Differences in the Health of Older Americans. In L. Martin, & B. Soldo (Eds.), Cardiovascular disease among elderly Asian Americans (pp. 270–284). Washington, DC: National Academy Press.
Reitz, J. G., & Sklar, S. M. (1997). Culture, race, and the economic assimilation of immigrants. Sociological Forum, 12, 233–277.
Riach, P. A., & Rich, J. (2002). Field experiments of discrimination in the market place. The Economic Journal, 112(483), 480–518.
Richards, M., Brayne, C., et al. (2000). Cognitive function in UK community-dwellings African-Caribbean and white elders: a pilot study. International Journal of Geriatric Psychiatry, 16, 518–527.
Richards, M., Hardy, R., et al. (2001). Birth weight and cognitive function in the British 1946 birth cohort: longitudinal population based study. BMJ, 322(7280), 199–203.
Richards, M., Hardy, R., et al. (2003). Does active leisure protect cognition? Evidence from a national birth cohort. Social Science & Medicine, 56(4), 785–792.
Richman, L. S., Bennett, G. G., et al. (2007). Discrimination, dispositions, and cardiovascular responses to stress. Health Psychology, 26(6), 675–683.
Rocca, W. A. (1990). Prevalence of clinically diagnosed Alzheimer’s disease and other dementing disorders: a door-to-door survey in Appignano, Macerata Province, Italy. Neurology, 40(4), 626–631.
Rosenzweig, M. R., & Bennett, E. L. (1996). Psychobiology of plasticity: effects of training and experience on brain and behavior. Behavioural Brain Research, 78(1), 57–65.
Ross, C. E. (2000). Walking, exercising, and smoking: does neighborhood matter? Social Science & Medicine, 51(2), 265–274.
Ross, C. E., & Mirowsky, J. (1999). Refining the association between education and health: The effects of quantity, credential, and selectivity. Demography, 36(4), 445–460.
Rosselli, M. (1993). Neuropsychology of illiteracy. Special issue: The origins of cognitive activity. Behavioural Neurology, 6, 107–112.
Rosselli, M., Ardila, A., et al. (1990). Neuropsychological assessment in illiterates. II. Language and praxic abilities. Brain and Cognition, 12, 281–296.
Ruggles, S., Sobek, M., Alexander, T., et al. (2004). Intergrated Public Use Microdata Series: Version 3.0 [Machine-readable database]. Minneapolis, MN: Minnesota Population Center.
Ryan, E. L., Baird, R., et al. (2005). Neuropsychological impairment in racial/ethnic minorities with HIV infection and low literacy levels: effects of education and reading level in participant characterization. Journal of the International Neuropsychological Society, 11(7), 889–898.
Sampson, R., & Sharkey, P., et al. (2007). Durable effects of concentrated disadvantage on verbal ability among African-American children. Proceedings of the National Academy of Sciences.
Sapolsky, R. M., Uno, H., et al. (1990). Hippocampal damage associated with prolonged glucocorticoid exposure in primates. Journal of Neuroscience, 10(9), 2897–2902.
Scarmeas, N., Levy, G., et al. (2001). Influence of leisure activity on the incidence of Alzheimer’s Disease. Neurology, 57(12), 2236–2242.
Schaie, K. W. (1989). The hazards of cognitive aging. Gerontologist, 29(4), 484–493.
Schmand, B., Smit, J. H., et al. (1997). The effects of intelligence and education on the development of dementia. A test of the brain reserve hypothesis. Psychological Medicine, 27(6), 1337–1344.
Schneider, D., Greenberg, M. R., et al. (1997). Region of birth and mortality from circulatory diseases among black Americans. American Journal of Public Health, 87(5), 800–804.
Schofield, P. W., Logroscino, G., et al. (1997). An association between head circumference and Alzheimer’s disease in a population-based study of aging and dementia. Neurology, 49(1), 30–37.
Schofield, P. W., Mosesson, R. E., et al. (1995). The age at onset of Alzheimer’s disease and an intracranial area measurement. A relationship. Archives of Neurology, 52(1), 95–98.
Schooler, C. (1998). Environmental complexity and the Flynn effect. In U. Neisser (Ed.), The rising curve: long-term gains in IQ and related measures (pp. 67–79). Washington DC: American Psychological Association.
Schooler, C., & Mulatu, M. S. (2001). The reciprocal effects of leisure time activities and intellectual functioning in older people: A longitudinal analysis. Psychology and Aging, 16(3), 466–482.
Schulman, K., Berlin, J., et al. (1999). The effect of race and sex on physicians’ recommendations for cardiac catheterization. The New England Journal of Medicine, 340(8), 618–626.
Seeman, T. E., Lusignolo, T. M., et al. (2001). Social relationships, social support, and patterns of cognitive aging in healthy, high-functioning older adults: MacArthur studies of successful aging. Health Psychology, 20(4), 243–255.
Sellers, A. H., & Burns, W. J., et al. (2002). Differences in Young Children's IQs on the Wechsler Preschool and Primary Scale of Intelligence-Revised as a Function of Stratification Variables, Lawrence Earlbaum. 9: 65–73.
Sellers, R. M., Caldwell, C. H., et al. (2003). Racial identity, racial discrimination, perceived stress, and psychological distress among African American young adults. Journal of Health and Social Behavior, 44(3), 302–317.
Sharkey, P. (2008). The intergenerational transmission of context. American Journal of Sociology, 113(4), 931–969.
Shumaker, S. A., Legault, C., et al. (2003). Estrogen plus progestin and the incidence of dementia and mild cognitive impairment in postmenopausal women. The Women’s Health Initiative Memory Study: A Randomized Controlled Trial. American Medical Association, 289, 2651–2662.
Siegel, P., & Martin, E., et al. (2001). Language Use and Linguistic Isolation: Historical Data and Methodological Issues. Statistical Policy Working Paper 32: 2000 Seminar on Integrating Federal Statistical Information and Processes. Washington DC: 167–190.
Silverstein, M., & Waite, L. J. (1993). Are blacks more likely than whites to received and provide social support in middle and old-age—yes, no, and maybe so. Journals of Gerontology, 48(4), S212–S222.
Simon, M., Czeh, B., et al. (2005). Age-dependent susceptibility of adult hippocampal cell proliferation to chronic psychosocial stress. Brain Research, 1049(2), 244–248.
Singh, G. K., & Siahpush, M. (2002). Ethnic–immigrant differentials in health behaviors, morbidity, and cause-specific mortality in the United States: An analysis of two national data bases. Human Biology, 74(1), 83–109.
Small, M. L. (2007). Racial differences in networks: Do neighborhood conditions matter? Social Science Quarterly, 88(2), 320–343.
Smedley, B. D., & Stith, A. Y., et al. (2003). Unequal treatment: Confronting racial and ethnic disparities in health care. National Academy Press.
Smith, J. P. (1984). Race and human capital. American Economic Review, 4, 685–698.
Smith, J. P., & Welch, F. (1977). Black-White male wage ratios: 1960–1970. American Economic Review, 67, 323–328.
Smyth, K. A., Fritsch, T., et al. (2004). Worker functions and traits associated with occupations and the development of AD. Neurology, 63(3), 498–503.
Snowdon, D. A., Greiner, L. H., et al. (1997). Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. JAMA, 277(10), 813–817.
Snowdon, D. A., Greiner, L. H., et al. (2000). Linguistic ability in early life and the neuropathology of Alzheimer’s disease and cerebrovascular disease. Findings from the Nun Study. Annals of the New York Academy of Sciences, 903, 34–38.
Snowdon, D. A., Kemper, S. J., et al. (1996). Linguistic ability in early life and cognitive function and Alzheimer’s disease in late life. Findings from the Nun Study. Jama, 275(7), 528–532.
Snowdon, D. A., Ostwald, S. K., et al. (1989). Education, survival, and independence in elderly Catholic sisters, 1936–1988. American Journal of Epidemiology, 130(5), 999–1012.
Spencer, S. J., Steele, C. M., et al. (1999). Stereotype threat and women’s math performance. Journal of Experimental Social Psychology, 35(1), 4–28.
Steele, C. M., & Aronson, J. (1995). Stereotype threat and the intellectual test performance of African Americans. J Pers Soc Psychol, 69(5), 797–811.
Stern, Y. (2002). What is cognitive reserve? Theory and research application of the reserve concept. Journal of the International Neuropsychological Society, 8(03), 448–460.
Stern, Y. (2006). Cognitive reserve and Alzheimer disease. Alzheimer Disease & Associated Disorders, 20(2), 112–117.
Stern, Y., Albert, S., et al. (1999). Rate of memory decline in AD is related to education and occupation: cognitive reserve? Neurology, 53(9), 1942–1947.
Stern, Y., Alexander, G. E., et al. (1992). Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer’s disease. Annals of Neurology, 32(3), 371–375.
Stern, Y., Gurland, B., et al. (1994). Influence of education and occupation on the incidence of Alzheimer’s disease. Jama, 271(13), 1004–1010.
Stewart, R., Johnson, J., et al. (2002). The distribution of Mini-Mental State Examination scores in an older African-Caribbean population compared to MRC CFA Study norms. International Journal of Geriatric Psychiatry, 17, 745–751.
Stewart, R., Richards, M., et al. (2001). Vascular risk and cognitive impairment in an older, British, African-Caribbean population. Journal of the American Geriatrics Society, 49(3), 263–269.
Stimpson, J. P., Ju, H., et al. (2007). Neighborhood deprivation and health risk behaviors in NHANES III. American Journal of Health Behavior, 31(2), 215–222.
Subramanian, S. V., & Glymour, M. M., et al. (2007). Identifying causal ecologic effects on health: a methodological assessment. Macrosocial determinants of health. S. Galea, Springer Media.
Sundquist, J., Winkleby, M. A., et al. (2001). Cardiovascular disease risk factors among older black, Mexican-American, and white women and men: an analysis of NHANES III, 1988–1994. JAGS, 49, 109–116.
Tang, M. X., Cross, P., et al. (2001). Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan. Neurology, 56(1), 49–56.
Taylor, R. J., Chatters, L. M., et al. (1996). Black and white differences in religious participation: a multisample comparison. Journal for the Scientific Study of Religion, 35(4), 403–410.
Teresi, J. A., Kleinman, M., et al. (2000). Modern psychometric methods for detection of differential item functioning: application to cognitive assessment measures. Statistics in Medicine, 19(11–12), 1651–1683.
Theorell, T. (2000). Working conditions and health. In L. F. Berkman, & I. Kawachi (Eds.), Social Epidemiology (pp. 95–117). New York: Oxford University Press.
Thulborn, K. R., Carpenter, P. A., et al. (1999). Plasticity of language-related brain function during recovery from stroke. Stroke, 30(4), 749–754.
Tolnay, S. E. (1998). Educational selection in the migration of southern blacks, 1880–1990. Social Forces, 77(2), 487–514.
Tolnay, S. E. (2003). The African American “Great Migration” and beyond. Annual Review of Sociology, 29, 209–232.
Tsolaki, M., Fountoulakis, K., et al. (2005). Risk factors for clinically diagnosed Alzheimer’s disease: A case-control study of a Greek Population. International Psychogeriatrics, 9(03), 327–341.
Turner, S., & Bound, J. (2003). Closing the gap or widening the divide: The effects’ of the GI Bill and World War II on the educational outcomes of black Americans. Journal of Economic History, 63(1), 145–177.
U.S. Department of Health and Human Services (2004). The Health Consequences of Smoking: A Report of the Surgeon General, Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health.
Valentino, N. A., & Sears, D. O. (2005). Old times there are not forgotten: Race and partisan realignment in the contemporary South. American Journal of Political Science, 49(3), 672–688.
van Praag, H., Kempermann, G., et al. (2000). Neural consequences of environmental enrichment. Nature Reviews Neuroscience, 1(3), 191–198.
Wadsworth, M. (1997). Health inequalities in the life course perspective. Social Science and Medicine, 44(6), 859–869.
Waters, M. C. (2000). Black Identities: West Indian Immigrant Dreams and American Realities, Harvard University Press.
Weaver, I. C. G., Cervoni, N., et al. (2004). Epigenetic programming by maternal behavior. Nature Neuroscience, 7(8), 847–854.
Wechsler, D. (1997). Wechsler Adult Intelligence Scale—III. San Antonio, TX: Psychological Corporation.
Weiss, B. D., Reed, R., et al. (1995). Literacy and performance on the Mini-Mental State Examination. Journal of the American Geriatric Society, 43, 807–810.
Weisskopf, M. G., Wright, R. O., et al. (2004). Cumulative lead exposure and prospective change in cognition among elderly men: The VA Normative Aging Study. American Journal of Epidemiology, 160(12), 1184–1193.
Welch, F. (1966). Measurement of the quality of education. American Economic Review, 56, 379–392.
Welch, F. (1973). Black–White differences in returns to schooling. American Economic Review, 63(5), 893–907.
Weuve, J., Kang, J. H., et al. (2004). Physical activity, including walking, and cognitive function in older women. Jama—Journal of the American Medical Association, 292(12), 1454–1461.
Whalley, L. J., Dick, F. D., et al. (2006). A life-course approach to the aetiology of late-onset dementias. Lancet Neurology, 5(1), 87–96.
Whalley, L. J., Starr, J. M., et al. (2000). Childhood mental ability and dementia. Neurology, 55(10), 1455–1459.
Wheeler, L. R. (1970). Cross-cultural studies of behavior. In I. Al-Issa, & W. Dennis (Eds.), A trans-decade comparison of the IQ’s of Tennessee mountain children (pp. 120–133). New York: Holt, Rinehart & Winston.
White, L., Petrovitch, H., et al. (1996). Prevalence of dementia in older Japanese-American men in Hawaii: The Honolulu-Asia Aging Study. Jama, 276(12), 955–960.
Whitfield, K. E., & Baker-Thomas, T. (1999). Individual differences in aging minorities. International Journal of Aging and Human Development, 48, 73–79.
Whitfield, K. E., Fillenbaum, G. G., et al. (2000). The effect of race and health-related factors on naming and memory. The MacArthur Studies of Successful Aging. Journal of Aging & Health, 12(1), 69–89.
Whitfield, K. E., & Wiggins, S. A. (2003). The impact of desegregation on cognition among older African Americans. Journal of Black Psychology, 29, 275–291.
Wight, R. G., Aneshensel, C. S., et al. (2006). Urban neighborhood context, educational attainment, and cognitive function among older adults. American Journal of Epidemiology, 163(12), 1071–1078.
Williams, D. R., & Jackson, P. B. (2005). Social sources of racial disparities in health. Health Affairs, 24(2), 325.
Williams, D. R., Takeuchi, D. T., et al. (1992). Socioeconomic status and psychiatric disorder among Blacks and Whites. Social Forces, 71(1), 179–194.
Williams, D. R., & Williams-Morris, R. (2000). Racism and mental health: The African American experience. Ethnicity & Health, 5(3), 243–268.
Williams, R., Nesiba, R., et al. (2005). The changing face of inequality in home mortgage lending. Social Problems, 52(2), 181–208.
Williams, W. (1998). Are we raising smarter children today? School and home influences on IQ. The rising curve: long-term gains in IQ and related measures. U. Neisser. Washington DC, American Psychological Association: 125–154.
Willis, S. L., Tennstedt, S. L., et al. (2006). Long-term effects of cognitive training on everyday functional outcomes in older adults. Jama—Journal of the American Medical Association, 296(23), 2805–2814.
Wilson, R. S., Krueger, K. R., et al. (2007). Loneliness and risk of Alzheimer disease. Archives of General Psychiatry, 64(2), 234–240.
Wilson, R. S., Li, Y., et al. (2004). Education and the course of cognitive decline in Alzheimer disease. Neurology, 63(7), 1198–1202.
Wolinsky, F. D., Unverzagt, F. W., et al. (2006). The ACTIVE cognitive training trial and health-related quality of life: Protection that lasts for 5 years. Journals of Gerontology Series a-Biological Sciences and Medical Sciences, 61(12), 1324–1329.
Young, D., Lawlor, P. A., et al. (1999). Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nature Medicine, 5(4), 448–453.
Zavodny, M. (2003). Race, wages, and assimilation among Cuban immigrants. Population Research and Policy Review, 22, 201–219.
Acknowledgments
Maria Glymour was a Robert Wood Johnson Health and Society Scholar at Columbia University when this was written. The authors gratefully acknowledge funding from a Robert Wood Johnson Health and Society Program seed grant and the National Institute on Aging R01 AG016206.
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Glymour, M.M., Manly, J.J. Lifecourse Social Conditions and Racial and Ethnic Patterns of Cognitive Aging. Neuropsychol Rev 18, 223–254 (2008). https://doi.org/10.1007/s11065-008-9064-z
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DOI: https://doi.org/10.1007/s11065-008-9064-z