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Combination of the Claisen-Schmidt reaction, the Michael addition, and the Hantzsch reaction in the synthesis of 2,6′-bis-aryl-3,4′-bipyridines

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Abstract

Pyridine-3-carbaldehyde reacted with 1-(aryl)ethan-1-ones to give 1,5-diaryl-3-(pyridin-3-yl)pentane-1,5-diones, which were further converted to 2′,6′-bis-aryl-3,4′-bipyridines.

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Authors and Affiliations

  1. A. E. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”, 8 ul. Arbuzova, 420088, Kazan, Russian Federation

    V. A. Mamedov, L. V. Mustakimova, O. A. Gerasimov & A. T. Gubaidullin

Authors
  1. V. A. Mamedov
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  2. L. V. Mustakimova
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  3. O. A. Gerasimov
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  4. A. T. Gubaidullin
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Corresponding author

Correspondence to V. A. Mamedov.

Additional information

The authors are grateful for the staf of the Assigned Spectral and Analytical Center for Study of the Structure, Properties and Composition of Substances and Materials of the Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences” for the physicochemical studies.

This work was financially supported in part by the Russian Science Foundation (Project No. 18-13-00315).

Based on the materials of the International Markovnikov Congress on Organic Chemistry (June 21-28, 2019, Moscow-Kazan, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 0517—0524, March, 2020.

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Mamedov, V.A., Mustakimova, L.V., Gerasimov, O.A. et al. Combination of the Claisen-Schmidt reaction, the Michael addition, and the Hantzsch reaction in the synthesis of 2,6′-bis-aryl-3,4′-bipyridines. Russ Chem Bull 69, 517–524 (2020). https://doi.org/10.1007/s11172-020-2792-9

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  • DOI: https://doi.org/10.1007/s11172-020-2792-9

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