Skip to main content

Advertisement

SpringerLink
Log in

Usefulness of dual-energy computed tomography for oral cancer image

  • Original Article
  • Published:
Oral Radiology Aims and scope Submit manuscript

Abstract

Objectives

We aimed to compare dual-energy computed tomography (DECT) virtual monochromatic imaging (VMI) and iodine density imaging (IDI) of oral cancers in terms of visual scoring and tumour volume estimation.

Materials and methods

Nine patients diagnosed with oral cancer who underwent DECT VMI and IDI were enrolled. One radiation oncologist, one head and neck surgeon and nine oral surgeons evaluated image clarity and quality in each patient in terms of metal artefacts due to dental prosthesis, internal tumour structure, tumour–organ boundary and total quality of images for diagnosis. Tumour volume was estimated using VMI, IDI and magnetic resonance imaging (MRI).

Results

The mean score for image artefact was significantly higher for IDI than for VMI in three observers, the mean score for internal structure was significantly higher for IDI than for VMI in five, the mean score for tumour–organ boundary was significantly higher for IDI than for VMI in two and the mean score for total quality of images for diagnosis was significantly higher for IDI than for VMI in five. Standard deviation of estimated tumour volume was not significantly different between VMI and IDI, but that of MRI was significantly lowest in three images.

Conclusions

In DECT for oral cancer, IDI has a visual image superior to VMI; thus, we recommend the use of IDI.

Trial registration

Clinical trial number: UMIN000038994.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

Abbreviations

CT:

Computed tomography

DECT:

Dual-energy computed tomography

IDI:

Iodine density imaging

MRI:

Magnetic resonance imaging

OAR:

Organ at risk

VMI:

Virtual monochromatic imaging

References

  1. Shah JP, Gil Z. Current concepts in management of oral cancer—surgery. Oral Oncol. 2009;45:394–401.

    Article  Google Scholar 

  2. Geets X, Daisne JF, Arcangeli S, et al. Inter-observer variability in the delineation of pharyngo-laryngeal tumor, parotid glands and cervical spinal cord: comparison between CT-scan and MRI. Radiother Oncol. 2005;77:25–31.

    Article  Google Scholar 

  3. Bamberg F, Dierks A, Nikolaou K, et al. Metal artifact reduction by dual energy computed tomography using monoenergetic extrapolation. Eur Radiol. 2011;21:1424–9.

    Article  Google Scholar 

  4. Nakayama Y, Awai K, Funama Y, et al. Abdominal CT with low tube voltage: preliminary observations about radiation dose, contrast enhancement, image quality, and noise. Radiology. 2005;237:945–51.

    Article  Google Scholar 

  5. Toepker M, Moritz T, Krauss B, et al. Virtual non-contrast in second-generation, dual-energy computed tomography: reliability of attenuation values. Eur J Radiol. 2012;81:e398-405.

    Article  Google Scholar 

  6. Stiller W, Schwarzwaelder CB, Sommer CM, et al. Dual-energy, standard and low-kVp contrast-enhanced CT-cholangiography: a comparative analysis of image quality and radiation exposure. Eur J Radiol. 2012;81:1405–12.

    Article  Google Scholar 

  7. Yeh BM, Shepherd JA, Wang ZJ, et al. Dual-energy and low-kVp CT in the abdomen. Am J Radiol. 2009;193:47–54.

    Google Scholar 

  8. Graser A, Johnson TR, Chandarana H, et al. Dual energy CT: preliminary observations and potential clinical applications in the abdomen. Eur Radiol. 2009;19:13–23.

    Article  Google Scholar 

  9. Graser A, Johnson TR, Hecht EM, et al. Dual-energy CT in patients suspected of having renal masses: can virtual nonenhanced images replace true nonenhanced images? Radiology. 2009;252:433–40.

    Article  Google Scholar 

  10. Graser A, Becker CR, Staehler M, et al. Single-phase dual-energy CT allows for characterization of renal masses as benign or malignant. Invest Radiol. 2010;45:399–405.

    Article  Google Scholar 

  11. Ascenti G, Krauss B, Mazziotti S, et al. Dual-energy computed tomography (DECT) in renal masses: nonlinear versus linear blending. Acad Radiol. 2012;19:1186–93.

    Article  Google Scholar 

  12. De Cecco CN, Buffa V, Fedeli S, et al. Dual energy CT (DECT) of the liver: conventional versus virtual unenhanced images. Eur Radiol. 2010;20:2870–5.

    Article  Google Scholar 

  13. Robinson E, Babb J, Chandarana H, et al. Dual source dual energy MDCT: comparison of 80 kVp and weighted average 120 kVp data for conspicuity of hypo-vascular liver metastases. Invest Radiol. 2010;45:413–8.

    Article  Google Scholar 

  14. Tawfik AM, Kerl JM, Razek AA, et al. Image quality and radiation dose of dualenergy CT of the head and neck compared with a standard 120 kVp acquisition. AJNR Am J Neuroradiol. 2011;32:1994–9.

    Article  Google Scholar 

  15. Tawfik AM, Kerl JM, Bauer RW, et al. Dual-energy CT of head and neck cancer: average weighting of low- and high-voltage acquisitions to improve lesion delineation and image quality-initial clinical experience. Invest Radiol. 2012;47:306–11.

    Article  Google Scholar 

  16. Gnannt R, Winklehner A, Goetti R, et al. Low Kilovoltage CT of the neck with 70 kVp: comparison with a standard protocol. AJNR Am J Neuroradiol. 2012;33:1014–9.

    Article  Google Scholar 

  17. Toepker M, Czerny C, Ringl H, et al. Can dual-energy CT improve the assessment of tumor margins in oral cancer? Oral Oncol. 2014;50:221–7.

    Article  Google Scholar 

  18. D’Angelo T, Cicero G, Mazziotti S, et al. Dual energy computed tomography virtual monoenergetic imaging: technique and clinical applications. Br J Radiol. 2019;92:20180546.

    Article  Google Scholar 

  19. Schmoee J, Dirrichs T, Fehrenbacher K, et al. Virtual monoenergetic images (VMI+) in dual-source dual-energy CT venography (DSDE-CTV) of the lower extremity prior to coronary artery bypass graft (CABG): a feasibility study. Acad Radiol. 2020;27:1249–1254.

    Article  Google Scholar 

  20. Foti G, Beltramello A, Minerva G, et al. Identification of residual–recurrent cholesteatoma in operated ears: diagnostic accuracy of dual-energy CT and MRI. Radiol Med. 2019;124:478–86.

    Article  Google Scholar 

  21. Lawrence S, Saskia L, Elisabeth V, et al. RECIST 1.1–update and clarification: from the RECIST Committee. Eur J Cancer. 2016;62:132–7.

    Article  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

  1. Department of Radiation Oncology, Asahi University Hospital, 3-23 Hashimoto-cho, Gifu, 500-8523, Japan

    Osamu Tanaka & Takuya Taniguchi

  2. Department of Oral and Maxillofacial Surgery, Asahi University Hospital, 3-23 Hashimoto-cho, Gifu, 500-8523, Japan

    Makoto Matsubara, Yuichi Ehara, Yasunori Muramatsu & Shinichiro Sumitomo

  3. Department of Head and Neck Surgery, Asahi University Hospital, 3-23 Hashimoto-cho, Gifu, 500-8523, Japan

    Yasuhisa Hasegawa

  4. Department of Radiology, Gifu University Hospital, 1-1 Yanagido, Gifu, 501-1194, Japan

    Chiyoko Makita & Masayuki Matsuo

Authors
  1. Osamu Tanaka
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Makoto Matsubara
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yuichi Ehara
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Takuya Taniguchi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Yasunori Muramatsu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Yasuhisa Hasegawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Chiyoko Makita
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Masayuki Matsuo
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Shinichiro Sumitomo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Osamu Tanaka.

Ethics declarations

Conflict of interest

None.

Ethical approval

Institutional ethical approval: yes. UMIN000038994.  

Patient consent

Written informed consent was obtained from all participants.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Tanaka, O., Matsubara, M., Ehara, Y. et al. Usefulness of dual-energy computed tomography for oral cancer image. Oral Radiol 37, 585–590 (2021). https://doi.org/10.1007/s11282-020-00494-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11282-020-00494-3

Keywords

Search

Navigation