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Can low b value diffusion weighted imaging evaluate the character of cerebrospinal fluid dynamics?

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Abstract

Purpose

We aimed to investigate whether low b value diffusion-weighted imaging (DWI) can show the change of cerebrospinal fluid (CSF) dynamics.

Materials and methods

The subjects of this retrospective study consisted of patients with ventricular dilatation (n = 50) and controls (n = 50). The CSF signal intensity on the b = 500 s/mm2 DWI was evaluated by a scoring method in the lateral, 3rd and 4th ventricles, the cerebral sulci and the Sylvian fissure. The signal void findings adjacent to the septum pellucidum were also evaluated.

Results

The CSF signal intensities were significantly less in lateral ventricle and 3rd ventricle of the ventricular dilatation subjects. In controls, the score for the signal void in the Sylvian fissure showed a significant positive correlation with age. However, other areas did not show a significant correlation with age. The appearance of the characteristic signal void adjacent to the septum pellucidum showed a significant correlation with ventricular dilatation.

Conclusion

Our current study suggests that the CSF signal intensity on the b = 500 s/mm2 DWI may show the changes in CSF dynamics and might be useful to evaluate the overlook of CSF dynamics.

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Authors and Affiliations

  1. Department of Radiology, Graduate School of Medicine, Nagoya University, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan

    Toshiaki Taoka, Shinji Naganawa, Hisashi Kawai & Toshiki Nakane

  2. Siemens Japan K.K., 1-11-1 Osaki, Shinagawa-ku, Tokyo, 141-0032, Japan

    Katsutoshi Murata

Authors
  1. Toshiaki Taoka
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  2. Shinji Naganawa
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  3. Hisashi Kawai
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  4. Toshiki Nakane
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  5. Katsutoshi Murata
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Correspondence to Toshiaki Taoka.

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Conflict of interest

One of the authors is an employee of Siemens Japan K.K.

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All applicable institutional and/or national guidelines for care were followed.

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Taoka, T., Naganawa, S., Kawai, H. et al. Can low b value diffusion weighted imaging evaluate the character of cerebrospinal fluid dynamics?. Jpn J Radiol 37, 135–144 (2019). https://doi.org/10.1007/s11604-018-0790-8

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  • DOI: https://doi.org/10.1007/s11604-018-0790-8

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