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Chronic inflammation-related radiological findings of gallbladder adenomyomatosis

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Abstract

Purpose

This study aimed to assess radiological findings of adenomyomatosis advancing to chronic inflammation to differentiate between adenomyomatosis with and without chronic inflammation.

Materials and methods

We retrospectively identified 79 patients with pathologically proven adenomyomatosis without (n = 10) or with chronic inflammation (n = 69), who underwent computed tomography (CT) and magnetic resonance imaging (MRI) followed by surgery. MRI analysis included evaluation of GB wall-thickening type, presence and location of intramural cysts, and presence of stones. CT analysis included GB wall-thickening type only. Multivariate logistic regression analysis was used to identify the image-based findings of adenomyomatosis associated with chronic inflammation.

Results

On univariate analysis, MRI-based GB wall-thickening type and presence of stones, and CT-based GB wall-thickening type were significantly different between adenomyomatosis with and without chronic inflammation. On multivariate analysis, only the absence of stones was identified as a significant predictor of adenomyomatosis without chronic inflammation (odds ratio 5.58; 95% confidence interval 1.20–26.01; p = 0.029). There was no significant difference in other MRI- and CT-based findings between adenomyomatosis with and without chronic inflammation.

Conclusion

In patients with adenomyomatosis, the presence of stones was independently associated with chronic inflammation.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Konyang University Hospital, Konyang University College of Medicine, 158 Gwanjeodong-ro, Seo-gu, Daejeon, 35365, South Korea

    Hyeon Jin Lee, Woo-Suk Chung, Ji Youn Kim & Ji hae An

  2. Department of Pathology, Daejeon Sun Hospital, Daejeon, South Korea

    Shinyoung Park

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  1. Hyeon Jin Lee
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  2. Woo-Suk Chung
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  3. Ji Youn Kim
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Correspondence to Woo-Suk Chung.

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Lee, H., Chung, WS., Kim, J.Y. et al. Chronic inflammation-related radiological findings of gallbladder adenomyomatosis. Jpn J Radiol 38, 463–471 (2020). https://doi.org/10.1007/s11604-020-00931-7

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  • DOI: https://doi.org/10.1007/s11604-020-00931-7

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