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Integrative treatment for low back pain: An exploratory systematic review and meta-analysis of randomized controlled trials

  • Evidence-Based Integrative Medicine
  • Published:
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Abstract

Objective

Low back pain (LBP) is a common musculoskeletal condition often treated using integrative medicine (IM). Most reviews have focused on a single complementary and alternative medicine (CAM) therapy for LBP rather than evaluating wider integrative approaches. This exploratory systematic review aimed to identify randomized controlled trials (RCTs) and provide evidence on the effectiveness, cost effectiveness and adverse effects of integrative treatment for LBP.

Methods

A literature search was conducted in 12 English and Chinese databases. RCTs evaluating an integrative treatment for musculoskeletal related LBP were included. Reporting, methodological quality and relevant clinical characteristics were assessed and appraised. Metaanalyses were performed for outcomes where trials were sufficiently homogenous.

Results

Fifty-six RCTs were identified evaluating integrative treatment for LBP. Although reporting and methodological qualities were poor, meta-analysis showed a favourable effect for integrative treatment over conventional and CAM treatment for back pain and function at 3 months or less follow-up. Two trials investigated costs, reporting £ 5332 per quality adjusted life years with 6 Alexander technique lessons plus exercise at 12 months follow-up; and an increased total costs of $244 when giving an additional up to 15 sessions of CAM package of care at 12 weeks. Sixteen trials mentioned safety; no severe adverse effects were reported.

Conclusion

Integrative treatment that combines CAM with conventional therapies appeared to have beneficial effects on pain and function. However, evidence is limited due to heterogeneity, the relatively small numbers available for subgroup analyses and the low methodological quality of the included trials. Identification of studies of true IM was not possible due to lack of reporting of the intervention details (registration No. CRD42013003916).

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References

  1. Hu X, Lorenc A, Kemper K, Liu J, Adams J, Robinson N. Defining integrative medicine in narrative and systematic reviews: a suggested checklist for reporting. Eur J Integr Med 2015;7:76–84.

    Article  Google Scholar 

  2. Snyderman R, Weil AT. Integrative medicine: bringing medicine back to its roots. Arch Intern Med 2002;162:395–397.

    Article  PubMed  Google Scholar 

  3. Rees L, Weil A. Integrated medicine: imbues orthodox medicine with the values of complementary medicine. BMJ 2001;322:119–120.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  4. Bell IR, Caspi O, Schwartz GE, Grant KL, Gaudet TW, Rychener D, et al. Integrative medicine and systemic outcomes research: issues in the emergence of a new model for primary health care. Arch Intern Med 2002;162:133–140.

    Article  PubMed  Google Scholar 

  5. Li J, Lin HS. Integrative medicine: a characteristic China model for cancer treatment. Chin J Integr Med 2011;17:243–245.

    Article  PubMed  Google Scholar 

  6. Chan K, Hu X, Razmovski-Naumovski V, Robinson N. Challenges and opportunities of integrating traditional Chinese medicine into mainstream medicine: a review of the current situation. Eur J Integr Med 2015;7:67–75.

    Article  Google Scholar 

  7. Rehberg B. Evidence-based integrative pain medicine. Eur J Integr Med 2010;2:109–113.

    Article  Google Scholar 

  8. Wang L, Zhang M, Guo L, Qi J, Luo H, He H, et al. Clinical pathways based on integrative medicine in Chinese hospitals improve treatment outcomes for patients with acute myocardial infarction: a multicentre, nonrandomized historically controlled trial. Evid Based Complement Alternat Med 2012;2012:821641.

  9. Yang H, Yang J, Wen Z, Zha Q, Nie G, Huang X, et al. Effect of combining therapy with traditional Chinese medicine-based psychotherapy and herbal medicines in women with menopausal syndrome: a randomized controlled clinical trial. Evid Based Complement Alternat Med 2012;2012:354145.

  10. Ong JC, Shapiro SL, Manber R. Combining mindfulness meditation with cognitive-behavior therapy for insomnia: a treatment-development study. Behav Ther 2008;39:171–182.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Morgan L. Is chiropractic a CAM therapy or is it a separate profession? J Can Chiropr Assoc 2005;49:133–136.

    PubMed Central  PubMed  Google Scholar 

  12. Andersson GB. Epidemiological features of chronic low-back pain. Lancet 1999;354:581–585.

    Article  CAS  PubMed  Google Scholar 

  13. Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ 2003;81:646–656.

    PubMed Central  PubMed  Google Scholar 

  14. Lee JH, Choi TY, Lee MS, Lee H, Shin BC, Lee H. Acupuncture for acute low back pain: a systematic review. Clin J Pain 2013;29:172–185.

    Article  PubMed  Google Scholar 

  15. Moroz A, Freed B, Tiedemann L, Bang H, Howell M, Park JJ. Blinding measured: a systematic review of randomized controlled trials of acupuncture. Evid Based Complement Alternat Med 2013;2013:708251.

  16. Yuan J, Purepong N, Kerr DP, Park J, Bradbury I, Mc Donough S. Effectiveness of acupuncture for low back pain: a systematic review. Spine (Phila Pa 1976) 2008;33:E887–900.

    Article  Google Scholar 

  17. Cherkin DC, Sherman KJ, Deyo RA, Shekelle PG. A review of the evidence for the effectiveness, safety, and cost of acupuncture, massage therapy, and spinal manipulation for back pain. Ann Intern Med 2003;138:898–906.

    Article  PubMed  Google Scholar 

  18. MacLennan AH, Wilson DH, Taylor AW. Prevalence and cost of alternative medicine in Australia. Lancet 1996;347:569–573.

    Article  CAS  PubMed  Google Scholar 

  19. NICE clinical guideline 88. Low back pain: early management of persistent non-specific low back pain. Available at: http://www.nice.org.uk/nicemedia/live/11887/44345/44345.pdf, 2009.

  20. van Tulder MW, Koes BW, Bouter LM. Conservative treatment of acute and chronic nonspecific low back pain. A systematic review of randomized controlled trials of the most common interventions. Spine (Phila Pa 1976) 1997;22:2128–2156.

    Article  Google Scholar 

  21. van Tulder MW, Cherkin DC, Berman B, Lao L, Koes BW. The effectiveness of acupuncture in the management of acute and chronic low back pain. A systematic review within the framework of the Cochrane Collaboration Back Review Group. Spine (Phila Pa 1976) 1999;24:1113–1123.

    Article  Google Scholar 

  22. Koes BW, Scholten RJ, Mens JM, Bouter LM. Efficacy of epidural steroid injections for low-back pain and sciatica: a systematic review of randomized clinical trials. Pain 1995;63:279–288.

    Article  CAS  PubMed  Google Scholar 

  23. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009;151:264–269, W64.

    Article  PubMed  Google Scholar 

  24. CRD registration. Available at: http://www.crd.york.ac.uk/NIHR_PROSPERO/display_record.asp?ID=CRD42013003916, 2012.

  25. Shepperd S, Lewin S, Straus S, Clarke M, Eccles MP, Fitzpatrick R, et al. Can we systematically review studies that evaluate complex interventions? PLoS Med 2009;6:e1000086.

  26. Hu X, Hughes J, Fisher P, Lorenc A, Purtell R, Park AL, et al. A pragmatic observational feasibility study on integrated treatment for musculoskeletal disorders: design and protocol. Chin J Integr Med. DOI: 10.1007/s11655-013-1557-9

  27. MacPherson H, White A, Cummings M, Jobst K, Rose K, Niemtzow R, et al. Standards for reporting interventions in controlled trials of acupuncture: the STRICTA recommendations. STandards for Reporting Interventions in Controlled Trails of Acupuncture. Acupunct Med 2002;20:22–25.

    Article  PubMed  Google Scholar 

  28. Moher D, Schulz KF, Altman D, CONSORT Group (Consolidated Standards of Reporting Trials). The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA 2001;285:1987–1991.

    Article  CAS  PubMed  Google Scholar 

  29. Furlan AD, Pennick V, Bombardier C, van Tulder M, Editorial Board, Cochrane Back Review Group. 2009 updated method guidelines for systematic reviews in the Cochrane Back Review Group. Spine (Phila Pa 1976) 2009;34:1929–1941.

    Article  Google Scholar 

  30. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002;21:1539–1558.

    Article  PubMed  Google Scholar 

  31. Holden G, ed. Statistical power analysis for the behavioralsciences. 2nd ed. United State of America: Lawrence Erlbaum Associates; 1988:8–14.

  32. Liang B. Clinical observation of acupuncture-therapy in young and middle-aged lumbar disc herniation. Chin Med Modern Dist Educ Chin (Chin) 2010;8:42–44.

    Google Scholar 

  33. Tuo J, Feng T, Lv X. Clinical observation of electro-acupuncture treatment plus traction for lumbar disc herniation. Shanxi J Tradit Chin Med (Chin) 2011;27:33–34.

    Google Scholar 

  34. Wang N. Acupuncture plus traction therapy for lumbar intrevertebral disc protrusion: curative effect observation. J Clin Rehabil Tissue Engineering Res (Chin) 2007;11:4945–4948.

    Google Scholar 

  35. Wang G, Cui L, Lin Y. Clinical effect of treating lumbar disc herniation with acupuncture combined with traction. Chin Rural Health Service Administration (Chin) 2010;30:600–601.

    Google Scholar 

  36. Wen J. Application analysis of acupuncture in lumbar disc herniation. China J Tradit Chin Med Pharm (Chin) 2011;18:88–89.

    Google Scholar 

  37. Zhao J. Eletroacupuncture for Jia Ji points for lumbar disc herniation. J Clin Acupunct Moxibust (Chin) 2008;24:10–11.

    CAS  Google Scholar 

  38. Yuan L, Zhu Y, Zhu Y, Li W, Xu H. Clinical observation and nursing experiences of a community-based rehabilitation programme for lumbar disc herniation. Chin Manipulation Rehabil Med (Chin) 2012;3:104–105.

    Google Scholar 

  39. Zhong M, Wu S. Clinical observation of Qi Ci combined with traction for lumbar disc herniation. J Guangzhou Univ Tradit Chin Med (Chin) 2013;30:37–39.

    Google Scholar 

  40. Li X, Wang J. Application of floating needle combined with injection of medicines into canalis spinalis after lubar intervertebral disc protrusion surgical operation. Med J Nat Defend Forces Southwest China (Chin) 2008;18:844–845.

    Google Scholar 

  41. Qu M, Ding XN, Liu HB, Liu YQ. Clinical observation on acupuncture combined with nerve block for treatment of lumbar disc herniation. Chin Acupunct Moxibust 2010;30:633–636.

    Google Scholar 

  42. Zhao Z, Zhang X. Clinical observation of 64 cases electroacupuncture combined with lateral recess blocks in Lumbar Disc Herniation. Guid J Tradit Chin Med Phar (Chin) 2011;17:54–55.

    Google Scholar 

  43. Mi Y, Tang Y, Zhang L, Wu Y. Treating lumber-back pain of after operation for prolapse of lumber intervertebral disc by warm needle moxibustion combined with Chinese herbs. J Emerg Tradit Chin Med (Chin) 2010;19:412–413,445.

    Google Scholar 

  44. Zaringhalam J, Manaheji H, Rastqar A, Zaringhalam M. Reduction of chronic non-specific low back pain: a randomised controlled clinical trial on acupuncture and baclofen. Chin Med 2010;5:15.

  45. Leibing E, Leonhardt U, Koster G, Goerlitz A, Rosenfeldt JA, Hilgers R, et al. Acupuncture treatment of chronic low-back pain—a randomized, blinded, placebo-controlled trial with 9-month follow-up. Pain 2002;96:189–196.

    Article  PubMed  Google Scholar 

  46. Meng CF, Wang D, Ngeow J, Lao L, Peterson M, Paget S. Acupuncture for chronic low back pain in older patients: a randomized, controlled trial. Rheumatology (Oxford) 2003;42:1508–1517.

    Article  CAS  Google Scholar 

  47. Molsberger AF, Mau J, Pawelec DB, Winkler J. Does acupuncture improve the orthopedic management of chronic low back pain—a randomized, blinded, controlled trial with 3 months follow up. Pain 2002;99:579–587.

    Article  PubMed  Google Scholar 

  48. Tang Z, Xu Y, Yi J, Tang Y, Wang W. Clinical observation of comprehensive rehabilitation training combined with acupuncture on preventing the recurrence in patients with lumbar disc hernia. Chin J Med Guid (Chin) 2012;14:978–979.

    Google Scholar 

  49. He Y. Clinical observation of 50 cases on the treatment of protrusion of lumbar intervertebral disc with massage and sacral canal injection. Hunan Guid J Tradit Chin Med (Chin) 2004;10:37–45.

    Google Scholar 

  50. LI D, Wang J, Gao Q, Hou J. Comparative study on curative effects of Zheng Gu Li Jin treatment combined with extradural injection and single application of them for treatment of lumbar intervertebral disc protrusion. Clin J Med Officer (Chin) 2011;39:852–855.

    Google Scholar 

  51. Sun K, Yang Y, Zhu J, Liu D. Epidural infusion combined with manual therapy for 40 cases lumbar disc herniation. Clin J Auhui Tradit Chin Med (Chin) 2003;15:410–411.

    Google Scholar 

  52. Tong W. Efficacy of traction and massage combined with caudal injection for 34 cases of lumbar disc herniation. Guid J Tradit Chin Med Pharm (Chin) 2010;16:77–79.

    Google Scholar 

  53. Wen Y, Liang X, Chen X, Li Y. Clinical efficacy of caudal injection in combination with strong stimulation Tuina for lumbar disc herniation. Chin J Phys Med Rehabil (Chin) 2012;34:457–459.

    Google Scholar 

  54. Wen Y, He C, Chen X, Zhang D. Curative effects of sacral injection therapy plus massage in treating acute lumbar sprain. Chin General Pract (Chin) 2012;15:917–920.

    Google Scholar 

  55. Gu F. Treatment of 34 cases of prolapsed lumbar intervertebral discs by massage and three-dimensional traction. Shanghai J Tradit Chin Med (Chin) 2007;41:38–39.

    Google Scholar 

  56. Heng D. Comprehensive treatment of methods based clinical effect of lumbar disc herniation. J Practical Tradit Chin Med (Chin) 2011;27(12):56–57.

    Google Scholar 

  57. Zhang P. Clinical observation on Tui Na and rotatory manual reduction in treating lumbar disc herniation. West J Tradit Chin Med (Chin) 2012;25:98–100.

    CAS  Google Scholar 

  58. Zhu J. Evaluation of the efficacy of traction combined with massage on lumbar intervertebral disc herniation. Clin Med J China (Chin) 2005;12:864–865.

    Google Scholar 

  59. Jiang X, Liu H, Sun F, Tian Y. Clinical evaluation of conservative treatment for lumbar disc herniation under clinical pathway. Med Innov China (Chin) 2010;7:90–91.

    Google Scholar 

  60. Zheng G, Zhang G, Zhang Y. Efficacy of manipulative therapy combined dehydration for lumbar disc herniation. Chin J Tradit Med Traumatol Orthopedics (Chin) 2012;20:56–57.

    Google Scholar 

  61. Grunnesjo MI, Bogefeldt JP, Blomberg SI, Strender LE, Svardsudd KF. A randomized controlled trial of the effects of muscle stretching, manual therapy and steroid injections in addition to ‘stay active’ care on health-related quality of life in acute or subacute low back pain. Clin Rehabil 2011;25:999–1010.

    Article  PubMed  Google Scholar 

  62. Hollinghurst S, Sharp D, Ballard K, Barnett J, Beattie A, Evans M, et al. Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain: economic evaluation. BMJ 2008;337:a2656.

  63. Little P, Lewith G, Webley F, Evans M, Beattie A, Middleton K, et al. Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain. BMJ 2008;337:a884.

  64. Hurwitz EL, Morgenstern H, Kominski GF, Yu F, Chiang LM. A randomized trial of chiropractic and medical care for patients with low back pain: eighteen-month follow-up outcomes from the UCLA low back pain study. Spine (Phila Pa 1976) 2006;31:611–21; discussion 622.

    Article  Google Scholar 

  65. Hurwitz EL, Morgenstern H, Harber P, Kominski GF, Belin TR, Yu F, et al. A randomized trial of medical care with and without physical therapy and chiropractic care with and without physical modalities for patients with low back pain: 6-month follow-up outcomes from the UCLA low back pain study. Spine (Phila Pa 1976) 2002;27:2193–2204.

    Article  Google Scholar 

  66. Cai Y, Fang L. Clinical observation of Chinese and Western combined medicine in lumbar disc herniation. China Modern Doctor (Chin) 2011;49(10):33–34.

    Google Scholar 

  67. Chen J, Tang Y. Three-dimension traction combined with Chinese herbal medicine fumigation for 64 cases lumbar disc herniation. Chin Med Modern Dist Educ China (Chin) 2012;10:31–32.

    Google Scholar 

  68. Qi Y. Effect of jintiange capsule combined with traction on lumbar disc herniation. Pract Pharm Clin Remed (Chin) 2012;15:678–679.

    Google Scholar 

  69. Song H. Clinical observation of Chinese herbal medicine combined with traction for 40 cases lumbar disc herniation in cold damp bi syndrome. Guid J Tradit Chin Med Pharm (Chin) 2010;16:48–49.

    Google Scholar 

  70. Zhu G, Zhang S, Huang B. Effectiveness of external application Huoxuesan in combination with computer guided threedimension traction in lumbar disc herniation. Lishizhen Med Mater Med Res (Chin) 2012;23:2823–2825.

    Google Scholar 

  71. Cao G. Clinical observation of integrative treatment for lumbar disc herniation. Jilin J Tradit Chin Med (Chin) 2006;26:30–31.

    Google Scholar 

  72. Li J, Chen W, Gao Q, Chang Y. Clinical observation of caudal injection plus Gongxiewubei cream combined with lumbar relaxation therapy. Chin J Clin Rational Drug Use (Chin) 2011;4:91–92.

    Google Scholar 

  73. Zhen J, Geng J. Clinical evaluation of Shujin Zhitong Decoction with sacral block in the treatment of lumbar intervertebral disc prolapse. Liaoning J Tradit Chin Med (Chin) 2005;32:1–2.

    Google Scholar 

  74. Zhou J. Combined treatment of lumbar intervertebral disc protrusion with epidural block and traction and Honghua Injection. China Med Herald (Chin) 2008;5:10–11.

    Google Scholar 

  75. Ma Z. AQUATIC spine exercises training on functional recovery in patients with chronic low back pain. Chin J Phys Med Rehabil (Chin) 2012;34:21–22

    Google Scholar 

  76. Xing S, Li S, Ding J, Liu J. Efficacy observation of Yaotongning capsule in the treatment of lumbar disc herniation. China Pharm (Chin) 2011;48:4556–4557.

    Google Scholar 

  77. Yang D, Li Y, Chu Z, Wen H. Efficacy of Duhuo Jisheng decoction combined with physiotherapy on chronic lumbar sprain. Guid J Tradit Chin Med Pharm (Chin) 2012;18:55–56.

    Google Scholar 

  78. Yang Y, Zheng G, Song Y, Su G. Clinical study of peridural injection and acupotomy onherniation of lumbar intervertebral disc. Anhui Med J (Chin) 2009;30:915–917.

    Google Scholar 

  79. Xiao J, Jin T, Chen J. Clinical observation of silver needle combined oxycodone and acetaminophen for chronic low back pain. Chin J Integr Tradit West Med (Chin) 2012;32:1430–1431.

    CAS  Google Scholar 

  80. Yang T, Tong M. Clinical observation of the third lumbar transverse process syndrome small knife treatment. Asia-Pacific Tradit Med (Chin) 2012;8:94–95.

    Google Scholar 

  81. Zhang J, Lu X, Feng Z, Wu Z, Huang X. Clinical observation on treatment to transverse process syndrome of the third lumbar vertebral by the akuptomye release combined with blockage of pain point. Guid China Med (Chin) 2012;10:4–5.

    Google Scholar 

  82. Eisenberg DM, Post DE, Davis RB, Connelly MT, Legedza AT, Hrbek AL, et al. Addition of choice of complementary therapies to usual care for acute low back pain: a randomized controlled trial. Spine (Phila Pa 1976) 2007;32:151–158.

    Article  Google Scholar 

  83. Eisenberg DM, Buring JE, Hrbek AL, Davis RB, Connelly MT, Cherkin DC, et al. A model of integrative care for low-back pain. J Altern Complement Med 2012;18:354–362.

    Article  PubMed Central  PubMed  Google Scholar 

  84. Kuang F, Chen L. Treating lumber-back pain of after operation for prolapse of lumber intervertebral disc by warm needle moxibustion combined with Chinese herbs. J Clin Acupunct Moxibust (Chin) 2009;25:39–40.

    Google Scholar 

  85. Qin XY, Li XX, Suteanu S. Comparative study on Chinese medicine and western medicine for treatment of prolapse of lumbar intervertebral disc. Chin Acupunct Moxibust (Chin) 2007;27:365–368.

    Google Scholar 

  86. Sundberg T, Petzold M, Wandell P, Ryden A, Falkenberg T. Exploring integrative medicine for back and neck pain–a pragmatic randomised clinical pilot trial. BMC Complement Altern Med 2009;9:33.

  87. Wang F. Acupuncture combined with Chinese herbal medicine for 50 cases lumbar disc herniation. Shanxi J Tradit Chin Med (Chin) 2011;32:898–899.

    Google Scholar 

  88. Zeng S. The clinical study on Western combined with traditional Chinese medicine in treatment of lumbar disc herniation. Chin J Prim Med Pharm (Chin) 2011;18:1591–1593.

    Google Scholar 

  89. Zheng D. Clinical observation of Zhi Zhen Fa acupuncture plus three-dimensional massage for discogenic low back pain. J New Chin Med (Chin) 2012;44:142–144.

    Google Scholar 

  90. Sarnat RL, Winterstein J, Cambron JA. Clinical utilization and cost outcomes from an integrative medicine independent physician association: an additional 3-year update. J Manipulative Physiol Ther 2007;30:263–269.

    Article  PubMed  Google Scholar 

  91. Pelletier KR, Astin JA. Integration and reimbursement of complementary and alternative medicine by managed care and insurance providers: 2000 update and cohort analysis. Altern Ther Health Med 2002;8:38–9, 42, 44 passim.

    PubMed  Google Scholar 

  92. Winters M. Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology. Altern Med Rev 2006;11:269–277.

    PubMed  Google Scholar 

  93. Cassileth BR, Deng GE, Gomez JE, Johnstone PA, Kumar N, Vickers AJ, et al. Complementary therapies and integrative oncology in lung cancer: ACCP evidence-based clinical practice guidelines (2nd ed). Chest 2007;132:340S-354S.

  94. Park HL, Lee HS, Shin BC, Liu JP, Shang Q, Yamashita H, et al. Traditional medicine in china, Korea, and Japan: a brief introduction and comparison. Evid Based Complement Alternat Med 2012;2012:429103.

  95. NHS Choices. Traction. Available at: http://www.nhs.uk/conditions/Traction/Pages/Introduction.aspx. Accessed July, 2014.

  96. Lee MS, Shin BC, Choi TY, Kim JI. Randomized clinical trials on Eastern-Western integrative medicine for health care in Korean literature: a systematic review. Chin J Integr Med 2011;17:48–51.

    Article  PubMed  Google Scholar 

  97. Park JJ, Shin J, Choi Y, Youn Y, Lee S, Kwon SR, et al. Integrative package for low back pain with leg pain in Korea: a prospective cohort study. Complement Ther Med 2010;18:78–86.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. School of Health and Social Care, London South Bank University, London, UK

    Xiao-yang Hu  (胡晓阳), Esmé Trevelyan, Ava Lorenc & Nicola Robinson

  2. Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100700, China

    Ni-ni Chen  (陈妮妮), Qian-yun Chai  (柴倩云), Guo-yan Yang  (杨国彦) & Jian-ping Liu  (刘建平)

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  1. Xiao-yang Hu  (胡晓阳)
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Hu, Xy., Chen, Nn., Chai, Qy. et al. Integrative treatment for low back pain: An exploratory systematic review and meta-analysis of randomized controlled trials. Chin. J. Integr. Med. (2015). https://doi.org/10.1007/s11655-015-2125-2

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