References
Biederman J, Monuteaux MC, Kendrick E et al (2005) The CBCL as a screen for psychiatric comorbidity in paediatric patients with ADHD. Arch Dis Child 90:1010–1015
Russell V, Allie S, Wiggins T (2000) Increased noradrenergic activity in prefrontal cortex slices of an animal model for attention-deficit hyperactivity disorder—the spontaneously hypertensive rat. Behav Brain Res 117:69–74
Rajesh AS, Bates G, Wright JG (2006) Atomoxetine-induced electrocardiogram changes. Arch Dis Child 91:1023–1024
Wernicke JF, Faries D, Girod D et al (2003) Cardiovascular effects of atomoxetine in children, adolescents and adults. Drug Saf 26:729–740
Loghin C, Haber H, Beasley CM et al. (2012) Effects of atomoxetine on the qt interval in healthy CYP2D6 poor metabolizers. Br J Clin Pharmacol [Epub ahead of print]
Seifi A, Griffith H, Avestimehr S et al (2011) Atomoxetine-induced myocardial infarction. South Med J 104:153–154
Li WY, Strang SE, Brown DR et al (2010) Atomoxetine changes rat’s HR response to stress from tachycardia to bradycardia via alterations in autonomic function. Auton Neurosci 154:48–53
Drew BJ, Ackerman MJ, Funk M et al (2010) Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. J Am Coll Cardiol 55:934–947
Graham J, Banaschewski T, Buitelaar J, European Guidelines Group et al (2011) European guidelines on managing adverse effects of medication for ADHD. Eur Child Adolesc Psychiatry 20:17–37
Hennessy S, Schelleman H, Daniel GW et al (2010) Cardiovascular safety of ADHD medications: rationale for and design of an investigator-initiated observational study. Pharmacoepidemiol Drug Saf 19:934–941
Roden DM (2006) Long QT syndrome: reduced repolarization reserve and the genetic link. J Intern Med 259:59–69
Scherer D, Hassel D, Bloehs R et al (2009) Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents. Br J Pharmacol 156:226–236
Conflict of interests
The authors have no personal affiliations, financial relationship or any commercial interest to disclose relative to this article. The submitted report or any essential part of it is not published or simultaneously submitted to other publications prior to its appearance in this Journal.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Štuhec, M., Švab, V. Atomoxetine-induced life-threatening long QT syndrome. Ir J Med Sci 182, 535–537 (2013). https://doi.org/10.1007/s11845-013-0925-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11845-013-0925-y