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Introductory Overview of the Natural Experiments for Translation in Diabetes 2.0 (NEXT-D2) Network: Examining the Impact of US Health Policies and Practices to Prevent Diabetes and Its Complications

  • Economics and Policy in Diabetes (ES Huang and AA Baig, Section Editors)
  • Published:
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Abstract

Purpose of Review

Diabetes incidence is rising among vulnerable population subgroups including minorities and individuals with limited education. Many diabetes-related programs and public policies are unevaluated while others are analyzed with research designs highly susceptible to bias which can result in flawed conclusions. The Natural Experiments for Translation in Diabetes 2.0 (NEXT-D2) Network includes eight research centers and three funding agencies using rigorous methods to evaluate natural experiments in health policy and program delivery.

Recent Findings

NEXT-D2 research studies use quasi-experimental methods to assess three major areas as they relate to diabetes: health insurance expansion; healthcare financing and payment models; and innovations in care coordination. The studies will report on preventive processes, achievement of diabetes care goals, and incidence of complications. Some studies assess healthcare utilization while others focus on patient-reported outcomes.

Summary

NEXT-D2 examines the effect of public and private policies on diabetes care and prevention at a critical time, given ongoing and rapid shifts in the US health policy landscape.

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Acknowledgments

The authors acknowledge the significant contributions to this study that were provided by collaborating investigators in the NEXT-D2 (Natural Experiments in Translation for Diabetes) Study Two. The authors also acknowledge the participation of our partnering health systems.

Funding

This publication was made possible by Cooperative Agreements jointly funded by the US Centers for Disease Control and Prevention (CDC), the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK), and the Patient-Centered Outcomes Research Institute (PCORI).

Author information

Authors and Affiliations

  1. Division of General Internal Medicine & Health Services Research, David Geffen School of Medicine, UCLA, 10940 Wilshire Blvd., Suite 700, Los Angeles, CA, 90024, USA

    O. Kenrik Duru

  2. David Geffen School of Medicine at UCLA and Fielding School of Public Health, UCLA, Los Angeles, CA, USA

    Carol M. Mangione

  3. School of Public Health – Health Policy and Management, University of California, Berkeley, Berkeley, CA, USA

    Hector P. Rodriguez

  4. Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA

    Dennis Ross-Degnan & J. Frank Wharam

  5. Pritzker School of Law, Institute for Policy Research, and Kellogg School of Management, Northwestern University, Evanston, IL, USA

    Bernard Black

  6. Institute of Public Health & Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Abel Kho

  7. Oregon Health & Science University, Portland, OR, USA

    Nathalie Huguet & Heather Angier

  8. Department of Population Health Science and Policy, Division of General Internal Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Victoria Mayer

  9. The New York Academy of Medicine, New York, NY, USA

    David Siscovick

  10. Department of Medicine, Pediatrics and Public Health Sciences, Pennsylvania State University College of Medicine at Hershey Medical Center, Hershey, PA, USA

    Jennifer L. Kraschnewski

  11. School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA

    Lizheng Shi

  12. Louisiana Public Health Institute, New Orleans, LA, USA

    Elizabeth Nauman

  13. Centers for Disease Control and Prevention, Division of Diabetes Translation, Atlanta, GA, USA

    Edward W. Gregg & Mohammed K. Ali

  14. Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA

    Mohammed K. Ali

  15. Division of Diabetes, Endocrinology, and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Disease, Bethesda, MD, USA

    Pamela Thornton

  16. Health Care Delivery and Disparities Research Program, Patient-Centered Outcomes Research Institute, Washington, DC, USA

    Steven Clauser

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  1. O. Kenrik Duru
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Corresponding author

Correspondence to O. Kenrik Duru.

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Conflict of Interest

Drs. O. Kenrik Duru, Carol M. Mangione, Hector P. Rodriguez, Dennis Ross-Degnan, Frank Wharam, Bernard Black, Abel Kho, Nathalie Huguet, Heather Angier, Victoria Mayer, David Siscovick, Jennifer Kraschnewski, Lizheng Shi, Elizabeth Nauman, Edward W. Gregg, Mohammed K. Ali, Pamela Thornton, and Steve Clauser declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Disclaimer

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. The findings and conclusions in this report are those of the authors and do not necessarily reflect the views of the Patient-Centered Outcomes Research Institute, its Board of Governors, or Methodology Committee.

Additional information

This article is part of the Topical Collection on Economics and Policy in Diabetes

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Duru, O.K., Mangione, C.M., Rodriguez, H.P. et al. Introductory Overview of the Natural Experiments for Translation in Diabetes 2.0 (NEXT-D2) Network: Examining the Impact of US Health Policies and Practices to Prevent Diabetes and Its Complications. Curr Diab Rep 18, 8 (2018). https://doi.org/10.1007/s11892-018-0977-5

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