Skip to main content

Advertisement

Log in

Role of Paced Breathing for Treatment of Hypertension

  • Device-Based Approaches for Hypertension (M Schlaich, Section Editor)
  • Published:
Current Hypertension Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Hypertension remains to be a major contributor to global morbidity and mortality. Despite a plethora of pharmacological options available, an abundance of patients have uncontrolled blood pressure thus creating the need for additional strategies, including non-pharmacologic approaches. In this review, we discuss the antihypertensive effect of slow and deep respiration by increasing baroreflex sensitivity.

Recent Findings

Asking patients to carry out paced breathing sessions unaccompanied by a personal coach or unaided by a device may be unfeasible. Among proposed breathing techniques, RESPeRATE is a US Food and Drug Administration–certified device that assists slow breathing. In this review, we consider the mechanisms through which guided breathing mechanisms may impact on blood pressure control and alternative techniques.

Summary

Guided breathing techniques along with lifestyle therapies may be helpful as a first step for patients with mild hypertension and prehypertension who do not suffer from cardiovascular disease, renal disease, or diabetes. Drug therapy must be considered after a couple of months if non-pharmacological therapy was unsuccessful. Device-guided paced breathing (DGB) may be recommended for those who cannot obtain full control of their hypertension with medical therapy alone or cannot tolerate potential side effects of pharmacologic treatment. Also, patients with well-controlled hypertension who may wish to try to reduce medication burden may be candidates for DGB. Patients with white coat or labile hypertension who are interested in biofeedback techniques could also be considered.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. • Daskalopoulou SS, Rabi DM, Zarnke KB, Dasgupta K, Nerenberg K, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, DW MK, Tremblay G, Mc Lean D, Tobe SW, Ruzicka M, Burns KD, Vallée M, Ramesh Prasad GV, Lebel M, Feldman RD, Selby P, Pipe A, Schiffrin EL, PA MF, Oh P, Hegele RA, Khara M, Wilson TW, Brian Penner S, Burgess E, Herman RJ, Bacon SL, Rabkin SW, Gilbert RE, Campbell TS, Grover S, Honos G, Lindsay P, Hill MD, Coutts SB, Gubitz G, Campbell NR, Moe GW, Howlett JG, Boulanger JM, Prebtani A, Larochelle P, Leiter LA, Jones C, Ogilvie R, Woo V, Kaczorowski J, Trudeau L, Petrella RJ, Hiremath S, Stone JA, Drouin D, Lavoie KL, Hamet P, Fodor G, Grégoire JC, Fournier A, Lewanczuk R, Dresser GK, Sharma M, Reid D, Benoit G, Feber J, Harris KC, Poirier L, Padwal RS. The 2015 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol. 2015;31(5):549–68. doi:10.1016/j.cjca. 2015.02.016.

    Article  PubMed  Google Scholar 

  2. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003;289(19):2560–72.

    Article  CAS  PubMed  Google Scholar 

  3. He FJ, Li J, Mac Gregor GA. Ef fect of longer term modest salt reduction on blood pressure: Cochrane systematic review and meta-analysis of randomized trials. BMJ. 2013;346:f1325.

    Article  PubMed  Google Scholar 

  4. Park YM, Steck SE, Fung TT, Zhang J, Hazlett LJ, Han K, Merchant AT. Mediterranean diet and mortality risk in metabolically healthy obese and metabolically unhealthy obese phenotypes. Int J Obes. 2016;40(10):1541–9.

    Article  CAS  Google Scholar 

  5. • Authors/Task Force Members, Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, Cooney MT, Corrà U, Cosyns B, Deaton C, Graham Hall MS, Hobbs FD, Løchen ML, Löllgen H, Marques-Vidal P, Perk J, Prescott E, Redon J, Richter DJ, Sattar N, Smulders Y, Tiberi M, Bart Vander Worp H, Van Dis I, Verschuren WM. 2016 European guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Atherosclerosis. 2016;252:207–74. doi:10.1016/j.atherosclerosis. 2016.05.037.

    Article  Google Scholar 

  6. Millar PJ, McGowanCL CVA, Araujo CG, Swaine IL. Evidence for the role of isometric exercise training in reducing blood pressure: potential mechanisms and future directions. Sports Med. 2014;44(3):345–56.

    Article  PubMed  Google Scholar 

  7. Achelrod D, Wenzel U, Frey S. Systematic review and meta-analysis of the prevalence of resistant hypertension in treated hypertensive populations. Am J Hypertens. 2015;28(3):355–61.

    Article  PubMed  Google Scholar 

  8. de la Sierra A, Segura J, Banegas JR, Gorostidi M, de la Cruz JJ, Armario P, Oliveras A, Ruilope LM. Clinical features of 8295 patients with resistant hypertension classified on the basis of ambulatory blood pressure monitoring. Hypertension. 2011;57(5):898–902. doi:10.1161/HYPERTENSIONAHA.110.168948.

    Article  PubMed  Google Scholar 

  9. • Oparil S, Schmieder RE. New approaches in the treatment of hypertension. Circ Res. 2015;116(6):1074–95. doi:10.1161/CIRCRESAHA.116.303603. This review discusses new drugs and interventional treatments in resistant hypertension

    Article  CAS  PubMed  Google Scholar 

  10. • NgFL SM, Mahfoud F, Pathak A, Lobo MD. Device-based therapy for hypertension. Curr Hypertens Rep. 2016;18(8):61. doi:10.1007/s11906-016-0670-5. This review studies seven novel invasive devices employed in resistant hypertension treatment

    Article  Google Scholar 

  11. •• Elliott WJ, Izzo JL. Device-guided breathing to lower blood pressure. Case Report and Clinical Overview. 2006;8(3):23. The first meta-analysis of all clinical trials that evaluates the efficacy of Resperate, demonstrating positive therapeutic effect in hypertensive patients

    Google Scholar 

  12. Gavish B. Device-guided breathing in the home setting: technology, performance and clinical outcomes. Biol Psychol. 2010;84(1):150–6.

    Article  PubMed  Google Scholar 

  13. Lehrer PM, Vaschillo E, Vaschillo B, Lu SE, Eckberg DL, Edelberg R, Shih WJ, Lin Y, Kuusela TA, Tahvanainen KU, Hamer RM. Heart rate variability biofeedback increases baroreflex gain and peak expiratory flow. Psychosom Med. 2003;65(5):796–805.

    Article  PubMed  Google Scholar 

  14. Joseph CN, Porta C, Casucci G, Casiraghi N, Maffeis M, Rossi M, et al. Slow breathing improves arterial baroreflex sensitivity and decreases blood pressure in essential hypertension. Hypertension. 2005;46(4):714–8.

    Article  CAS  PubMed  Google Scholar 

  15. Reyes del Paso GA, Cea JI, González-Pinto A, Cabo OM, Caso R, Brazal J, et al. Short-term effects of a brief respiratory training on baroreceptor cardiac reflex function in normotensive and mild hypertensive subjects. Appl Psychophysiol Biofeedback. 2006;31(1):37–49.

    Article  PubMed  Google Scholar 

  16. Schelegle ES, Green JF. An overview of the anatomy and physiology of slowly adapting pulmonary stretch receptors. Respir Physiol. 2001;125(1–2):17–31.

    Article  CAS  PubMed  Google Scholar 

  17. Lin G, Xiang Q, Fu X, Wang S, Wang S, Chen S, Shao L, Zhao Y, Wang T. Heart rate variability biofeedback decreases blood pressure in prehypertensive subjects by improving autonomic function and baroreflex. J Altern Complement Med. 2012;18(2):143–52. doi:10.1089/acm.2010.0607.

    Article  PubMed  Google Scholar 

  18. •• Sharma M, Frishman WH, Gandhi K. RESPeRATE: nonpharmacological treatment of hypertension. Cardiol Rev. 2011;19(2):47–51. doi:10.1097/CRD.0b013e3181fc1ae6. An excellent review that discusses the effects of paced breathing on blood pressure regulation.

    Article  PubMed  Google Scholar 

  19. Meuret AE, Wilhelm FH, Roth WT. Respiratory biofeedback-assisted therapy in panic disorder. J Clin Psychol. 2004 Feb;60(2):197–207.

    Article  PubMed  Google Scholar 

  20. Giardino ND, Chan L, Borson S. Combined heart rate variability and pulse oximetry biofeedback for chronic obstructive pulmonary disease: preliminary findings. Appl Psychophysiol Biofeedback. 2004;29(2):121–33.

    Article  PubMed  Google Scholar 

  21. Harada D, Asanoi H, Takagawa J, Ishise H, Ueno H, Oda Y, Goso Y, Joho S, Inoue H. Slow and deep respiration suppresses steady-state sympathetic nerve activity in patients with chronic heart failure: from modeling to clinical application. Am J Physiol Heart Circ Physiol. 2014;307(8):H1159–68. doi:10.1152/ajpheart.00109.2014.

    Article  CAS  PubMed  Google Scholar 

  22. • RESPERATE to lower blood pressure. http://www.resperate.com/. Accessed 24 Nov 2016. Information about the device from the manufacturer.

  23. • Landman GW, Drion I, van Hateren KJ, van Dijk PR, Logtenberg SJ, Lambert J, et al. Device-guided breathing as treatment for hypertension in type 2 diabetes mellitus: a randomized, double-blind, sham-controlled trial. JAMA Intern Med. 2013;173(14):1346–50. doi:10.1001/jamainternmed.2013.6883. This recent study establishes that RESPERATE does not improve BP in hypertensive diabetic patients

    Article  PubMed  Google Scholar 

  24. Huang AJ, Subak LL. What constitutes an adequate evaluation of device-guided breathing? JAMA Intern Med. 2014;174(4):637. doi:10.1001/jamainternmed.2013.13791.

    Article  PubMed  Google Scholar 

  25. • Howorka K, Pumprla J, Tamm J, Schabmann A, Klomfar S, Kostineak E, et al. Effects of guided breathing on blood pressure and heart rate variability in hypertensive diabetic patients. Auton Neurosci. 2013;179(1–2):131–7. doi:10.1016/j.autneu. 2013.08.065. This recent study demonstrates that RESPERATE improves BP in well controlled hypertensive diabetic patients

    Article  PubMed  Google Scholar 

  26. Wojcicki JM, Geissler JD, Stokes CW, Heyman MB, Tran CT. The use of the RESPeRATE device to lower blood pressure in inner city obese adolescents and children: a pilot feasibility study. High Blood Press Cardiovasc Prev. 2013;20(2):89–92. doi:10.1007/s40292-013-0014-3.

    Article  PubMed  PubMed Central  Google Scholar 

  27. • Harada D, Asanoi H, Takagawa J, Ishise H, Ueno H, Oda Y, Goso Y, Joho S, Inoue H. Slow and deep respiration suppresses steady-state sympathetic nerve activity in patients with chronic heart failure: from modeling to clinical application. Am J Physiol Heart Circ Physiol. 2014;15(307(8)):H1159–68. This recent trial demonstrates that DGB suppresses MSNA in patients with heart failure

    Article  Google Scholar 

  28. de Barros S, da Silva GV, de Gusmão JL, de Araujo TG, Mion D Jr. Reduction of sympathetic nervous activity with device-guided breathing. J Clin Hypertens (Greenwich). 2014;16(8):614–5.

    Article  Google Scholar 

  29. • Drozdz T, Bilo G, Debicka-Dabrowska D, Klocek M, Malfatto G, Kielbasa G, Styczkiewicz K, Bednarek A, Czarnecka D, Parati G, Kawecka-Jaszcz K. Blood pressure changes in patients with chronic heart failure undergoing slow breathing training. Blood Press. 2016;25(1):4–10. This recent trial demonstrates that DGB does not affect the prevalence of OH in heart failure

    Article  PubMed  Google Scholar 

  30. •• Cernes R, Zimlichman R. RESPeRATE: the role of paced breathing in hypertension treatment. J Am Soc Hypertens. 2015;9(1):38–47. doi:10.1016/j.jash. 2014.10.002. This systematic review of all available clinical trials finds a positive effect of paced breathing and recommends this approach in hypertensive patients

    Article  PubMed  Google Scholar 

  31. Grossman E, Grossman A, Schein MH, Zimlichman R, Gavish B. Breathing-control lowers blood pressure. J Hum Hypertens. 2001;15(4):263–9.

    Article  CAS  PubMed  Google Scholar 

  32. Meles E, Giannattasio C, Failla M, Gentile G, Capra A, Mancia G. Nonpharmacologic treatment of hypertension by respiratory exercise in the home setting. Am J Hypertens. 2004;17(4):370–4.

    Article  PubMed  Google Scholar 

  33. Rosenthal T, Alter A, Peleg E, Gavish B. Device-guided breathing exercises reduce blood pressure: ambulatory and home measurements. Am J Hypertens. 2001;14(1):74–6.

    Article  CAS  PubMed  Google Scholar 

  34. Bae JH, Kim JH, Choe KH, Hong SP, Kim KS, Kim CH, et al. Blood pressure change following 8-week, 15-minute daily treatment with paced breathing guided by a device: a Korean multi-center study. J Clin Hypertens. 2006;8(5):86.

    Google Scholar 

  35. Anderson DE, Mc Neely JD, Windham BG. Regular slow-breathing exercise effects on blood pressure and breathing patterns at rest. Hum Hypertens. 2010;24(12):807–13. doi:10.1038/jhh. 2010.18.

    Article  CAS  Google Scholar 

  36. Elliot WJ, Izzo JL, White WB, Rosing DR, Snyder CS, Alter A, et al. Graded blood pressure reduction in hypertensive outpatients associated with use of a device to assist with slow breathing. J Clin Hypertens (Greenwich). 2004;6(10):553–9.

    Article  Google Scholar 

  37. Viskoper R, Shapira I, Priluck R, Mindlin R, Chornia L, Laszt A, et al. Nonpharmacologic treatment of resistant hypertensives by device-guided slow breathing exercises. Am J Hypertens. 2003;16(6):484–7.

    Article  PubMed  Google Scholar 

  38. Schein MH, Gavish B, Herz M, Rosner-Kahana D, Naveh P, Knishkowy B, et al. Treating hypertension with a device that slows and regularizes breathing: a randomized, double-blind controlled study. J Hum Hypertens. 2001;15(4):271–8.

    Article  CAS  PubMed  Google Scholar 

  39. Altena MR, Kleefstra N, Logtenberg SJ, Groenier KH, Houweling ST, Bilo HJ. Effect of device-guided breathing exercises on blood pressure in patients with hypertension: a randomized controlled trial. Blood Press. 2009;18(5):273–9. doi:10.3109/08037050903272925.

    Article  PubMed  Google Scholar 

  40. Logtenberg SJ, Kleefstra N, Houweling ST, Groenier KH, Bilo HJ. Effect of device-guided breathing exercises on blood pressure in hypertensive patients with type 2 diabetes mellitus: a randomized controlled trial. J Hypertens. 2007;25(1):241–6.

    Article  CAS  PubMed  Google Scholar 

  41. Schein MH, Gavish B, Baevsky T, Kaufman M, Levine S, Nessing A, et al. Treating hypertension in type II diabetic patients with device-guided breathing: a randomized controlled trial. J Hum Hypertens. 2009;23(5):325–31.

    Article  CAS  PubMed  Google Scholar 

  42. Oneda B, Ortega KC, Gusmão JL, Araújo TG, Mion D. Sympathetic nerve activity is decreased during device-guided slow breathing. Hypertens Res. 2010;33(7):708–12. doi:10.1038/hr.2010.74.

    Article  PubMed  Google Scholar 

  43. Bertisch SM, Schomer A, Kelly EE, Baloa LA, Hueser LE, Pittman SD, et al. Device-guided paced respiration as an adjunctive therapy for hypertension in obstructive sleep apnea: a pilot feasibility study. Appl Psychophysiol Biofeedback. 2011;36(3):173–9. doi:10.1007/s10484-011-9158-x.

    Article  PubMed  PubMed Central  Google Scholar 

  44. • Landman GW, van Hateren KJ, van Dijk PR, Logtenberg SJ, Houweling ST, Groenier KH, Bilo HJ, Kleefstra N. Efficacy of device-guided breathing for hypertension in blinded, randomized, active-controlled trials: a meta-analysis of individual patient data. JAMA Intern Med. 2014;174(11):1815–21. doi:10.1001/jamainternmed. 2014.4336. A recent meta-analysis that criticizes the DGB trials sponsored by manufacturer and appreciates only three studies. DGB as a routine treatment is not recommended

    Article  PubMed  Google Scholar 

  45. Mahtani KR, Nunan D, Heneghan CJ. Device-guided breathing exercises in the control of human blood pressure: systematic review and meta-analysis. J Hypertens. 2012;30(5):852–60. doi:10.1097/HJH.0b013e3283520077.

    Article  CAS  PubMed  Google Scholar 

  46. • Mahtani KR, Beinortas T, Bauza K, Nunan D. Device-guided breathing for hypertension: a summary evidence review. Curr Hypertens Rep. 2016;18(4):33. doi:10.1007/s11906-016-0631-z. A review that presents recent DGB clinical studies sponsored and not sponsored by the manufacturer and summarizes a recent meta-analysis previously published by some authors of this paper. DGB as a routine treatment is not recommended

    Article  PubMed  Google Scholar 

  47. van Hateren KJ, Landman GW, Logtenberg SJ, Bilo HJ, Kleefstra N. Device-guided breathing exercises for the treatment of hypertension: an overview. World J Cardiol. 2014;6(5):277–82. doi:10.4330/wjc. v6.i5.277.

    PubMed  PubMed Central  Google Scholar 

  48. Bhavanani A.B.,Madanmohan, and Sanjay Z. Immediate effect of chandra nadi pranayama (left unilateral forced nostril breathing) on cardiovascular parameters in hypertensive patients. Int J Yoga 2012; 5(2):108–111. doi: 10.4103/0973-6131. 98221.

  49. Pramanik T, Sharma HO, Mishra S, Mishra A, Prajapati R, Singh S. Immediate effect of slow pace bhastrika pranayama on blood pressure and heart rate. J Altern Complement Med. 2009;15(3):293–5. doi:10.1089/acm. 2008.0440.

    Article  PubMed  Google Scholar 

  50. Wang SZ, Li S, Xu XY, Lin GP, Shao L, Zhao Y, et al. Effect of slow abdominal breathing combined with biofeedback on blood pressure and heart rate variability in prehypertension. J Altern Complement Med. 2010;16(10):1039–45. doi:10.1089/acm. 2009.0577.

    Article  PubMed  Google Scholar 

  51. Nakao M, Nomura S, Shimosawa T, Fujita T, Kuboki T. Blood pressure biofeedback treatment of white-coat hypertension. J Psychosom Res. 2000;48(2):161–9.

    Article  CAS  PubMed  Google Scholar 

  52. Yucha CB, Tsai PS, Calderon KS, Tian L. Biofeedback-assisted relaxation training for essential hypertension: who is most likely to benefit? J Cardiovasc Nurs. 2005;20(3):198–205.

    Article  PubMed  Google Scholar 

  53. Hartley L, Mavrodaris A, Flowers N, Ernst E, Barnes VA RK, Treiber FA, Johnson MH. Impact of transcendental meditation for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2014;12:CD010359.

    Google Scholar 

  54. Uddin AA, Morita PP, Tallevi K, Armour K, Li J, Nolan RP, Cafazzo JA. Development of a wearable cardiac monitoring system for behavioral neurocardiac training: a usability study. J MIR M health Uhealth. 2016;22(4(2)):e45. doi:10.2196/mhealth.5288.

    Article  Google Scholar 

  55. Nolan RP, Floras JS, Harvey PJ, Kamath MV, Picton PE, Chessex C, Hiscock N, Powell J, Catt M, Hendrickx H, Talbot D, Chen MH. Behavioral neurocardiac training in hypertension: a randomized, controlled trial. Hypertension. 2010;55(4):1033–9. doi:10.1161/HYPERTENSIONAHA.109.146233.

    Article  CAS  PubMed  Google Scholar 

  56. Alabdulgader AA. Coherence: a novel nonpharmacological modality for lowering blood pressure in hypertensive patients. Glob Adv Health Med. 2012;1(2):56–64. doi:10.7453/gahmj.2012.1.2.011.

    Article  PubMed  PubMed Central  Google Scholar 

  57. Vaschillo E, Lehrer P, Rishe N, Konstantinov M. Heart rate variability biofeedback as a method for assessing baroreflex function: a preliminary study of resonance in the cardiovascular system. Appl Psychophysiol Biofeedback. 2002;27(1):1–27.

    Article  PubMed  Google Scholar 

  58. •• Lehrer PM, Gevirtz R. Heart rate variability biofeedback: how and why does it work? Front Psychol. 2014;2(5):756. doi:10.3389/fpsyg. 2014.00756. A review that summarizes the possible mechanisms for the effectiveness of respiratory sinus arrhythmia

    Google Scholar 

  59. • Hering D, Kucharska W, Kara T, Somers VK, Parati G, Narkiewicz K. Effects of acute and long-term slow breathing exercise on muscle sympathetic nerve activity in untreated male patients with hypertension. J Hypertens. 2013;31(4):739–46. doi:10.1097/HJH.0b013e32835eb2cf. This recent trial demonstrates that DGB improves MSNA in short term and attenuates cardiovascular response to mental stress

    Article  CAS  PubMed  Google Scholar 

  60. Cramer H, Haller H, Lauche R, Steckhan N, Michalsen A, Dobos G. A systematic review and meta-analysis of yoga for hypertension. Am J Hypertens. 2014;27(9):1146–51. doi:10.1093/ajh/hpu 078.

    Article  PubMed  Google Scholar 

  61. Nidich SI, Rainforth MV, Haaga DA, Hagelin J, Salerno JW, Travis F, et al. A randomized controlled trial on effects of the Transcendental Meditation program on blood pressure, psychological distress, and coping in young adults. AmJ Hypertens. 2009;22(12):1326–31. doi:10.1038/ajh. 2009.184.

    Article  Google Scholar 

  62. Wallen MP, Gomersall SR, Keating SE, Wisløff U, Coombes JS. Accuracy of heart rate watches: implications for weight management. PLoS One. 2016;11(5):e0154420. doi:10.1371/journal.pone.0154420. eCollection 2016

    Article  PubMed  PubMed Central  Google Scholar 

  63. •• Brook RD, Jackson EA, Giorgini P, McGowan CL. When and how to recommend ‘alternative approaches’ in the management of high blood pressure. Am J Med. 2015;128(6):567–70. doi:10.1016/j.amjmed.2014.12.029. A review that presents who are hypertensive candidates for trials of alternative approaches, such as device-guided breathing and isometric handgrip

    Article  PubMed  Google Scholar 

  64. • Sica DA. Device-guided breathing and hypertension: a yet to be determined positioning. Am J Med. 2015;1208(6):567–70. An editorial that recommends device-guided breathing for several types of hypertensive patients

    Google Scholar 

  65. •• Brook RD, Appel LJ, Rubenfire M, Ogedegbe G, Bisognano JD, Elliott WJ, et al. Beyond medications and diet: alternative approaches to lowering blood pressure: a scientific statement from the American Heart Association. Hypertension. 2013;61(6):1360–83. doi:10.1161/HYP.0b013e318293645f. The American Heart Association confers a Class IIA, Level of Evidence B on device-guided breathing.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Reuven Zimlichman.

Ethics declarations

Conflict of Interest

R.Z. served as a medical consultant to Intercure, the manufacturer of RESPeRATE, from March 21, 2013, until July 11, 2014. R.C. declares no conflict of interest relevant to this manuscript.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

This article is part of the Topical Collection on Device-Based Approaches for Hypertension

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cernes, R., Zimlichman, R. Role of Paced Breathing for Treatment of Hypertension. Curr Hypertens Rep 19, 45 (2017). https://doi.org/10.1007/s11906-017-0742-1

Download citation

  • Published:

  • DOI: https://doi.org/10.1007/s11906-017-0742-1

Keywords

Navigation