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Brachytherapy-associated erectile dysfunction

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Abstract

After permanent prostate brachytherapy, erectile dysfunction is more common than initially reported. Using validated patient-administered instruments, approximately half of patients develop erectile dysfunction within 5 years of implantation. Preimplant erectile function and dose to the proximal penis appear to be the strongest predictors of brachytherapy-related impotence. Fortunately, the majority of patients respond to phosphodiesterase-5 inhibitors. Further elucidation of mechanisms of brachytherapyrelated erectile dysfunction may help to refine treatment techniques and improve potency preservation.

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Authors and Affiliations

  1. Schiffler Cancer Center, Wheeling Hospital, 1 Medical Park, 26003-6300, Wheeling, WV, USA

    Gregory S. Merrick MD

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  1. Gregory S. Merrick MD
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  2. Wayne M. Butler PhD
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  3. Kent E. Wallner MD
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Merrick, G.S., Butler, W.M. & Wallner, K.E. Brachytherapy-associated erectile dysfunction. Current Sexual Health Reports 2, 21–26 (2005). https://doi.org/10.1007/s11930-005-0018-7

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