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Cardiogenic Shock Due to Aluminum Phosphide Poisoning Treated with Intra-aortic Balloon Pump: A Report of Two Cases

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Abstract

The mortality rate from aluminum phosphide (AlP) poisoning is as high as 70–100%, with refractory hypotension and severe metabolic acidosis being the two most common presentations in this poisoning. As this poisoning has no specific antidote, treatments revolve around supportive care. Cardiogenic shock created by toxic myocarditis is considered the main cause of mortality in these patients. Meanwhile, the intra-aortic balloon pump (IABP) has been suggested for the treatment of cardiogenic shock. This article reports the successful treatment of cardiogenic shock caused by AlP poisoning in a 17-year-old man and a 21-year-old woman using the IABP procedure.

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Acknowledgements

The authors want to convey an appreciation of Dr. George Sam Wang for his nice comments in editing the manuscript.

Funding

It is the outcome of an in-house financially non-supported study.

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Authors and Affiliations

  1. Rocky Mountain Poison and Drug Center, Denver Health, Denver, CO, USA

    Omid Mehrpour

  2. Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand, 9717853577, Iran

    Sadegh Asadi, Nastaran Mahmoodabadi & SeyedYoosef Javadmoosavi

  3. Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

    Mohammad Ali Yaghoubi

  4. Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran

    Nahid Azdaki

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  1. Omid Mehrpour
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  2. Sadegh Asadi
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  5. Nastaran Mahmoodabadi
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  6. SeyedYoosef Javadmoosavi
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All authors equally contributed in collecting data and writing manuscript and revision. All the authors have read and approved the final manuscript.

Corresponding author

Correspondence to Omid Mehrpour.

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The authors declare that they have no conflict of interest.

Ethical Approval

This study involved human data and was conducted in strict accordance with the Declaration of Helsinki.

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Consent for publication of these two cases was obtained.

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Handling Editor: Y. James Kang.

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Mehrpour, O., Asadi, S., Yaghoubi, M.A. et al. Cardiogenic Shock Due to Aluminum Phosphide Poisoning Treated with Intra-aortic Balloon Pump: A Report of Two Cases. Cardiovasc Toxicol 19, 474–481 (2019). https://doi.org/10.1007/s12012-019-09513-0

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