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Universal Software Architecture of Magnetic Resonance-Guided Focused Ultrasound Surgery System and Experimental Study

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Abstract

Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is an emerging, non-invasive hyperthermia technology which can be used for the treatment of benign and malignant tumours, in conjunction with intracranial neurological diseases. To treat different indications, it is often necessary to design special focused ultrasound devices and treatment plans, which poses great challenges and results in substantial costs during software development. This article introduces a general software architecture that can be applied to three different focused ultrasound devices for the treatment of uterine fibroids, breast fibroids, and pain palliation of bone metastases, respectively, and can be integrated with GE Discovery or Signa MRI scanners and Xingaoyi BroadScan MRI scanners. Finally, the proposed software architecture was shown to possess desirable universality and safety through various tests and animal experimental studies.

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Acknowledgement

We thank Shanghai General Hospital for the support of the animal trials. We thank Dr. ZONG Shenyan and Dr. WU Nan for review and revision of this article.

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Authors and Affiliations

  1. Shanghai Shende Medical Device Technology Co., Ltd., Shanghai, 200233, China

    Shengfa Zhang  (张胜发) & Shan Qiao  (乔杉)

  2. Shanghai General Hospital, Shanghai, 200080, China

    Na Tang  (唐纳) & Han Wang  (王悍)

  3. School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China

    Guofeng Shen  (沈国峰)

Authors
  1. Shengfa Zhang  (张胜发)
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  2. Na Tang  (唐纳)
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  3. Guofeng Shen  (沈国峰)
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  4. Han Wang  (王悍)
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  5. Shan Qiao  (乔杉)
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Corresponding author

Correspondence to Na Tang  (唐纳).

Additional information

Foundation item: the National Natural Science Foundation of China (Nos. 81727806 and 11774231); the National Key Research and Development Program of Ministry of Science and Technology (No. 2017YFC0108900); the Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support—Gainers from Shanghai Jiao Tong University School of Medicine (No. 20152230); the Emerging Frontier Technology Joint Research Program of Shanghai Shen-Kang Hospital Development Center (No. SHDC2017127)

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Zhang, S., Tang, N., Shen, G. et al. Universal Software Architecture of Magnetic Resonance-Guided Focused Ultrasound Surgery System and Experimental Study. J. Shanghai Jiaotong Univ. (Sci.) 26, 471–481 (2021). https://doi.org/10.1007/s12204-021-2325-1

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  • DOI: https://doi.org/10.1007/s12204-021-2325-1

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