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Six-month clinical outcomes of the Tryton Side Branch Stent for the treatment of bifurcation lesions

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Abstract

Aims

Percutaneous coronary intervention (PCI) of a bifurcation lesion (BL) is still associated with poorer clinical outcomes when compared with PCI of a non-BL. Therefore, several dedicated coronary bifurcation stents, such as the Tryton Side Branch Stent™ (Tryton Medical, Durham, NC, USA), were developed to improve clinical outcomes. We investigated 6-month clinical outcomes after placement of a Tryton stent in 91 patients treated for 93 BLs in our centre.

Methods and results

All consecutive patients who have undergone PCI of a BL treated with the Tryton stent in our centre were included. Outcomes were defined as any death, cardiac death, myocardial infarction (MI), any revascularisation, ischaemia-driven target vessel revascularisation (TVR), ischaemia-driven target lesion revascularisation (TLR), stent thrombosis, and target vessel failure (TVF; composite of cardiac death, MI, and ischaemia-driven TVR). Event rates were estimated using the Kaplan-Meier method. Thirty-eight (42 %) patients with acute coronary syndrome (ACS) were included (16 % ST-segment elevation MI (STEMI)). The 6-month event rates were 5.4 % (death), 4.3 % (cardiac death), 2.2 % (MI), 4.5 % (any revascularisation), 4.5 % (TVR), 4.5 % (TLR) and 9.7 % (TVF).

Conclusion

In a real-world all-comers single-centre registry, the use of the Tryton Side Branch Stent was associated with acceptable procedural and promising clinical outcomes at 6 months, including ACS and STEMI patients.

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Authors and Affiliations

  1. Department of Cardiology, Academic Medical Center – University of Amsterdam, Meibergdreef 9, Room B2-125, 1105 AZ, Amsterdam, the Netherlands

    M. J. Grundeken, M. Smits, R. E. Harskamp, P. Damman, P. Woudstra, A. J. Hoorweg, J. Baan Jr, E. K. Arkenbout, J. J. Piek, M. M. Vis, J. P. S. Henriques, K. T. Koch, J. G. Tijssen, R. J. de Winter & J. J. Wykrzykowska

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  1. M. J. Grundeken
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  2. M. Smits
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  3. R. E. Harskamp
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  4. P. Damman
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  5. P. Woudstra
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  8. E. K. Arkenbout
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  9. J. J. Piek
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  11. J. P. S. Henriques
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  12. K. T. Koch
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  13. J. G. Tijssen
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  15. J. J. Wykrzykowska
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Correspondence to J. J. Wykrzykowska.

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Grundeken, M.J., Smits, M., Harskamp, R.E. et al. Six-month clinical outcomes of the Tryton Side Branch Stent for the treatment of bifurcation lesions. Neth Heart J 20, 439–446 (2012). https://doi.org/10.1007/s12471-012-0302-x

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  • DOI: https://doi.org/10.1007/s12471-012-0302-x

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