Abstract
Overproduction and accumulation of melanin cause a number of skin diseases. The inhibitors of tyrosinase are important for the treatment of skin diseases associated with hyper-pigmentation after UV exposure and application in cosmetics for whitening and depigmentation. Reactive oxygen species (ROS) including hydrogen peroxide are generated by chemical substances and metabolic intermediates and cause various diseases including cancer and heart diseases. We have isolated four different lactic acid bacteria (LAB) strains from dairy cow feces and investigated the tyrosinase inhibition and anti-oxidative effects of culture filtrates prepared from the isolated bacteria, which are designated as EA3, EB2, PC2, and PD3. To investigate optimal culture conditions isolated LAB strains, the measurements of tyrosinase inhibitory and anti-oxidative activities were performed. The results of tyrosinase inhibitory activities revealed that Enterococcus sp. EA3 showed about 65% at culture conditions (14 h, 30 °C, pH 8, and 0% NaCl), Enterococcus sp. EB2 about 65% at culture conditions (12 h, 30 °C, pH 9, and 0% NaCl), Pediococcus sp. PC2 about 80% at culture conditions (20 h, 30 °C, pH 6, and 0% NaCl), and Pediococcus sp. PD3 about 80% at culture conditions (20 h, 30 °C, pH 8, and 0% NaCl), respectively. In addition, anti-oxidative activities against four different LAB strains showed approximately more than 30% at optimal conditions for the measurements of tyrosinase inhibitory activities. From the results, we have suggested that the isolated four LAB strains could be useful for a potential agent for developing anti-oxidants and tyrosinase inhibitors.
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References
Chang T-S (2009) An updated review of tyrosinase inhibitors. Int J Mol Sci 10(6):2440–2475
Parvez S, Kang M, Chung HS, Bae H (2007) Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries. Phytother Res 21(9):805–816
Sánchez-Ferrer Á, Rodríguez-López JN, García-Cánovas F, García-Carmona F (1995) Tyrosinase: a comprehensive review of its mechanism. Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular Enzymology 1247(1):1–11
Nerya O, Vaya J, Musa R, Izrael S, Ben-Arie R, Tamir S (2003) Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. J Agric Food Chem 51(5):1201–1207
Fu B, Li H, Wang X, Lee FS, Cui S (2005) Isolation and identification of flavonoids in licorice and a study of their inhibitory effects on tyrosinase. J Agric Food Chem 53(19):7408–7414
Gadd G (1980) Melanin production and differentiation in batch cultures of the polymorphic fungus Aureobasidium pullulans. FEMS Microbiol Lett 9(3):237–240
Bell AA, Wheeler MH (1986) Biosynthesis and functions of fungal melanins. Annu Rev Phytopathol 24(1):411–451
Zimmerman W, Blanchette R, Burnes T, Farrell R (1995) Melanin and perithecial development in Ophiostoma piliferum. Mycologia:857–863
Priestley GC (1993) Molecular aspects of dermatology, vol 3. Wiley
Martinez MV, Whitaker JR (1995) The biochemistry and control of enzymatic browning. Trends Food Sci Technol 6(6):195–200
Funasaka Y, Komoto M, Ichihashi M (2000) Depigmenting effect of α-tocopheryl ferulate on normal human melanocytes. Pigment Cell Res 13(s8):170–174
Rackova L, Oblozinsky M, Kostalova D, Kettmann V, Bezakova L (2007) Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids. J Inflamm 4(1):1
Finkel T, Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408(6809):239–247
Senthil K, Aranganathan S, Nalini N (2004) Evidence of oxidative stress in the circulation of ovarian cancer patients. Clin Chim Acta 339(1):27–32
Galvan I, Solano F (2009) The evolution of eu-and pheomelanic traits may respond to an economy of pigments related to environmental oxidative stress. Pigment cell & melanoma research 22(3):339–342
Galván I, Alonso-Alvarez C (2009) The expression of melanin-based plumage is separately modulated by exogenous oxidative stress and a melanocortin. Proc R Soc Lond B Biol Sci 276(1670):3089–3097
Jimenez-Cervantes C, Solano F, Kobayashi T, Urabe K, Hearing VJ, Lozano JA, Garcia-Borron JC (1994) A new enzymatic function in the melanogenic pathway. The 5, 6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1). J Biol Chem 269(27):17993–18000
Giraffa G, Chanishvili N, Widyastuti Y (2010) Importance of lactobacilli in food and feed biotechnology. Res Microbiol 161(6):480–487
Arihara K, Ota H, Itoh M, Kondo Y, Sameshima T, Yamanaka H, Akimoto M, Kanai S, Miki T (1998) Lactobacillus acidophilus group lactic acid bacteria applied to meat fermentation. J Food Sci 63(3):544–547
Hammes W, Hertel C (1998) New developments in meat starter cultures. Meat Sci 49:S125–S138
Pomerantz SH (1963) Separation, purification, and properties of two tyrosinases from hamster melanoma. J Biol Chem 238(7):2351–2357
Dietz BM, Kang Y-H, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Farnsworth NR, Mesecar AD, van Breemen RB (2005) Xanthohumol isolated from Humulus lupulus inhibits menadione-induced DNA damage through induction of quinone reductase. Chem Res Toxicol 18(8):1296–1305
Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26(9):1231–1237
Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47(3):469–474
Lim TY, Lim YY, Yule CM (2009) Evaluation of antioxidant, antibacterial and anti-tyrosinase activities of four Macaranga species. Food Chem 114(2):594–599
Fawole OA, Makunga NP, Opara UL (2012) Antibacterial, antioxidant and tyrosinase-inhibition activities of pomegranate fruit peel methanolic extract. BMC Complement Altern Med 12(1):1
Lai HY, Lim YY, Tan SP (2009) Anti-oxidative, tyrosinase inhibiting and antibacterial activities of leaf extracts from medicinal ferns. Biosci Biotechnol Biochem 73(6):1362–1366
Huang H-C, Huang W-Y, Chiu S-H, Ke H-J, Chiu S-W, Wu S-Y, Kuo F-S, Chang T-M (2011) Antimelanogenic and anti-oxidative properties of Bifidobacterium bifidum. Arch Dermatol Res 303(7):527–531
Li S, Zhao Y, Zhang L, Zhang X, Huang L, Li D, Niu C, Yang Z, Wang Q (2012) Antioxidant activity of Lactobacillus plantarum strains isolated from traditional Chinese fermented foods. Food Chem 135(3):1914–1919
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This work was supported by the Research Grant of Pukyong National University (year 2016).
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Ji, K., Cho, Y.S. & Kim, Y.T. Tyrosinase Inhibitory and Anti-oxidative Effects of Lactic Acid Bacteria Isolated from Dairy Cow Feces. Probiotics & Antimicro. Prot. 10, 43–55 (2018). https://doi.org/10.1007/s12602-017-9274-x
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DOI: https://doi.org/10.1007/s12602-017-9274-x