Abstract
Based on historic, retrospective data, most surgeons recommend mastectomy for women with multiple ipsilateral breast cancers (MIBC) due to a perceived prohibitively high risk of local recurrence. More recent retrospective studies, however, have documented acceptable local recurrence rates in women with MIBC who have undergone breast conservation with lumpectomy and radiation therapy. The recent data suggest that earlier detection, improved margin analysis, and increased use and efficacy of targeted therapies all contribute to the decreased risk of local recurrence when compared to rates historically documented in this MIBC population. Appropriate surgical management for MIBC is of growing importance. Pre-operative identification of MIBC has increased in the past decade due to the increased use of MRI and improved mammographic and sonographic sensitivity. Review of the current literature supports the use breast conservation with one or more partial mastectomies and sentinel node biopsy in appropriately selected patients with MIBC.
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Rosenkranz, K. Multiple Ipsilateral Breast Cancers: Current Strategies for Surgical Management. Curr Breast Cancer Rep 4, 148–152 (2012). https://doi.org/10.1007/s12609-012-0075-7
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DOI: https://doi.org/10.1007/s12609-012-0075-7