Skip to main content
SpringerLink
Log in

Bone Scintigraphy and Tenofovir-Induced Osteomalacia in Chronic Hepatitis B

  • Interesting Image
  • Published:
Nuclear Medicine and Molecular Imaging Aims and scope Submit manuscript

A Correction to this article was published on 19 November 2018

This article has been updated

Abstract

Tenofovir, used in the treatment of chronic hepatitis B and HIV, is known for its side effects on the kidneys and bones. We share interesting images of a patient with tenofovir-induced osteomalacia on Technetium-99 m hydroxymethyelene (Tc-99 m HDP) bone scintigraphy. Pattern recognition of this bone scintigraphy and correlation with the clinical history is essential to avoid misdiagnosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Change history

  • 19 November 2018

    The original version of this article unfortunately contained a mistake. The presentation of the author names was incorrect. The correct information is given here.

  • 19 November 2018

    The original version of this article unfortunately contained a mistake. The presentation of the author names was incorrect. The correct information is given here.

References

  1. Magalhaes-Costa P, Matos L, Barreiro P, Chagas C. Fanconi syndrome and chronic renal failure in a chronic hepatitis B monoinfected patient treated with tenofovir. Rev Esp Enferm Dig. 2015;107:512–4.

    PubMed  Google Scholar 

  2. Hall AM, Hendry BM, Nitsch D, Connolly JO. Tenofovir-associated kidney toxicity in HIV infected patients: a review of the evidence. Am J Kidney Dis. 2011;57:773–80.

    Article  CAS  Google Scholar 

  3. Martinez MVG, Gallardo FG, Pirogova T, Garcia-Samaniego J. Bone scintigraphy and secondary osteomalacia due to nephrotoxicity in a chronic hepatitis B patient treated with tenofovir. Rev Esp Med Nucl Imagen Mol. 2014;33:103–5.

    Google Scholar 

Download references

Acknowledgment

The authors would like to thank the Director-General of Health Malaysia for the permission to publish this paper.

Author information

Authors and Affiliations

  1. Department of Nuclear Medicine, Penang Hospital, Jalan Residensi, 10990, Georgetown, Penang, Malaysia

    Alex Khoo Cheen Hoe & Lee Yeong Fong

Authors
  1. Alex Khoo Cheen Hoe
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lee Yeong Fong
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Alex Khoo Cheen Hoe.

Ethics declarations

Conflict of Interest

Alex Khoo Cheen Hoe and Lee Yeong Fong declare that they have no conflict of interest.

Ethical Statement

The study was approved by an institutional review board or equivalent and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. The subject in the study gave written informed consent.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Hoe, A.K.C., Fong, L.Y. Bone Scintigraphy and Tenofovir-Induced Osteomalacia in Chronic Hepatitis B. Nucl Med Mol Imaging 51, 195–196 (2017). https://doi.org/10.1007/s13139-016-0395-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13139-016-0395-z

Keywords

Search

Navigation