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Gastroparesis post-laparoscopic cholecystectomy in diabetic patients

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Abstract

Impairment of gastric emptying is well recognized in patients with diabetes mellitus. The aim of this study was to investigate the influencing factors for gastroparesis syndrome development after laparoscopic cholecystectomy in diabetic patients. This is a case–control study. Clinical data were collected retrospectively for 462 diabetic patients who underwent laparoscopic cholecystectomy from 2008 to 2013. We retrospectively analyzed the incidence of gastroparesis syndrome, clinical features, course of disease, and risk factors. The result showed strong positive relation between the diabetes duration, dose of insulin, patient age, other diabetes complications, and the incidence of gastroparesis. Gastroparesis is not uncommon post-laparoscopic cholecystectomy in diabetic patients.

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References

  1. Kassander P (1958) Asymptomatic gastric retention in diabetics (gastroparesis diabeticorum). Ann Intern Med 48(4):797–812

    Article  CAS  PubMed  Google Scholar 

  2. Kravetz RE (1965) Gastroparesis diabeticorum. Gastrointest Endosc 12(2):22–24

    CAS  PubMed  Google Scholar 

  3. Malagelada JR, Rees WDW, Mazzotta LJ, Go VLW (1980) Gastric motor abnormalities in diabetic and postvagotomy gastroparesis: effect of metoclopramide and bethanechol. Gastroenterology 78(2):286–293

    CAS  PubMed  Google Scholar 

  4. Hornbuckle KJLB (2000) The diagnosis and work-up of the patient with gastroparesis. J Clin Gastroenterol 30:117–124

    Article  CAS  PubMed  Google Scholar 

  5. Jung HK, Choung RS, Locke GR 3rd, Schleck CD, Zinsmeister AR, Szarka LA et al (2009) The incidence, prevalence, and outcomes of patients with gastroparesis in Olmsted County, Minnesota, from 1996 to 2006. Gastroenterology 136:1225–1233

    Article  PubMed  Google Scholar 

  6. Maleki D, Locke GR 3rd, Camilleri M, Zinsmeister AR, Yawn BP, Leibson C et al (2000) Gastrointestinal tract symptoms among persons with diabetes mellitus in the community. Arch Intern Med 160:2808

    Article  CAS  PubMed  Google Scholar 

  7. Parkman HP, Camilleri M, Farrugia G, McCallum RW, Bharucha AE, Mayer EA et al (2010) Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting. Neurogastroenterol Motil 22:113–133

    Article  CAS  PubMed  Google Scholar 

  8. Parkman HP, Hasler WL, Fisher RS (2004) American Gastroenterological Association medical position statement: diagnosis and treatment of gastroparesis. Gastroenterology 127(5):1589–1591

    Article  PubMed  Google Scholar 

  9. Ibrarullah M, Mittal BR, Agarwal DK, Das BK, Kaushik SP (1994) Gastric emptying in patients with gallstone disease with or without dyspepsia: effect of cholecystectomy. Austr NZ J Surg 64:247–250

    Article  CAS  Google Scholar 

  10. Parkman HP, Yates K, Hasler WL, Nguyen L, Pasricha PJ, Snape WJ et al (2013) Cholecystectomy and clinical presentations of gastroparesis. Dig Dis Sci 58(4):1062–1073

    Article  PubMed  Google Scholar 

  11. Bytzer P, Talley NJ, Leemon M, Young LJ, Jones MP, Horowitz M (2001) Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults. Arch Intern Med 161:1989–1996

    Article  CAS  PubMed  Google Scholar 

  12. Revicki DA, Rentz AM, Dubois D, Kahrilas P, Stanghellini V, Talley NJ et al (2004) Gastroparesis Cardinal Symptom Index (GCSI): development and validation of a patient reported assessment of severity of gastroparesis symptoms. Qual Life Res 13:833–844

    Article  PubMed  Google Scholar 

  13. Abell TL, Bernstein VK, Cutts T, Farrugia G, Forster J, Hasler WL et al (2006) Treatment of gastroparesis: a multidisciplinary clinical review. Neurogastroenterol Motil 18:263–283

    Article  CAS  PubMed  Google Scholar 

  14. Schvarcz E, Palmér M, Ingberg CM, Åman J, Berne C (1996) Increased prevalence of upper gastrointestinal symptoms in long-term type 1 diabetes mellitus. Diabet Med 13:478–481

    Article  CAS  PubMed  Google Scholar 

  15. Enck P, Rathmann W, Spiekermann M, Czerner D, Tschöpe D, Ziegler D et al (1994) Prevalence of gastrointestinal symptoms in diabetic patients and non-diabetic subjects. Z Gastroenterol 32:637–641

    CAS  PubMed  Google Scholar 

  16. Jones KL, Russo A, Stevens JE, Wishart JM, Berry MK, Horowitz M (2001) Predictors of delayed gastric emptying in diabetes. Diabetes Care 24:1264–1269

    Article  CAS  PubMed  Google Scholar 

  17. Horowitz M, O’Donovan D, Jones KL, Feinle C, Rayner CK, Samsom M (2002) Gastric emptying in diabetes: clinical significance and treatment. Diabet Med 19:177–194

    Article  CAS  PubMed  Google Scholar 

  18. Stevens JE, Gilja OH, Gentilcore D, Hausken T, Horowitz M, Jones KL (2011) Measurement of gastric emptying of a high-nutrient liquid by 3D ultrasonography in diabetic gastroparesis. Neurogastroenterol Motil 23:e114–e220

    Article  Google Scholar 

  19. Deeb F, Lacy B, Yoo H, Mitchell A, Ravich W (2001) Gastroparesis: a risk factor for cholecystectomy? Am J Gastroenterol 96:S51–S52

    Article  Google Scholar 

  20. Soykan I, Sivri B, Sarosiek I, Kiernan B, McCallum RW (1998) Demography, clinical characteristics, psychological and abuse profiles, treatment, and long-term follow-up of patients with gastroparesis. Dig Dis Sci 43:2398–2404

    Article  CAS  PubMed  Google Scholar 

  21. O’Donovan D, Hausken T, Lei Y, Russo A, Keogh J, Horowitz M et al (2005) Effect of aging on transpyloric flow, gastric emptying, and intragastric distribution in healthy humans-impact on glycemia. Dig Dis Sci 50:671–676

    Article  PubMed  Google Scholar 

  22. Madsen JL, Graff J (2004) Effects of ageing on GI motor function. Age Ageing 33:154–159

    Article  PubMed  Google Scholar 

  23. Hellmig S, Von Schoning F, Gadow C, Katsoulis S, Hedderich J, Fölsch UR et al (2006) Gastric emptying time of fluids and solids in healthy subjects determined by 13C breath tests: influence of age, sex and body mass index. J Gastroenterol Hepatol 21:1832–1838

    Article  PubMed  Google Scholar 

  24. Sanaka M, Yamamoto T, Anjiki H, Osaki Y, Kuyama Y (2006) Is the pattern of solid phase-gastric emptying different between genders? Eur J Clin Invest 36:574–579

    Article  CAS  PubMed  Google Scholar 

  25. Borg J, Melander O, Johansson L, Uvnäs-Moberg K, Rehfeld JF, Ohlsson B (2009) Gastroparesis is associated with oxytocin deficiency, oesophageal dysmotility with hyperCCKemia, and autonomic neuropathy with hypergastrinemia. BMC Gastroenterol 9:17

    Article  PubMed  PubMed Central  Google Scholar 

  26. Elhadd TA, Al-Amoudi AA, Alzahrani AS (2007) Epidemiology, clinical and complications profile of diabetes in Saudi Arabia: a review. Ann Saudi Med 27(4):241–250

    Article  PubMed  Google Scholar 

  27. Keshavarzian A, Iber FL, Vaeth J (1987) Gastric emptying in patients with insulin-requiring diabetes mellitus. Am J Gastroenterol 82:29–35

    CAS  PubMed  Google Scholar 

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  1. Department of Surgery, Medical College-King Faisal University, P.O. Box 1164, Hofuf, Al-Hassa, 31982, Kingdom of Saudi Arabia

    Abdulrahman Saleh Al-Mulhim

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  1. Abdulrahman Saleh Al-Mulhim
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Correspondence to Abdulrahman Saleh Al-Mulhim.

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Dr. Abdulrahman Saleh Al-Mulhim has no conflict of interest.

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Al-Mulhim, A.S. Gastroparesis post-laparoscopic cholecystectomy in diabetic patients. Updates Surg 69, 89–93 (2017). https://doi.org/10.1007/s13304-017-0417-0

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  • DOI: https://doi.org/10.1007/s13304-017-0417-0

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