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Effect of postprandial moderate-intensity walking for 15-min on glucose homeostasis in type 2 diabetes mellitus patients

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Abstract

Aim

Diabetes patients usually have a low activity level and complain about lack of time. Therefore, we investigated the effect of short time, postprandial moderate-intensity exercise on glucose homeostasis in type 2 diabetes patients.

Methods

Eleven patients with type 2 diabetes were recruited. Patients spent the first day of the study without exercise (non-exercise day; NE day). In the second day, they walked at moderate-intensity (40% of the maximum heart rate reserve) for 15 min, 30 min after each meal (exercise day; E day). Glucose homeostasis was estimated by a continuous glucose monitor (CGM). All meals during the study were of standard composition. We compared NE day and E day concerning 24-h glucose homeostasis and 3 h postprandial glucose levels by the incremental area under the curve (iAUC) method. Medications were not changed during the study.

Results

The number of patients under basal supported oral therapy, intensive insulin therapy and oral hypoglycemic agents (OHA) were 5, 4 and 2, respectively. The blood glucose standard deviation over 24 h and the iAUC for the 24-h glycemic variability (NE day vs. E day; 34,765 [21,424–56,014] vs. 23,205 [15,323–39,779]) were smaller in E day than in NE day.

Conclusion

These results suggest that postprandial moderate-intensity walking, easily performable in daily life activities, was effective for improving glucose homeostasis. Further study should be performed to clarify the relationship between postprandial walk and drug therapy (insulin and OHA), including insulin secretory ability.

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Acknowledgements

The authors would like to express deep gratitude to the Emeritus Professor Y. Oshida and Professor T. Koike of the Department of Sports Medicine, Graduate School of Medicine, Nagoya University, for the excellent advice. The authors thank all patients who took part in this study.

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Authors and Affiliations

  1. Department of Rehabilitation, Ichinomiyanishi Hospital, Hira 1, Kaimei, Ichinomiya, Aichi, 494-0001, Japan

    Yuji Iida & Kazuhiko Tanaka

  2. Department of Sports Medicine, Graduate School of Medicine, Nagoya University, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan

    Yuji Iida

  3. Department of Endocrinology and Diabetes, Ichinomiyanishi Hospital, Hira 1, Kaimei, Ichinomiya, Aichi, 494-0001, Japan

    Soichi Takeishi, Nobutoshi Fushimi & Akihiro Mori

  4. The Graduate Center of Human Sciences, Aichi Mizuho College, 2-13, Shunko-cho, Mizuho-ku, Nagoya, Aichi, 467-0867, Japan

    Yuzo Sato

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  1. Yuji Iida
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  2. Soichi Takeishi
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  3. Nobutoshi Fushimi
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  4. Kazuhiko Tanaka
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  5. Akihiro Mori
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  6. Yuzo Sato
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Corresponding author

Correspondence to Yuji Iida.

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No potential conflicts of interest relevant to this article were reported.

Human rights statement

This study was approved by the local ethics committee at the Ichinomiyanishi Hospital (approval date: 19 May 2014; approval no. 201516). It was also registered with the UMIN Clinical Trials Registry (UMIN000014567).

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All patients provided written informed consent before participating in this study.

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Iida, Y., Takeishi, S., Fushimi, N. et al. Effect of postprandial moderate-intensity walking for 15-min on glucose homeostasis in type 2 diabetes mellitus patients. Diabetol Int 11, 383–387 (2020). https://doi.org/10.1007/s13340-020-00433-x

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  • DOI: https://doi.org/10.1007/s13340-020-00433-x

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