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Synthesis of new derivatives of pyrazol-chromeno[2,3-d]pyrimidine-ones by a one-pot three-component reaction

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Abstract

A new three-component reaction between salicylaldehydes, barbituric acid, pyrazolones, in the presence of para-toluenesulfonic acid, efficiently provides pyrazol-chromeno[2,3-d]pyrimidine-ones derivatives in good yields in ethanol/water at 70 °C. This multicomponent reaction showed high atom economy.

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Acknowledgments

We gratefully acknowledge financial support from the Iran National Science Foundation (INSF) and Research Council of Razi University.

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Authors and Affiliations

  1. Department of Chemistry, Razi University, 67149-67346, Kermanshah, Iran

    Ebrahim Soleimani, Manizheh Ghanbarian & Parisa Saei

  2. Department of Chemistry, College of Sciences, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran

    Ebrahim Soleimani

  3. Department of Biology, Razi University, 67149-67346, Kermanshah, Iran

    Mojtaba Taran

Authors
  1. Ebrahim Soleimani
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  2. Manizheh Ghanbarian
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  3. Parisa Saei
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  4. Mojtaba Taran
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Correspondence to Ebrahim Soleimani.

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Soleimani, E., Ghanbarian, M., Saei, P. et al. Synthesis of new derivatives of pyrazol-chromeno[2,3-d]pyrimidine-ones by a one-pot three-component reaction. J IRAN CHEM SOC 12, 2227–2232 (2015). https://doi.org/10.1007/s13738-015-0701-1

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  • DOI: https://doi.org/10.1007/s13738-015-0701-1

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