Abstract
Disclaimer. Although the research described in this manuscript has been funded wholly or in part by the EPA, Contract #68D10135, it has not been subjected to the Agency's review and therefore does not necessarily reflect the views of the Agency; no official endorsement should be inferred.
Cyanides are ‘priority pollutants’ under the Clean Water Act. A number of Superfund sites, particularly mining and minerals processing sites, have released cyanide wastes to the environment. Free cyanide is present in water from the dissolution of compounds such as sodium cyanate, potassium cyanide, and hydrogen cyanide. The toxicity and fate of cyanide breakdown products, either during treatment or during natural degradation, is poorly understood. Aqueous species of particular concern are cyanate (CNO-), thiocyanate (SCN-), and cyanogen chloride (CNCl-). The toxicity of these compounds to aquatic life is highly variable depending on environmental conditions, including physicochemical and microbial influences. Information pertaining to aquatic plant uptake of these cyanide ligands could not be located in the literature, while only a few studies addressing terrestrial plant uptake of cyanide (and only in the form of NaCN) could be found. In order to adequately evaluate the environmental fate and associated toxicity to higher plants and animals, further studies need to be conducted.
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Acharya, V. N., Naik, S. R., Potnis, A. V., Bhallerao, R. A., Kaushik, R. V., Joshi, A. L., Desai, G. and Joshi, K.: 1986, J. Posthrad. Med. 32, 192.
American Public Health Association (APHA).: 1989, 'Standard Methods for the Examination of Water and Wastewater', 18th ed., APHA, Washington, DC., U.S.A.
Anderson, P. M., Sung, Y. and Fuchs, J. A.: 1990, FEMS Microbiol. 87, 247.
Boucabeille, C., Bories, A., Ollivier, P. and Michel, G.: 1994, Environ. Pollut. 84, 59.
Brown, P. D. and Morra, M. J.: 1993, J. Agric. Food Chem. 41, 978.
Cherryholmes, K. L., Cornils, W. J., McDonald, D. B. and Splinter, R. C.: 1983, Aquat. Tox. Haz. Assess. 7, 502.
Craigmill, A. L.: 1981, Univ. of CA Environ. Tox. Newsletter. 1, 3.
Dahlberg, P., Bergmark, A., Bjorcl, L., Bruce, A., Hambraeus, L. and Claesson, O.: 1984, Am. J. Clin. Nutr. 39, 416.
Dauchy, J. W., Waller, W. T. and Piwoni, M. D.: 1980. Bull. of Environ. Contam. Toxicol. 25, 194.
Eales, J. G. and Shostak, S.: 1983, Gen. Comp. Endocrinol. 51, 39.
Epstein, F. H., Maetz, J. and de Renzis, G.: 1973, Am. J. Physiol. 224, 1295.
Fallon, R. D., Cooper, D. A., Speece, R. and Henson, M.: 1991, Appl. Environ. Microb. 57, 1656.
Federal Register.: 1991, Testing Consent Order for Sodium Cyanide, 40 CFR, part 799, Vol. 56, No. 246. Washington, DC.
Garvin, C. F.: 1939, JAMA 112, 1125.
Green, W. L.: 1986, 'Antithyroid Compounds', in J. B. Lippincott (ed.), The Thyroid: A Fundamental and Clinical Text, Philadelphia, PA.
Green, T. L., Boswell, R. S. and Aldridge, D. W.: 1990, Am. Zool. 30.
Guilloton, M. and Karst, F.: 1987, J. Gen. Microbiol. 133, 655.
Guilloton, M. B., Lamblin, A. F., Kozliak, E. I., Gerami-Neiad, M., Tu, C., Silvermann, David, Anderson, P. M. and Fuchs, J. A.: 1993, J. of Bacteriol. 175, 1443.
Hasilik, A., Pohlmann, R. and Von Figure, K.: 1983, Biochem. J. 210, 795.
Heming, T. A., Thurston, R. V., Meyn, E. L. and Zajdel, R. K.: 1985, Trans. Am. Fish. Soc. 114, 890.
Heming, T. A. and Blumhagen, K. A.: 1989, Bull. Environ. Contam. Toxicol. 43, 363.
Hu, J. J., Luke, A., Chellani, M., Zirvi, K. A. and Lea, M. A. 1988, Biochem. Parmacol. 37, 2259.
Hu, J. J., Zirvi, K. A. and Lea, M. A.: 1989, Cancer, Biochem. Biophys. 10, 269.
Hu, J. J., Zirvi, K. A. and Lea, M. A.: 1990, Cancer, Chemother. Toxicol. 26, 269.
Kang, S. M. and Kim, D. J.: 1993, Biotechnol. Lett. 15, 201.
Katz, U., Lau, K. R., Ramos, M. M. P. and Ellory, J. C.: 1982, J. Membr, Biol. 66, 9.
Kevan, S. D. and Dixon, D. G.: 1991, Aquat. Toxicol. 19, 113.
Knowles, C. J.: 1988, CIBA Found. Symp. 40, 3.
Kononen, D. W.: 1988, Bull. Environ. Contam. Toxicol. 41, 371.
Koshishi, I., Shibayama, R., Morimoto, Y. and Imanari, T.: 1988, J. Pharmacobio-Dyn. 11, 730.
Koshishi, I. and Imanari, T.: 1990, J. Pharmacobio-Dyn. 13, 254.
Kunathai, S., Sholler, G. F., Celermajer, J. M., O'Halloran, M., Cartmill, T. B. and Nunn, G. R.: 1989, Pediatr. Cardiol. 10, 121.
Kunz, D. and Nagappan, O.: 1989, Appl. Environ. Microbiol. 55, 256.
Kunz, D. A., Nagappan, O., Silva-Avalos, J. and DeLong, G.: 1992, Appl. Environ. Microbiol. 58, 2022.
Lanno, R. P. and Dixon, G. D.: 1994, Environ. Tox. Chem. 13, 1423.
Leduc, G.: 1981, Cyanide in Biology, Academic Press, London, UK.
Lijinsky, W. and Kovatch, R. M.: 1989, Toxicol. Ind. Health 5, 25.
Lindahl, M. L., Svensson, A. and Lijas, A.: 1993, Proteins 15, 177.
Melzer, M. A., Christian, R. T., Dooley, J. F., Schumann, B., Su, H. L. and Samuels, S.: 1983, Mutat. Res. 116, 281.
Nagasawa, H., Yanai, R., Nakajima, Y., Nakimi, H., Kikuyama, S. and Shiota, K.: 1980, Eur. J. Cancer 16, 473.
Ohya, T. and Kanno, S.: 1987, J. Pharm. Sci. 76.
Paruchuri, Y. L., Shivaraman, N. and Kumaran, P.: 1990, Environ. Pollut. 68, 15.
Pollock, J. R. and Goff, H. M.: 1992, Biochim. Biophys. Acta 1159, 279.
Poulton, J. E. and Li, C. P.: 1994, Plant Physiol. 104, 29.
Rivera Sh., M., Dunin-Borkowski, P., Leon-Velarde, F., Huicho, L., Vargas, M. and Monge, C. C.: 1991, Basic Life Sci. 49, 439.
Roberts, K. A. and Harding, J. J.: 1990, Exp. Eye Res. 50, 157.
Sax, I. N.: 1992, in R. J. Lewis (ed.), Dangerous Properties of Industrial Materials, 8th edition, Vol. III. Nostrand Reinhold, New York, NY, U.S.A.
Serrano, O., Lopeez, R. and Palomares, J.: 1988, J. Anal. Toxicol. 12, 307.
Shenouda, G., Hutchinson, M., Noa, A. and Panasci, L.: 1993, J. Surg. Oncol. 52, 110.
Silva-Avalos, J., Richmond, M. G., Nagappan, O. and Kunz, D. A.: 1990, Appl. Environ. Microbiol. 56, 3664.
Smith, R. P.: 1973, Proceedings of the Society of Exp. Biol. Med. 142, 1041.
Speyer, M. R. and Raymond, P.: 1988, Environ. Toxicol. Chem. 7, 565.
Srivastava, V. K., Varshney, N. and Jaiswal, A.: 1993, Indian J. Exp. Biol. 31, 83.
Stelmasynska, T.: 1986, Int. J. Biochem. 18, 1107.
Teisseire, B. P., Vieilledent, C. C., Teisseire, L. J., Vallez, M. O., Herigault, R. A. and Laurent, D. N.: 1986, J. Appl. Physiol. 60, 1145.
U.S. Environmental Protection Agency.: 1983, Methods for Chemical Analysis of Water and Wastes, EPA-600/4-79-020, Washington, DC.
U.S. Environmental Protection Agency.: 1990, Sodium Cyanide risk Management Report, Washington, DC.
Wallace, A., Cha, J. W. and Mueller, R. T.: 1977, Comm. Soil. Sci. Plant Anal. 8, 709.
Wallace, A., Romney, E. M., Mueller, R. T. and Soufi, S. M.: 1981, Soil Sci. 132, 114.
White, J. M., Jones, D. D., Huang, D. and Gauthier, J. J.: 1988, J. Ind. Microb. 3, 263.
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Boening, D.W., Chew, C.M. A critical review: general toxicity and environmental fate of three aqueous cyanide ions and associated ligands. Water, Air, & Soil Pollution 109, 67–79 (1999). https://doi.org/10.1023/A:1005005117439
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DOI: https://doi.org/10.1023/A:1005005117439