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Characterizing QALYs by Risk Neutrality

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Abstract

This paper shows that QALYs can be derived from more elementary conditions than thought hitherto in the literature: it suffices to impose risk neutrality for life years in every health state. This derivation of QALYs is appealing because it does not require knowledge of concepts from utility theory such as utility independence. Therefore our axiomatization greatly facilitates the assessment of the normative (non)validity of QALYs in medical decision making. Moreover, risk neutrality can easily be tested in experimental designs, which makes it straightforward to assess the descriptive (non)validity of QALYs.

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References

  • Allais, Maurice. (1953). “Le Comportement de l';Homme Rationnel devant le Risque: Critique des Postulats et Axiomes de l'Ecole Américaine,” Econometrica 21, 503–546.

    Google Scholar 

  • Bleichrodt, Han. (1995). “QALYs and HYEs: Under What conditions Are They Equivalent?” Journal of Health Economics 14, 17–37.

    Google Scholar 

  • Bleichrodt, Han, and John Quiggin. (1997). “Characterizing QALYs Under a General Rank Dependent Utility Model,” Journal of Risk and Uncertainty 15, 151–165.

    Google Scholar 

  • Edwards, Ward. (1992, Ed.), Utility Theories: Measurement and Applications. Dordrecht: Kluwer Academic Publishers.

    Google Scholar 

  • Eeckhoudt, Louis. (1996). “Expected Utility Theory: Is It Normative or Simply ‘Practical’?”, Medical Decision Making 16, 12–13.

    Google Scholar 

  • Johannesson, Magnus. (1995). “Quality-Adjusted Life-Years Versus Healthy-Years Equivalents: A Comment,” Journal of Health Economics 14, 9–16.

    Google Scholar 

  • Johannesson, Magnus, and Per-Olov Johansson. (1996). “To Be, or not to Be, That Is the Question: An Empirical Study of the WTP for an Increased Life Expectancy at an Advanced Age,” Journal of Risk and Uncertainty 13, 163–174.

    Google Scholar 

  • Keeney, Ralph, and Howard Raiffa. (1976). “Decisions with Multiple Objectives.” New York: Wiley; (Second edition, 1993 Cambridge: Cambridge University Press).

    Google Scholar 

  • Loomes, Graham, and Lynda McKenzie. (1989). “The Use of QALYs in Health Care Decision Making,” Social Science and Medicine 28, 299–308.

    Google Scholar 

  • Machina, Mark J. (1982). “ ‘Expected Utility’ Analysis without the Independence Axiom,” Econometrica 50, 277–323.

    Google Scholar 

  • McNeil Barbara J., Ralph Weichselbaum, and Stephen G. Pauker. (1978). Fallacy of the Five-Year Survival in Lung Cancer, New England Journal of Medicine 299, 1397–1401.

    Google Scholar 

  • Miyamoto, John M., and Stephen A. Eraker. (1988). “A Multiplicative Model of the Utility of Survival Duration and Health Quality,” Journal of Experimental Psychology 117, 3–20.

    Google Scholar 

  • Moore, Michael J., and W. Kip Viscusi. (1990). “Models for Estimating Discount Rates for Long-term Health Risks Using Labor Market Data,” Journal of Risk and Uncertainty 3, 381–401.

    Google Scholar 

  • Peters, Hans J.M. (1992). Axiomatic Bargaining Theory. Dordrecht: Kluwer Academic Publishers.

    Google Scholar 

  • Pliskin, Joseph S., Donald S. Shepard, and Milton C. Weinstein. (1980). “Utility Functions for Life Years and Health Status,” Operations Research 28, 206–24.

    Google Scholar 

  • Stiggelbout Anne M., et al. (1994). “Utility Assessment in Cancer Patients: Adjustment of Time Tradeoff Scores for the Utility of Life Years and Comparison with Standard Gamble Scores,” Medical Decision Making 14, 82–90.

    Google Scholar 

  • Torrance George W., and David Feeny. (1989). “Utilities and Quality-Adjusted LifeYears,” International Journal of Technology Assessment in Health Care 5, 559–575.

    Google Scholar 

  • Viscusi, W. Kip, and Michael J. Moore. (1989). “Rates of Time Preference and Valuations of the Duration of Life,” Journal of Public Economics 38, 297–317.

    Google Scholar 

  • von Neumann, John, and Oskar Morgenstern. (1947). Theory of Games and Economic Behavior. Princeton: Princeton University Press.

    Google Scholar 

  • von Winterfeldt, Ditmar, and Ward Edwards. (1986). Decision Analysis and Behavioral Research. Cambridge: Cambridge University Press.

    Google Scholar 

  • Weinstein, Milton. C., et al. (1980). Clinical Decision Analysis. Philadelphia: Saunders.

    Google Scholar 

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Bleichrodt, H., Wakker, P. & Johannesson, M. Characterizing QALYs by Risk Neutrality. Journal of Risk and Uncertainty 15, 107–114 (1997). https://doi.org/10.1023/A:1007726117003

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