Skip to main content
Log in

Chemical Pathways of Degradation of the Bradykinin Analog, RMP-7

  • Note
  • Published:
Pharmaceutical Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

REFERENCES

  1. T. Inamura, T. Nomura, R. T. Bartus, K. L. Black. Intracarotid infusion of RMP-7, a method for selective drug delivery to brain tumors. J. Neurosurgery 81:752–758 (1994).

    Google Scholar 

  2. K. A. Conners, G. L. Amidon and V. J. Stella. “The Chemical Stability of Pharmaceuticals, A Handbook for Pharmacists,” Second Edition, John Wiley and Sons, New York, 1986, pp. 787–790.

    Google Scholar 

  3. D. M. Johnson, R. A. Pritchard, W. F. Taylor, D. Conley, G. Zuniga, and K. G. McGreevy. Degradation of the LH-RH analog nafarelin acetate in aqueous solution. Int. J. Pharm. 31:125–129 (1986).

    Google Scholar 

  4. K. C. Lee, Y. J. Lee, H. M. Song, C. J. Chun, and P. P. Deluca. Degradation of synthetic salmon calcitonin in aqueous solution. Pharm. Res. 9:1521–1523 (1992).

    Google Scholar 

  5. J. W. VanNispen. In D. D. Breimer and P. Speiser (eds.), Topics in Pharmaceutical Sciences 1987, Elsevier, Amsterdam, 1987, pp. 293–307.

    Google Scholar 

  6. V. J. Helm and B. W. Muller. Stability of gonadorelin and triptorelin in aqueous solution. Pharm. Res. 7:1253–1255 (1990).

    Google Scholar 

  7. S. M. Steinberg and J. L. Bada. Peptide decomposition in the neutral pH region via the formation of diketopiperazines. J. Org. Chem. 48:2298–2300 (1983).

    Google Scholar 

  8. N. F. Sepetov, M. A. Krymsky, M. V. Ovchinnikov, Z. D. Bespalova, O. L. Isakova, M. Soucek, and M. Lebl. Rearrangement, racemization and decomposition of peptides in aqueous solution. Peptide Res. 4:308–313 (1991).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Straub, J.A., Akiyama, A., Parmar, P. et al. Chemical Pathways of Degradation of the Bradykinin Analog, RMP-7. Pharm Res 12, 305–308 (1995). https://doi.org/10.1023/A:1016203731682

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1016203731682

Navigation