Abstract
Haematococcus pluvialis was mutated by UV or ethyl methanesulphonate. Mutants resistant to nicotine, diphenylamine, fluridone or norflurazon were then selected. Several nicotine-resistant mutants showed increased (1.9% to 2.5% vs. 1.2% w/w) astaxanthin production. Mutants maintained high astaxanthin production over 4 months of repeated culture.
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Chen, Y., Li, D., Lu, W. et al. Screening and characterization of astaxanthin-hyperproducing mutants of Haematococcus pluvialis . Biotechnology Letters 25, 527–529 (2003). https://doi.org/10.1023/A:1022877703008
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DOI: https://doi.org/10.1023/A:1022877703008