Skip to main content
SpringerLink
Log in

Rearrangement of the Prefrontal Cortex Neural Activity in Both Hemispheres during Learning

  • Physiology
  • Published:
Doklady Biological Sciences Aims and scope Submit manuscript

Abstract

Neuronal activity of both right and left hemispheres of the rat prefrontal brain cortex was recorded in the two-ring maze during animal learning to operate in response to signals. At the beginning of learning, pairwise comparison of neural activity that accompanied correct and incorrect choice of the right and left sides showed significant differences in the left hemisphere and the lack of differences in the right one. With increasing percentage of correct choices during a session of learning, the differences in neuronal responses appeared in the right hemispheres and were reduced in the left one. The opposite trends in rearrangement of the total impulse activity are believed to be related to different roles of hemispheres in the construction of the internal behavioral model.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cohen, Y., Putrino, D., and Wilson, D.A., J. Physiol., 2015, vol. 593, no. 7, pp. 1701–1714.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  2. Oertel, V., Knochel, C., Rotarska-Jagiela, A., Schonmeyer, R., Lindner, M., van de Ven, V., Haenschel, C., Uhlhaas, P., Maurer, K., and Linden, D.E., J. Neurosci., 2010, vol. 30, no. 6, pp. 2289–2299.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  3. Manousopoulou, A., Saito, S., Yamamoto, Y., Al-Daghri, N.M., Ihara, M., Carare, R.O., and Garbis, S.D., J. Alzheim. Dis., 2016, vol. 51, no. 2, pp. 333–338.

    Article  Google Scholar 

  4. Tat, M.J. and Azuma, T., Laterality, 2016, vol. 21, no. 1, pp. 50–75.

    Article  PubMed  Google Scholar 

  5. Hirose, S., Chikazoe, J., Watanabe, T., Jimura, K., Kunimatsu, A., Abe, O., Ohtomo, K., Miyashita, Y., and Konishi, S., J. Neurosci., 2012, vol. 32, no. 26, pp. 9059–9065.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  6. Suzuki, T., Higashi, T., Takagi, M., and Sugawara, K., Neuroreport, 2013, vol. 24, no. 13, pp. 693–697.

    Article  PubMed  Google Scholar 

  7. Fokin, V.F., Bogolepova, I.N., Gutnik, B., Kobrin, V.I., and Shul’govskii, V.V., Rukovodstvo po funktsional’noi mezhpolusharnoi asimmetrii (The Handbook of the Functional Interhemispheric Asymmetry), Moscow: Nauchnyi Mir, 2009.

    Google Scholar 

  8. Filatova, E.V., Orlov, A.A., and Afanas’ev, S.V., Ros. Fiziol. Zh. im. I.M. Sechenova, 2016, vol. 102, no. 7, pp. 807–814.

    CAS  Google Scholar 

  9. Paxinos, G. and Watson, Ch., The Rat Brain in Stereotaxic Coordinates, Academic, 2006, 6th eition.

    Google Scholar 

  10. Filatova, E.V., Orlov, A.A., and Afanas’ev, S.V., Ros. Fiziol. Zh. im. I.M. Sechenova, 2014, vol. 100, no. 1, pp. 27–35.

    CAS  Google Scholar 

  11. Orlov, A.A. and Filatova, E.V., Ros. Fiziol. Zh. im. I. M. Sechenova, 2010. vol. 96, no. 6, pp. 640–643.

    CAS  Google Scholar 

  12. Sullivan, R.M., Stress, 2004, vol. 7, no. 2, pp. 131–143.

    Article  PubMed  CAS  Google Scholar 

  13. Denenberg, V.H., Behav. Brain Sci., 1981, vol. 4, pp. 1–49.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia

    A. A. Orlov, E. V. Filatova & S. V. Afanasyev

Authors
  1. A. A. Orlov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. V. Filatova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. V. Afanasyev
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. V. Filatova.

Additional information

Original Russian Text © A.A. Orlov, E.V. Filatova, S.V. Afanasyev, 2018, published in Doklady Akademii Nauk, 2018, Vol. 482, No. 1.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Orlov, A.A., Filatova, E.V. & Afanasyev, S.V. Rearrangement of the Prefrontal Cortex Neural Activity in Both Hemispheres during Learning. Dokl Biol Sci 482, 163–165 (2018). https://doi.org/10.1134/S0012496618050034

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0012496618050034

Search

Navigation