Skip to main content
SpringerLink
Log in

Apoptosis in Carcinogenesis and Chemotherapy

Apoptosis in cancer

  • Book
  • © 2009

Overview

Editors:
  1. George G. Chen

    1. Department of Surgery Shatin, Chinese University of Hong Kong Prince of Wales Hospital, Shatin, Hong Kong/PR China

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Paul B.S. Lai

    1. Department of Surgery Shatin, Chinese University of Hong Kong Prince of Wales Hospital, Shatin, Hong Kong/PR China

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Comprehensive review of recent development in apoptosis in major cancers and their chemotherapy
  • Translations of laboratory cancer research into emerging anti-cancer strategies

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (15 chapters)

  1. Front Matter

    Pages I-XXII
    Download chapter PDF

  2. Apoptotic Signaling Pathway and Resistance to Apoptosis in Breast Cancer Stem Cells

    • Prasanthi Karna, Lily Yang
    Pages 1-23

  3. Anti-Cancer Strategy of Transitional Cell Carcinoma of Bladder Based on Induction of Different Types of Programmed Cell Deaths

    • Jose A. Karam, Jer-Tsong Hsieh
    Pages 25-50

  4. Apoptosis in Carcinogenesis and Chemoherapy of the Uterine Cervix

    • Sakari Hietanen
    Pages 51-73

  5. Apoptosis in Colorectal Tumorigenesis and Chemotherapy

    • Shi Yu Yang, Kevin M. Sales, Marc C. Winslet
    Pages 75-109

  6. Apoptosis in Cutaneous Melanoma

    • Michael B. Nicholl, Dave S.B. Hoon
    Pages 111-125

  7. Apoptosis in Carcinogenesis and Chemotherapy – Esophageal Cancer

    • Yan Li, Robert C.G. Martin
    Pages 127-156

  8. Molecular Targets in Gastric Cancer and Apoptosis

    • Elizabeth K. Balcer-Kubiczek, Michael C. Garofalo
    Pages 157-192

  9. Apoptosis and the Tumor Microenvironment in Hematologic Malignancies

    • Danielle N. Yarde, Jianguo Tao
    Pages 193-218

  10. Bcl-2 Family Members in Hepatocellular Carcinoma (HCC) – Mechanisms and Therapeutic Potentials

    • Shihong Ma, George G. Chen, Paul B.S. Lai
    Pages 219-235

  11. Apoptosis in the Development and Treatment of Laryngeal Cancer: Role of p53, Bcl-2 and Clusterin

    • Maximino Redondo, Rafael Fùnez, Francisco Esteban
    Pages 237-249

  12. Cyclooxygenase 2 and its Metabolites: Implications for Lung Cancer Therapy

    • Kin Chung Leung, George G. Chen
    Pages 251-272

  13. Roles of Negative and Positive Growth Regulators in Nasopharyngeal Carcinoma

    • Mong-Hong Lee, Huiling Yang, Ruiying Zhao, Sai-Ching J. Yeung
    Pages 273-294

  14. Cellular Signaling Mechanisms in Pancreatic Apoptosis

    • Nawab Ali, Stewart MacLeod, R. Jean Hine, Parimal Chowdhury
    Pages 295-325

  15. Strategies to Circumvent Resistance to Apoptosis in Prostate Cancer Cells by Targeted Necrosis

    • Richard D. Dinnen, Daniel P. Petrylak, Robert L. Fine
    Pages 327-346

  16. Carcinogenesis and Therapeutic Strategies for Thyroid Cancer

    • Zhi-Min Liu, George G. Chen
    Pages 347-374

  17. Back Matter

    Pages 375-384
    Download chapter PDF
Back to top

Keywords

About this book

Although research on carcinogenesis has focused more on cellular proliferation than on cell death, yet understanding the mechanism of apoptosis may have important implications for cancer therapy. This book brings together experts from around the world who will discuss the common cancers encountered in clinical practice in the laboratory setting. During the induction of these common cancers, the role of apoptosis in cellular and molecular changes is emphasized, critically highlighting possible anti-cancer strategies. For those who are interested in carcinogenesis and for those who are seeking new approaches to anti-cancer therapy, this book is an important reference. It serves not only as a reference of the current understanding of apoptosis in common cancers but also an important bridge between the laboratory and clinical practice. The editors and contributors are to be congratulated in bringing together an important pool of up-to-date knowledge to light and further our interest in this exciting and expanding ?eld. Arthur K. C. Li Emeritus Professor of Surgery The Chinese University of Hong Kong v Preface The role of apoptosis in cancer development and emerging treatment strategies has rapidly expanded over the past few years. The novel discovery in the apoptotic pa- ways and their relevant molecules provides us not only the knowledge how tumors develop but also the opportunity to design new therapeutic tools to prevent or inhibit the growth of tumors with minimal side-effects. Undoubtedly, understanding the events involved at a molecular level can permit the manipulation of apoptosis for therapeutic purposes.

Editors and Affiliations

  • Department of Surgery Shatin, Chinese University of Hong Kong Prince of Wales Hospital, Shatin, Hong Kong/PR China

    George G. Chen, Paul B.S. Lai

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation