Overview
- Editors:
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Stefan Bröer
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Australian National University, Canberra, Australia
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Carsten A. Wagner
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University of Zurich, Zurich, Switzerland
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Table of contents (24 chapters)
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Front Matter
Pages i-xiii
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Introduction to membrane transport
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- Stefan Bröer, Carsten A. Wagner
Pages 1-25
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Renal Transport of Electrolytes and Acid-Base Equivalents
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Transporters of Trace elements and Biominerals
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- Michael D. Garrick, Laura M. Garrick
Pages 107-122
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Transporters of Energy Metabolites and Building Blocks
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Front Matter
Pages 133-133
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- Keiko Kobayashi, Takeyori Saheki
Pages 147-160
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- Nicola Longo, Cristina Amat Di San Filippo, Marzia Pasquali
Pages 161-174
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- Marc Foretz, Bernard Thorens
Pages 175-190
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- Janice Yang Chou, Brian C. Mansfield
Pages 191-205
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- Josep ChillarĂ³n, Joan Bertran, Manuel PalacĂn
Pages 207-231
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- Frans W. Verheijen, Grazia M. S. Mancini
Pages 233-239
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- Judith C. Fleming, Ellis J. Neufeld
Pages 241-248
About this book
Every cell and organism faces the problem of spaces, made up of the two leaflets of the lipid generating a confined space in which metabolic bilayer. The importance of traffic and signaling across membranes is reflected by the estimate and anabolic reactions take place and at the same time allowing entry and exit of metabo that 20% of all genes in the human genome encode membrane proteins. A failure of any of lites, ions, proteins, and signals across its bor der. Evolution has solved the problem by these proteins may have dramatic con se generating lipid membranes that contain trans quences for ceH function. In recent years much porters, ion channels, and receptors. In eukary attention has been paid to diseases resulting otic cells, this problem is exacerbated by the from nonfunctional ion channels ("chan presence of multiple organelles, which are con nelopathies"). Not surprisingly, many of these fined spaces in their own right. Even the lipid diseases affect the excitability of cells. membrane consists of two relatively separate Transporter diseases (perhaps coined "carrier vi PREFACE diseases") are more related to metabolic dis Each chapter is concluded by a summary, and eases, Transporters are frequently found at the most chapters also contain an overview of the beginning or the end of metabolic pathways clinical features of a particular transporter and as a result can have similar effects to disease. a missing enzyme.
Editors and Affiliations
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Australian National University, Canberra, Australia
Stefan Bröer
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University of Zurich, Zurich, Switzerland
Carsten A. Wagner