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Angiogenesis

From the Molecular to Integrative Pharmacology

  • Book
  • © 2000

Overview

Editors:
  1. Michael E. Maragoudakis

    1. University of Patras Medical School, Patras, Greece

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 476)

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-x
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  2. Introductory Comments

    1. Introductory Comments

      • Michael E. Maragoudakis
      Pages 1-4

  3. Angiogenic Factors and their Receptors

    1. Front Matter

      Pages 5-5
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    2. Examining New Models for the Study of Autocrine and Paracrine Mechanisms of Angiogenesis Through FGF2-Transfected Endothelial and Tumour Cells

      • Marco Presta, Marco Rusnati, Patrizia Dell’Era, Elena Tanghetti, Chiara Urbinati, Roberta Giuliani et al.
      Pages 7-34

    3. Tie-1 Receptor Tyrosine Kinase Endodomain Interaction with SHP2: Potential Signalling Mechanisms and Roles in Angiogenesis

      • Marrie B. Marron, David P. Hughes, Mark J. McCarthy, Nicholas P. J. Brindle, Eleanor R. Beaumont
      Pages 35-46

    4. On the Mechanism(s) of Thrombin Induced Angiogenesis

      • Michael E. Maragoudakis, Nikos E. Tsopanoglou
      Pages 47-55

    5. Endothelial Receptor Tyrosine Kinases involved in Blood Vessel Development and Tumor Angiogenesis

      • Georg Breier
      Pages 57-66

    6. Ontogeny of the Endothelial System in the Avian Model

      • Luc Pardanaud, Françoise Dieterlen-Lièvre
      Pages 67-78

  4. Regulation of Angiogenesis and Transduction Mechanisms Involved

    1. Front Matter

      Pages 79-79
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    2. The Role of Pericytes in Controlling Angiogenesis In Vivo

      • S. Egginton, A-L Zhou, O. Hudlická, M. D. Brown
      Pages 81-99

    3. Insights into the Vasodilation of Rat Retinal Vessels Evoked by Vascular Endothelial Growth Factor121 (VEGF121)

      • H.M. Hasséssian
      Pages 101-108

    4. Signal Transduction and Transcriptional Regulation of Angiogenesis

      • Yasufumi Sato, Mayumi Abe, Katsuhiro Tanaka, Chika Iwasaka, Nobuyuki Oda, Shinichi Kanno et al.
      Pages 109-115

    5. Differential Contribution of Bradykinin Receptors in Angiogenesis

      • Lucia Morbidelli, Astrid Parenti, Sandra Donnini, Fabrizio Ledda, Harris J. Granger, Marina Ziche
      Pages 117-128

    6. Sensitivity of Different Vascular Beds in the Eye to Neovascularization and Blood-Retinal Barrier Breakdown in VEGF Transgenic Mice

      • S. A. Vinores, N. L. Derevjanik, M. A. Vinores, N. Okamoto, P. A. Campochiaro
      Pages 129-138

    7. Revascularization of Ischemic Tissues With Sikvav and Neuropeptide Y (Npy)

      • Derrick S. Grant, Zofia Zukowska
      Pages 139-154

    8. Cellular Effects and Signalling Pathways Activated by the Anti-Coagulant Factor, Protein S, in Vascular Cells

      • Chryso Kanthou, Omar Benzakour
      Pages 155-166

  5. Role of Extracellular Matrix and Adhesion Molecules in Angiogenesis

    1. Front Matter

      Pages 167-167
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    2. Targeting Integrins αvβ3 and αvβ5 for Bloking Tumor-Induced Angiogenesis

      • C. Chandra Kumar, L. Armstrong, Z. Yin, M. Malkowski, E. Maxwell, He. Ling et al.
      Pages 169-180

    3. Suppression of Human Microvascular Endothelial Cell Invasion and Morphogenesis With Synthetic Matrixin Inhibitors

      • Meng-Chun Jia, Martin A. Schwartz, QingXiang Amy Sang
      Pages 181-194

  6. Inhibitors of Angiogenesis and their Mechanisms of Action

    1. Front Matter

      Pages 195-195
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Keywords

About this book

Proceedings of the 5th Biannual International Meeting on Angiogenesis: From the Molecular to Integrative Pharmacology, held July 1-7, 1999, in Crete, Greece.
Angiogenesis, as a vastly complex biological process, has challenged researchers from all basic scientific disciplines, including pharmacology, biochemistry, physiology, embryology and anatomy. The significance of this phenomenon for the study of disease states has also interested clinicians from a number of specialist fields. This multidisciplinary work reflects the growth of awareness of concepts such as angiogenesis based therapy, the enormous therapeutic and commercial potential of which has attracted major research and investment in recent years. This volume, which aims to bridge the gap between basic and clinical methodology and understanding, presents the most up-to-date developments in this field.

Editors and Affiliations

  • University of Patras Medical School, Patras, Greece

    Michael E. Maragoudakis

Bibliographic Information

  • Book Title: Angiogenesis

  • Book Subtitle: From the Molecular to Integrative Pharmacology

  • Editors: Michael E. Maragoudakis

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4615-4221-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2000

  • Hardcover ISBN: 978-0-306-46375-4Published: 30 June 2000

  • Softcover ISBN: 978-1-4613-6895-3Published: 13 November 2012

  • eBook ISBN: 978-1-4615-4221-6Published: 06 December 2012

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: X, 382

  • Topics: Oncology, Pharmacology/Toxicology, Dermatology, Ophthalmology, Biochemistry, general

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