Skip to main content
SpringerLink
Log in

Chiral Separations

  • Book
  • © 1988

Overview

Editors:
  1. D. Stevenson

    1. The Robens Institute of Industrial and Environmental Health and Safety, University of Surrey, Guildford, Surrey, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. I. D. Wilson

    1. ICI Pharmaceuticals, Macclesfield, Cheshire, UK

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. The Biological Importance of Chirality and Methods Available to Determine Enantiomers

    • D. Stevenson, G. A. Williams
    Pages 1-9

  3. Drug Analysis using High-Performance Liquid Chromatographic (HPLC) Chiral Stationary Phases: Where to Begin and Which to Use

    • Irving W. Wainer, Rose M. Stiffin, Ya-Qin Chu
    Pages 11-21

  4. Systematic Studies of Chiral Recognition Mechanisms

    • William H. Pirkle, Thomas C. Pochapsky, John A. Burke III, Kris C. Deming
    Pages 23-35

  5. A Note on Separation of Enantiomers of Oxyphenonium Bromide by High-Performance Liquid Chromatography

    • Karla G. Feitsma, Ben F. H. Drenth, Rokus A. de Zeeuw
    Pages 37-41

  6. The Use of Pirkle High-Performance Liquid Chromatography Phases in the Resolution of Enantiomers of Polycyclic Aromatic Hydrocarbon Metabolites

    • Michael Hall, Philip L. Grover
    Pages 43-54

  7. A Note on the Role of Solvents and Steric Factors in the Resolution of β-Blocker Drugs on Chiral Urea Phases

    • Nagaraja K. R. Rao, Robert C. Towill, Bindu Todd
    Pages 55-59

  8. A Note on Complexation of Dansyl Amino Acid Enantiomers by β-Cyclodextrin Studied by High Performance Liquid Chromatography and Fluorescence Measurements

    • David A. Briggs, Roger B. Homer, Russell Godfrey
    Pages 61-64

  9. A Note on Analytical and Preparative Chiral Resolution of Some Aminoalcohols by Ion-Pair High-Performance Liquid Chromatography

    • R. M. Gaskell, B. Crooks
    Pages 65-70

  10. Simultaneous Enantioselective Determination of Underivatized β-Blocking Agents and their Metabolites in Biological Samples by Chiral Ion-Pairing High-Performance Liquid Chromatography

    • T. Leemann, P. Dayer
    Pages 71-78

  11. Chiral Gas and High-Performance Liquid Chromatographic Analysis of Enantiomers of Fungicides and Plant Growth Regulators: Application in Fungal, Plant and Soil Metabolism Studies

    • T. Clark, A. H. B. Deas, K. Vogeler
    Pages 79-90

  12. Recent Developments in Enantiomer Separation by Complexation Gas Chromatography

    • Volker Schurig, Rainer Link
    Pages 91-114

  13. A Note on Use of Various Commercially Available Chiral Stationary Phases in Supercritical Fluid Chromatography

    • P. Macaudiere, M. Caude, R. Rosset, T. Tambute
    Pages 115-120

  14. Strategies for Optimising Chiral Separations in Drug Analysis

    • Anthony F. Fell, Terence A. G. Noctor
    Pages 121-125

  15. A Note on Further use of Computer Aided Chemistry to Predict Chiral Separations in Liquid Chromatography: Selecting the Most Appropriate Derivative

    • Ulf Norinder, E. Goran Sundholm
    Pages 127-130

  16. A Note on an Optical Rotation Detector for High-Performance Liquid Chromatography

    • D. M. Goodall, D. K. Lloyd
    Pages 131-133

  17. Prospects for Chiral Thin-Layer Chromatography

    • I. D. Wilson, R. J. Ruane
    Pages 135-143

  18. Back Matter

    Pages 145-206
    Download chapter PDF
Back to top

Keywords

About this book

This volume represents the proceedings of a two-day international meeting on chiral chromatography held at the University of Surrey between 3-4 September 1987. The meeting was jointly organized by the Chromatographic SOCiety and the Robens Institute of the University of Surrey in response to the burgeoning interest in this rapid maturing field of chromatography. Nowhere is this interest more evident than in the agrochemical and pharmaceutical industries where the implications of different pharmacological and toxicological activity for the individual enantiomers present in a racemic drug ol" insecticide is an increasing area of concern. Developments in the area of chiral separations are at last beginning to provide SCientists with the necessary tools to study how animals and man handle racemates and relate their obseIVations to the obseIVed biological effects of these substances. The development of robust and Simple methods for the separation of enantiomers will therefore have a profound Impact on safety evaluation and drug design. The meeting proved to be very successful. with over 160 delegates from thirteen countries in Europe and America present to learn from the experiences of experts in the field of chiral chromatography and to hear about the latest developments. Hopefully. in future symposia on chiral separations at the University of Surrey.

Editors and Affiliations

  • The Robens Institute of Industrial and Environmental Health and Safety, University of Surrey, Guildford, Surrey, UK

    D. Stevenson

  • ICI Pharmaceuticals, Macclesfield, Cheshire, UK

    I. D. Wilson

Bibliographic Information

  • Book Title: Chiral Separations

  • Editors: D. Stevenson, I. D. Wilson

  • DOI: https://doi.org/10.1007/978-1-4615-6634-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1988

  • Softcover ISBN: 978-1-4615-6636-6Published: 25 November 2012

  • eBook ISBN: 978-1-4615-6634-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIII, 206

  • Topics: Chromatography, Biomedicine general

Publish with us

Policies and ethics

Back to top

Search

Navigation