Skip to main content
SpringerLink
Log in

Chemical Mutagens

Principles and Methods for Their Detection Volume 1

  • Book
  • © 1971

Overview

Editors:
  1. Alexander Hollaender

    1. Division of Biology, Oak Ridge National Laboratory, Oak Ridge, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (11 chapters)

  1. Front Matter

    Pages i-xxvii
    Download chapter PDF

  2. Molecular Mechanisms of Mutations

    • Ernst Freese
    Pages 1-56

  3. Correlation Between Teratogenic and Mutagenic Effects of Chemicals in Mammals

    • Harold Kalter
    Pages 57-82

  4. The Mutagenicity of Chemical Carcinogens: Correlations, Problems, and Interpretations

    • Elizabeth C. Miller, James A. Miller
    Pages 83-119

  5. Effects on DNA: Chemical Methods

    • P. Brookes, P. D. Lawley
    Pages 121-144

  6. Physical-Chemical Methods for the Detection of the Effect of Mutagens on DNA

    • Bernard S. Strauss
    Pages 145-174

  7. Effects on DNA: Transforming Principle

    • Roger M. Herriott
    Pages 175-217

  8. Mutagen Screening with Virulent Bacteriophages

    • John W. Drake
    Pages 219-233

  9. Prophage Induction in Lysogenic Bacteria as a Method of Detecting Potential Mutagenic, Carcinogenic, Carcinostatic, and Teratogenic Agents

    • Bernard Heinemann
    Pages 235-266

  10. The Detection of Chemical Mutagens with Enteric Bacteria

    • Bruce N. Ames
    Pages 267-282

  11. Addendum to Chapter 9 Mutagenesis Studies with Escherichia coli Mutants with Known Amino Acid (and Base-Pair) Changes

    • C. Yanofsky
    Pages 283-287

  12. Mutation Induction in Yeast

    • R. K. Mortimer, T. R. Manney
    Pages 289-310

  13. Back Matter

    Pages xxix-lxviii
    Download chapter PDF
Back to top

Keywords

About this book

As editor I want especially to thank Dr. Ernst Freese for helpful co­ operation in preparing these volumes, and to express my appreclatlOn to Drs. Kurt Hirschhorn and Marvin Legator, the other members of the editorial board. Alexander Hollaender January 1971 Preface The purpose of these volumes is to encourage the development and ap­ plication of testing and monitoring procedures to avert significant human exposure to mutagenic agents. The need for protection against exposure to possibly mutagenic chemicals is only now coming to be generally realized. The recently issued Report of the Secretary's Commission on Pesticides and Their Possible Effects on Health (the Mrak Report-U.S. Department of Health, Education and Welfare, December 1969) has made an important start. Its Panel on Mutagenicity recommends that all currently used pesticides be tested for mutagenicity in several recently developed and relatively simple systems. Whether recommendations such as these are actually put into effect will depend on convincing government, industry, and the public that the problem is important, that the proposed tests would be effective, and that they can be conducted at a cost that is not prohibitive. Why is it important to screen environmental agents for mutagenic activity? To those who will read this book, the answer is self-evident. The sine qua non of all that we value and all that we are is our genetic heritage.

Editors and Affiliations

  • Division of Biology, Oak Ridge National Laboratory, Oak Ridge, USA

    Alexander Hollaender

Bibliographic Information

Publish with us

Policies and ethics

Back to top

Search

Navigation