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Genetic Predisposition to Cancer

  • Book
  • © 1996

Overview

Editors:
  1. Rosalind A. Eeles

    1. Cancer Genetics and Clinical Oncology, Institute of Cancer Research and Royal Marsden Hospital, Surrey, UK

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  2. Bruce A. J. Ponder

    1. CRC Human Cancer Genetics Research Group, University of Cambridge, UK

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  3. Douglas F. Easton

    1. CRC Genetic Epidemiology Unit, University of Cambridge, UK

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  4. Alan Horwich

    1. Academic Unit of Radiotherapy and Oncology, Institute of Cancer Research and Royal Marsden Hospital, Surrey, UK

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xix
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  3. Inherited Cancer Syndromes

    1. Front Matter

      Pages 57-57
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    2. Retinoblastoma: the paradigm for a genetically inherited cancer syndrome

      • John K. Cowell
      Pages 58-69

    3. Neurofibromatosis (NF) types 1 and 2

      • Susan M. Huson
      Pages 70-97

    4. Multiple endocrine neoplasia

      • Bruce A. J. Ponder
      Pages 98-104

    5. Wilms tumour and other genetic causes of renal cancer

      • Kathryn Pritchard-Jones
      Pages 105-122

    6. The Li-Fraumeni syndrome and the role of TP53 mutations in predisposition to cancer

      • Jillian M. Birch
      Pages 123-135

  4. Chromosome Fragility Syndromes and the Gorlin Syndrome

    1. Front Matter

      Pages 137-137
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    2. Malignant disease and variations in radiosensitivity in ataxia telangiectasia patients

      • A. M. R. Taylor, D. Hernandez, C. M. McConville, C. G. Woods, M. Stacey, P. Biggs et al.
      Pages 138-151

    3. Fanconi’s anaemia

      • Christopher G. Mathew
      Pages 152-163

    4. The Gorlin (nevoid basal cell carcinoma) syndrome

      • Peter A. Farndon
      Pages 164-184

    5. Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy: sun sensitivity, DNA repair defects and skin cancer

      • Colin F. Arlett, Alan R. Lehmann
      Pages 185-206

  5. The Common Cancers

    1. Front Matter

      Pages 207-207
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    2. Genetics and the common cancers

      • Richard S. Houlston, Julian Peto
      Pages 208-226

    3. Familial breast cancer

      • David E. Goldgar, Michael R. Stratton, Rosalind A. Eeles
      Pages 227-238

    4. The breast-ovarian cancer syndrome and BRCA1

      • Deborah Ford, Douglas F. Easton
      Pages 239-252
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Keywords

Editors and Affiliations

  • Cancer Genetics and Clinical Oncology, Institute of Cancer Research and Royal Marsden Hospital, Surrey, UK

    Rosalind A. Eeles

  • CRC Human Cancer Genetics Research Group, University of Cambridge, UK

    Bruce A. J. Ponder

  • CRC Genetic Epidemiology Unit, University of Cambridge, UK

    Douglas F. Easton

  • Academic Unit of Radiotherapy and Oncology, Institute of Cancer Research and Royal Marsden Hospital, Surrey, UK

    Alan Horwich

Bibliographic Information

  • Book Title: Genetic Predisposition to Cancer

  • Editors: Rosalind A. Eeles, Bruce A. J. Ponder, Douglas F. Easton, Alan Horwich

  • DOI: https://doi.org/10.1007/978-1-4899-4501-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media Dordrecht 1996

  • Softcover ISBN: 978-0-412-56580-9Published: 01 January 1996

  • eBook ISBN: 978-1-4899-4501-3Published: 11 November 2013

  • Edition Number: 1

  • Number of Pages: XIX, 407

  • Number of Illustrations: 22 b/w illustrations, 2 illustrations in colour

  • Topics: Oncology, Human Genetics

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