Overview
Provides basic as well as current scientific knowledge on neuropilins structure and function
Reader will learn about each major biological system, affected by neuropilins
Discusses potential medical implications
Presents a state-of-the art work for biomedical scientists
Includes supplementary material: sn.pub/extras
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Table of contents (13 chapters)
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Molecular Mechanisms of Neuropilin Mediated Signal Transduction
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Neuropilins as Regulators of Developmental and Immune Processes
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The Role of the Neuropilins in Cancer and in Immune Disorders
Keywords
About this book
This book covers basic research topics such as the structure-function relationships of neuropilins and mechanisms of neuropilin-mediated signal transduction, details the most important roles of the neuropilins in developmental biology, and addresses their roles in various conditions such as cancer and various eye diseases.
The two neuropilin genes encode scaffold receptors that can bind several different ligands, and also associate with many other receptors and modify their activity. Further, it has been confirmed that they play important roles in the shaping of major organs and tissues such as the nervous system and the vascular system, and that they can modulate immune responses.
The book offers a helpful guide for biomedical researchers and all scientists active in the neurosciences, vascular and molecular biology, as well as developmental biology and immunology.
Editors and Affiliations
About the editors
Bibliographic Information
Book Title: The Neuropilins: Role and Function in Health and Disease
Editors: Gera Neufeld, Ofra Kessler
DOI: https://doi.org/10.1007/978-3-319-48824-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-48822-6Published: 15 February 2017
Softcover ISBN: 978-3-319-84022-2Published: 15 July 2018
eBook ISBN: 978-3-319-48824-0Published: 06 February 2017
Edition Number: 1
Number of Pages: VI, 239
Number of Illustrations: 10 b/w illustrations, 28 illustrations in colour
Topics: Immunology, Molecular Medicine, Cancer Research, Neurosciences, Developmental Biology, Cell Biology