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The Neuropilins: Role and Function in Health and Disease

  • Book
  • © 2017

Overview

  • Provides basic as well as current scientific knowledge on neuropilins structure and function

  • Reader will learn about each major biological system, affected by neuropilins

  • Discusses potential medical implications

  • Presents a state-of-the art work for biomedical scientists

  • Includes supplementary material: sn.pub/extras

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Table of contents (13 chapters)

  1. Molecular Mechanisms of Neuropilin Mediated Signal Transduction

  2. Neuropilins as Regulators of Developmental and Immune Processes

  3. The Role of the Neuropilins in Cancer and in Immune Disorders

Keywords

About this book

This book covers basic research topics such as the structure-function relationships of neuropilins and mechanisms of neuropilin-mediated signal transduction, details the most important roles of the neuropilins in developmental biology, and addresses their roles in various conditions such as cancer and various eye diseases. 

The two neuropilin genes encode scaffold receptors that can bind several different ligands, and also associate with many other receptors and modify their activity. Further, it has been confirmed that they play important roles in the shaping of major organs and tissues such as the nervous system and the vascular system, and that they can modulate immune responses. 

The book offers a helpful guide for biomedical researchers and all scientists active in the neurosciences, vascular and molecular biology, as well as developmental biology and immunology.

 

Editors and Affiliations

  • Department Anatomy and Cell Biology, Israel Institute of Technology Technion, Haifa, Israel

    Gera Neufeld, Ofra Kessler

About the editors

Gera Neufeld is Professor of Cell Biology at the Faculty of Medicine, Technion, Israel Institute of Technology. Ofra Kessler, phD, is Senior Researcher in the laboratory of Anatomy and Cell Biology by Prof. Neufeld.

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