Overview
- Children with cancer
- Pediatric physicians
- Researchers in the field of pediatric cancer
- Scientists involved in the development of cancer drugs
Part of the book series: Pediatric Cancer (PECA, volume 1)
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Table of contents (24 chapters)
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Front Matter
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Introduction
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Front Matter
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Diagnosis and Biomarkers
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Front Matter
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Therapy
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Front Matter
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Keywords
About this book
Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.
Editors and Affiliations
Bibliographic Information
Book Title: Neuroblastoma
Editors: M.A. Hayat
Series Title: Pediatric Cancer
DOI: https://doi.org/10.1007/978-94-007-2418-1
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2012
Hardcover ISBN: 978-94-007-2417-4Published: 03 November 2011
Softcover ISBN: 978-94-017-7909-8Published: 23 August 2016
eBook ISBN: 978-94-007-2418-1Published: 02 November 2011
Series ISSN: 2211-7997
Series E-ISSN: 2211-8004
Edition Number: 1
Number of Pages: XVIII, 262
Topics: Cancer Research, Pediatrics, Diagnostic Radiology, Pediatric Surgery