Overview
- Contains a collection chapters from world’s top experts describing systems approaches to cancer research Focussed on the use of latest integrated and systems technologies unique to cancer drug discovery Covers two highly appealing subjects (a) future cancer drugs and (b) personalized medicine New and emerging Systems concepts and technologies
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Table of contents (18 chapters)
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Systems Biology in Cancer
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Systems Approaches to Understand Cancer Progression
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Systems and Network Biology in Decoding miRNA Complexity
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Network Modeling in Cancer Drug Discovery and Clinical Trials
Keywords
About this book
Systems Biology in Cancer Research and Drug Discovery provides a unique collection of chapters, by world-class researchers, describing the use of integrated systems biology and network modeling in the cancer field where traditional tools have failed to deliver expected promise. This book touches four applications/aspects of systems biology (i) in understanding aberrant signaling in cancer (ii) in identifying biomarkers and prognostic markers especially focused on angiogenesis pathways (iii) in unwinding microRNAs complexity and (iv) in anticancer drug discovery and in clinical trial design. This book reviews the state-of-the-art knowledge and touches upon cutting edge newer and improved applications especially in the area of network modeling. It is aimed at an audience ranging from students, academics, basic researcher and clinicians in cancer research. This book is expected to benefit the field of translational cancer medicine by bridging the gap between basic researchers, computational biologists and clinicians who have one ultimate goal and that is to defeat cancer.
Editors and Affiliations
Bibliographic Information
Book Title: Systems Biology in Cancer Research and Drug Discovery
Editors: Asfar S. Azmi
DOI: https://doi.org/10.1007/978-94-007-4819-4
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media Dordrecht 2012
Hardcover ISBN: 978-94-007-4818-7Published: 29 September 2012
Softcover ISBN: 978-94-007-9435-1Published: 15 October 2014
eBook ISBN: 978-94-007-4819-4Published: 29 September 2012
Edition Number: 1
Number of Pages: XII, 423
Topics: Biomedicine general, Cancer Research, Systems Biology, Bioinformatics