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Future Aspects in Contraception

Proceeding of an International Symposium held in Heidelberg, 5–8 September 1984 Part 1 Male Contraception

  • Conference proceedings
  • © 1985

Overview

Editors:
  1. B. Runnebaum

    1. Division of Gynaecological Endocrinology, Department of Obstetrics and Gynaecology, University of Heidelberg, Heidelberg 1, West Germany

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  2. T. Rabe

    1. Division of Gynaecological Endocrinology, Department of Obstetrics and Gynaecology, University of Heidelberg, Heidelberg 1, West Germany

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  3. Ludwig Kiesel

    1. Division of Gynaecological Endocrinology, Department of Obstetrics and Gynaecology, University of Heidelberg, Heidelberg 1, West Germany

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Table of contents (15 papers)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Future aspects in contraception: an overview

    • T. Rabe, L. Kiesel, B. Runnebaum
    Pages 1-127

  3. Steroidal contraception — experimental background

    • F. Neumann
    Pages 129-144

  4. Male contraception in the preclinical evaluation

    • K.-W. Von Eickstedt
    Pages 145-152

  5. Long-acting steroids for male contraception

    • H. Kuhl, H.-J. Born, M. Schneider, J. Sandow, W. Singer, H.-D. Taubert
    Pages 153-166

  6. Relationship between ligand structure and affinity for androgen binding protein

    • T. J. Lobl, G. R. Cunningham, J. A. Campbell, D. J. Tindall
    Pages 167-178

  7. Male contraception with LHRH agonists

    • A. Belanger, F. Labrie, Y. Tremblay, A. Dupont, R. St-Arnaud
    Pages 179-189

  8. The epididymis as a target for contraception: role of testosterone metabolism

    • M. Motta, S. Zoppi, L. Martini
    Pages 191-198

  9. Effect of 6 month treatment with a gonadotrophin releasing hormone agonist analogue on endocrine and histological features of human testis tissue

    • I. Huhtaniemi, H. Nikula, M. Parvinen, S. Rannikko
    Pages 199-204

  10. The future of plant-derived chemicals as contraceptive agents

    • N. R. Farnsworthv, A. S. Bingel
    Pages 205-218

  11. Gossypol—the male fertility-regulating agent

    • N. R. Kalla
    Pages 219-227

  12. Cottonseed oil for birth control

    • G.-Z. Liu
    Pages 229-236

  13. Antifertility activity of (—)-gossypol

    • S. A. Matlin, R. H. Zhou
    Pages 237-241

  14. Monoclonal antibodies directed against human sperm antigens

    • N. J. Alexander
    Pages 243-250

  15. Influence of psychotropic drugs, gossypol and acetylcholine receptor blockers on the motility of human spermatozoa in vitro

    • F. Krassnigg, R. Placzek, R. Engl, J. Frick, W.-B. Schill
    Pages 251-255

  16. Investigations on the spermicidal action of cellulose trisulphuric acid ester

    • W.-B. Schill, H. H. Wolff
    Pages 257-265

  17. Back Matter

    Pages 267-270
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Keywords

About this book

Atrophy of gonadotrophin producing cells Exogenously LH synthesis administered androgens and release or anabolic steroids are decreased Prostate Testes Normal function. Testosterone synthesis in The deficit of endogenously Leydig cells is decreased. The synthesized testosterone is exogenously administered compensated for by the steroid is not able to exogenously administered compensate for the deficit of steroid endogenously synthesized testosterone Figure 2 Intratesticular and serum testosterone concentrations after treatment with andro­ gens or anabolic steroids in order to substitute for the peripheral androgen deficiency and to achieve azoospermia. Because this steroid is alkylated in position 17, toxic effects on liver function can not be excluded. Danazol offers no advantages as compared with other anabolic steroids; rather, disadvantages. Numerous experiments of this type have been performed during the last 40 or 50 years. The outcome in each case was more or less identical: with a certain dose of an androgen or anabolic steroid it is possible to inhibit spermatogenesis without interfering with other androgen-dependent func­ tions, including libido (potentia coeundi) and accessory sexual glands. On the basis of this pharmacological-endocrinological background, androgens and anabolic steroids can be used for male fertility control, and several clinical trials have been performed during the last 10-15 years. Some of 1 these studies 2-23 are mentioned in Table 2.

Editors and Affiliations

  • Division of Gynaecological Endocrinology, Department of Obstetrics and Gynaecology, University of Heidelberg, Heidelberg 1, West Germany

    B. Runnebaum, T. Rabe, Ludwig Kiesel

Bibliographic Information

  • Book Title: Future Aspects in Contraception

  • Book Subtitle: Proceeding of an International Symposium held in Heidelberg, 5–8 September 1984 Part 1 Male Contraception

  • Editors: B. Runnebaum, T. Rabe, Ludwig Kiesel

  • DOI: https://doi.org/10.1007/978-94-009-4910-2

  • Publisher: Springer Dordrecht

  • eBook Packages: Springer Book Archive

  • Copyright Information: MTP Press Limited 1985

  • Softcover ISBN: 978-94-010-8675-2Published: 06 October 2011

  • eBook ISBN: 978-94-009-4910-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: 280

  • Topics: Gynecology

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