Overview
- Introduces different animal models of human birth defects
- Summarizes the current knowledge of a variety of common human birth defects
- Discusses the essential roles of animal models in the effort to understand underlying mechanisms of human birth disorders
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1236)
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Table of contents (9 chapters)
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Front Matter
Keywords
About this book
This book focuses on the use of animal models to study various human defects. It summarizes our current understanding of a variety of common human birth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms leading to many of these developmental disorders has hindered effective prevention and early intervention strategies. Studies using animal models have provided essential insights into several human birth defects. This book serves as a valuable reference resource for researchers and graduate students who are interested in learning the basic principles as well as the latest advances in the study of the mechanisms of human birth defects.
Editors and Affiliations
About the editor
Dr. Aimin Liu completed his PhD at the lab of Dr. Alex Joyner at New York University School of Medicine, working on the roles of Fgf8 in mouse mid/hindbrain development. He subsequently worked as a Postdoc Fellow with Drs Lee Niswander and Kathryn Anderson at the Sloan-Kettering Institute in New York and University of Colorado at Denver, where he was involved in the genetic analysis of limb and neural tube development. He started his own lab at the Biology Department of the Pennsylvania State University, where he currently works as an Associate Professor. His research focuses on the roles of the primary cilium and the Hedgehog signaling pathway in mouse development. He is a member of AAAS and the Society for Developmental Biology.
Bibliographic Information
Book Title: Animal Models of Human Birth Defects
Editors: Aimin Liu
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-981-15-2389-2
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2020
Hardcover ISBN: 978-981-15-2388-5Published: 18 April 2020
Softcover ISBN: 978-981-15-2391-5Published: 18 April 2021
eBook ISBN: 978-981-15-2389-2Published: 17 April 2020
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VII, 244
Number of Illustrations: 11 b/w illustrations, 43 illustrations in colour
Topics: Laboratory Medicine, Animal Models, Molecular Medicine